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Austin Reed of the Western Kentucky Hilltoppers throws a pass as we share our favorite Western Kentucky vs. Louisiana Tech prediction.
Austin Reed of the Western Kentucky Hilltoppers throws a pass in the second quarter against the Ohio State Buckeyes at Ohio Stadium in Columbus, Ohio. Photo by Dylan Buell/Getty Images via AFP.

We look into whether the Western Kentucky Hilltoppers can get more offensive production on the road as we make our Western Kentucky-Louisiana Tech prediction based on the best college football odds.

Western Kentucky (3-2) has had a season of contrasting performances, resembling a Jekyll and Hyde scenario, where its play significantly differs between home and away games. Nevertheless, as the Hilltoppers prepare for Thursday's showdown against Louisiana Tech (3-3), they find themselves as favorites by nearly a touchdown.

The big question remains whether Western Kentucky can break the pattern and achieve a convincing victory on Thursday night.

As part of our college football predictions for Week 6, here is our best Western Kentucky vs. Louisiana Tech prediction and our college football picks (odds via our best college football betting sites; pick confidence based on a 1-to-5-star scale).

Western Kentucky vs. Louisiana Tech prediction 

Western Kentucky -6 (-110 via DraftKings) ⭐⭐⭐

Western Kentucky has a notable edge in the metrics over the Louisiana Tech Bulldogs entering this Week 6 matchup as part of our college football predictions for Week 6, as the Hilltoppers rank 66th in overall efficiency according to FPI. The Bulldogs are down toward the bottom of the table in FBS at 110th in total efficiency. 

Although Louisiana Tech has logged three wins on the season, those victories have come against one FCS opponent and two teams that rank 120th or lower in overall efficiency. LA Tech also gets dinged for a home loss to North Texas, another team that sits outside the top 100 in the efficiency metrics.

Western Kentucky hasn’t had outright success in road games this season, losing to both Ohio State and Troy. However, Troy ranks above WKU in efficiency and only defeated the Hilltoppers by two points in that contest. Mitigating some minor road woes for WKU is the fact that Louisiana Tech is 1-2 ATS at home.

While LA Tech ranks favorably in pass defense, I don’t consider it a concern for WKU’s pass-heavy offense; the ranking is a major misnomer. Nobody has really needed to throw against Louisiana Tech because of how dreadful its run defense has been (130th in FBS). 

Louisiana Tech is a bad team getting set to face a capable offense. WKU has managed to win similar mismatches by double-digits to this point, so I expect a similar outcome here.

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Western Kentucky vs. Louisiana Tech best odds

DraftKings (-110)

DraftKingsFanDuelBetMGMCaesarsbet365
WKU -6WKU -6.5WKU -6.5WKU -6.5WKU -6.5
-110-105-110-110-110

Western Kentucky sits at -6.5 at the majority of our recommended sportsbooks, but DraftKings currently offers the highest-quality odds for bettors looking to back the Hilltoppers. DraftKings lists WKU at -6 with standard -110 odds.

FanDuel’s odds of -105 are the best on the board, but they are attached to that lesser -6.5 line. Avoid BetMGM, Caesars, and bet365 at current offerings, as there’s no advantage to their line or odds at -6.5 and -110. 

If the line should dip below -6, we would boost this recommendation to four stars.

Western Kentucky vs. Louisiana Tech odds

Western Kentucky vs. Louisiana Tech odds analysis

Western Kentucky opened as a 7-point road favorite and has seen that number stay pretty stable between -6 and -6.5. Only 45% of spread wagers have been placed on the Hilltoppers, so Louisiana Tech is catching the majority of bets at this point.

The total opened at 60.5 and has dropped slightly down to 59.5. At this time, 77% of wagers on the total have gone Over.

Western Kentucky vs. Louisiana Tech game info

  • When: Thursday, Oct. 5, 2023 at 8 p.m. ET
  • Where: Joe Aillet Stadium, Ruston, LA
  • How to watch: ESPNU
  • Weather: 76 degrees, 5 mph winds, 33% precipitation

Western Kentucky-Louisiana Tech prediction made 10/03/2023 at 4 p.m. ET.

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