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Colorado Buffaloes Heisman Trophy odds favorite Travis Hunter flashes a No. 1 after a win, and we look at his team with our Oklahoma State vs. Colorado prediction.
Colorado Buffaloes Heisman Trophy odds favorite Travis Hunter flashes a No. 1 after a win. Photo by Cris Tiller/USA TODAY NETWORK via Imagn Images.

The Colorado Buffaloes no longer control their College Football Playoff odds destiny after last week’s loss but still look to make one last statement in the regular-season finale against the Oklahoma State Cowboys. 

  • Colorado is one of four teams tied atop the Big 12 standings at 6-2
  • There are over 200 Big 12 Championship Game scenarios 
  • Oklahoma State (0-8) is the only winless team in Big 12 play this season

Our Oklahoma State vs. Colorado prediction takes a flier on the last-place Cowboys to cover the big spread against what could be a deflated Buffaloes squad.

Colorado is a 16.5-point favorite with the O/U bouncing around at 65 or 65.5. Kickoff from Folsom Field is expected for noon E.T. airing on ABC/ESPN+.

Be sure to also check out our Oklahoma State vs. Colorado early picks to see how this game has evolved during the week, all part of our college football Week 14 predictions.

Oklahoma State vs. Colorado prediction & best bet

College football picks based on the odds from our best college football betting sites. Odds subject to change.

  • Against the spread pick: Oklahoma State +16.5 (-105 via BetMGM) vs. Colorado ⭐⭐
  • My best bet: Ollie Gordon II Over 77.5 rushing yards (-118 via Caesars) ⭐⭐⭐⭐

Oklahoma State vs. Colorado ATS prediction: Week 14

Oklahoma State to cover the spread: +16.5 ⭐⭐

Best odds: -105 via BetMGM | Implied probability: 51.22%

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Unmotivated Buffaloes?

Had Colorado beaten Kansas last week, it would have controlled its own destiny this week for a berth in the Big 12 Championship Game and a possible bye in the first round of the College Football Playoff. 

As it stands, Colorado would be left out of the Big 12 Championship if all four 6-2 teams win this week, as Arizona State and Iowa State would play for the conference title.

One school of thought is that Shedeur Sanders and Travis Hunter will go out with a bang, as this could be their final college football game ever (assuming each would opt out of their bowl game). 

But aside from trying to strengthen Hunter’s Heisman Trophy odds resume, it is hard to get motivated when there is seemingly so much less to play for this week compared to one week ago.

Oklahoma State is a contrarian play

Last week, Colorado attracted the fifth-most tickets and the second-highest amount of money among point spread wagers at DraftKings, and it is likely to be one of the most popular plays again facing an Oklahoma State team that is 1-7 ATS in its last eight games.

While it has not been covering with regularity, Oklahoma State has faced three opponents who were ranked at the time of the game, and it lost to two of them (Utah and BYU) by a field goal each.

Colorado’s run defense was exposed

Colorado’s run-defense grade was in the top 40 prior to holding Utah to 31 yards on 30 rushing attempts two games ago. 

However, the Buffaloes looked more like the team that finished last year with the No. 122 run-defense grade by allowing Kansas’ Devin Neal to run for 207 yards and three touchdowns, and he averaged 5.6 yards per carry.

The Buffaloes as a whole allowed 333 yards on the ground and 6.1 yards per rushing attempt in last week’s loss.

I am headed to BetMGM for my Oklahoma State spread play, as it is one of the only best sports betting sites offering less than the standard -110 juice to back the underdogs. Through its -105 odds, a $10 winning wager would pay out $19.52. 

Oklahoma State vs. Colorado best bet

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Ollie Gordon II Over 77.5 rushing yards ⭐⭐⭐⭐

Best odds: -118 via Caesars | Implied probability: 54.13%

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Devin Neal’s 207 rushing yards against Colorado last week were the second-most in his career, and was only the second 200-yard rushing day by any Big 12 player this season. 

Things do not get easier for the Buffaloes when facing the reigning Doak Walker Award winner, Ollie Gordon II. 

Gordon’s 870 rushing yards are nowhere near the 1,732 rushing yards he finished last season with. However, he is still the team’s workhorse back, with nearly 57% of the team’s carries and 147 more carries than the next closest teammate this season.

Gordon has averaged 5.4 yards per carry against AP Top 25 opponents this season, and his 25 carries two games ago were his second-most of the season. 

Gordon has 15 or fewer rushing attempts in five of the previous eight games, but head coach Mike Gundy will likely look to replicate Kansas’ success of running the football.

Gordon has eclipsed this total in three of the last five games and was close to a fourth with a 77-yard day mixed in. Thus, Caesars is offering more than a fair number, and its -118 odds would net $8.47 in profits on a $10 winning wager. 

Oklahoma State vs. Colorado odds

See all of this week's college football odds and NCAAF scores.

Oklahoma State vs. Colorado live odds

Oklahoma State vs. Colorado opening odds:

  • Oklahoma State: +16.5 (-110 via BetMGM)
  • Colorado: -16.5 (-110 via BetMGM)

Oklahoma State vs. Colorado game info

  • When: Friday, Nov. 29
  • Kickoff: Noon ET 
  • Where: Folsom Field (Boulder, Colo.)
  • How to watch: ABC/ESPN+
  • Weather: 45 degrees, 1% chance of precipitation, wind 6 mph N
  • Favorite: Colorado -16.5 (-115 via BetMGM)

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