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College Football Predictions Week 6 2023: Picks & Odds for Marquee Games

Esten McLaren

Last Updated: October 7, 2023 6:34 AM EDT • 1 min 44 sec read.

Caleb Williams #13 of the USC Trojans warms up before taking the field as we look at all of our college football predictions for Week 6
Caleb Williams #13 of the USC Trojans warms up before taking the field on offense in the third quarter against the Colorado Buffaloes at Folsom Field on September 30, 2023 in Boulder, Colorado. Dustin Bradford/Getty Images/AFP

We're rounding up all of our college football predictions for Week 6 as we try to get the better of the college football odds with games being played every day from Wednesday through Saturday.

Marquee games on the college football Week 6 schedule include No. 3 Texas hosting No. 12 Oklahoma, No. 1 Georgia welcoming No. 20 Kentucky to town, and No. 10 Notre Dame visiting No. 25 Louisville. But our college football predictions have you covered from Wednesday through Saturday as the week gets started with a pair of Wednesday contests.

Read on as we break down the odds from our best college football betting sites for our Week 6 predictions on all of the marquee games.

College football picks and predictions for Week 6

College football predictions for Saturday

Oklahoma vs. Texas pick: Under 60.5 (-110 via DraftKings) ⭐⭐⭐

Oklahoma-Texas pick made by Phil Wood

Maryland vs. Ohio State pick: Over 56.5 (-106 via FanDuel) ⭐⭐⭐⭐

Maryland-Ohio State pick made by Mike Spector

LSU vs. Missouri pick: Over 63 (-113 via BetRivers) ⭐⭐⭐

LSU-Missouri pick made by Mike Spector

Alabama ML vs. Texas A&M pick: (-120 via Caesars) ⭐⭐⭐⭐

Alabama-Texas A&M pick made by Brenden Schaeffer

Colorado -2.5 first-half spread vs. Arizona State pick: (-110 via Caesars) ⭐⭐⭐⭐

Colorado-Arizona pick made by Shane Jackson

Kentucky vs. Georgia  -14.5 (-105 via FanDuel) ⭐⭐⭐

Kentucky-Georgia pick made by Mike Spector

Michigan team total Under 13.5 points vs. Minnesota pick: (-105 via bet365) ⭐⭐⭐

Michigan-Minnesota pick made by Phil Wood

Notre Dame -6 vs. Louisville pick: (-110 via DraftKings) ⭐⭐⭐⭐

Notre Dame-Louisville pick made by Brenden Schaeffer

Arizona vs. USC pick: Over 71.5 (-110 via FanDuel, BetMGM) ⭐⭐⭐⭐

Arizona-USC pick made by Brenden Schaeffer

College football expert picks for Week 6

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College football odds pages

CFP National Championship OddsSEC OddsBig 12 Odds
Heisman Trophy OddsBig Ten OddsPac-12 Odds
College Football Playoff OddsMountain West OddsACC Odds

Here are our best college football betting sites:

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* Bonuses not applicable in Ontario.

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Written By:
Esten McLaren
Esten is the Senior Publishing Editor for SportsbookReview.com. He has been in the sports betting industry since the legalization of mobile sports betting in New Jersey, and with SportsbookReview prior to the launch of sports betting in Ontario. Esten's previous stops include the USA TODAY network, including GolfWeek. He previously worked in the fantasy sports industry, with FNTSY Sports Network, theScore, and USA TODAY. Esten graduated from the College of Sports Media with a diploma in Radio and Television Sports Broadcasting after acquiring a degree in Biological Sciences from the University of Guelph. He has appeared on FNTSY Sports Network, VSiN, and VSiN's Long Shots podcast, where he correctly called Will Zalatoris as the winner of the 2022 FedEx St. Jude Championship. Esten is a big proponent of the entertainment side of sports betting and loves to dip his toes into the novelty and alt-markets while chasing long shots with reduced wagers on golf outrights and futures markets. He's also been known to sprinkle some lunch money on touchdown-scorer parlays with two notable hits still funding his bankroll. Esten looks at sports betting much like golf and advises beginner bettors to compete against themselves rather than being concerned with what others may or may not be doing based on social media claims.