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Texas quarterback Quinn Ewers looks to pass against Kentucky. The Longhorns game against Texas A&M is the biggest game of our Week 14 college football predictions.
Texas quarterback Quinn Ewers looks to pass against Kentucky. Photo by Scott Wachter via Imagn Images.

In the final week of the regular season, our Week 14 college football predictions highlight the can't-miss matchups, including several of the biggest rivalries in the sport.

  • One win away from securing a spot in the Big Ten Championship, college football championship odds favorite Ohio State takes on hated rival Michigan
  • Colorado is desperate for a win to get a chance at the Big 12 Championship, with Heisman Trophy odds favorite Travis Hunter leading the Buffaloes against Oklahoma State
  • In arguably the most important game for the College Football Playoff odds, the Lone Star Showdown is finally back with the winner of Texas vs. Texas A&M going to the SEC Championship

Thanks to rivalry week coinciding with Thanksgiving, there's a plethora of AP Top 25 teams playing important games ahead of conference championship weekend next week.

College football picks & predictions Week 14

Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Don't miss the rest of our Week 14 college football picks.

College football odds for Saturday

Oklahoma vs. LSU odds

Prediction: Jackson Arnold Over 64.5 rushing yards (-114 via FanDuel) 

Pick made by Gabe Henderson

  • When: Saturday, Nov. 30 (7 p.m. ET)
  • Where: Tiger Stadium (Baton Rouge, La.)
  • How to watch: ESPN
  • Moneyline: Oklahoma (+185) | LSU (-225)
  • Spread: Oklahoma +6.5 (-112) | LSU -6.5 (-108)
  • Total: 47 (-112/-108)

Texas vs. Texas A&M odds

Prediction: Texas A&M +5.5 (-110 via bet365)⭐⭐⭐⭐

Pick made by Matt MacKay.

  • When: Saturday, Nov. 30 (7:30 p.m. ET)
  • Where: Kyle Field (College Station, Texas)
  • How to watch: ABC
  • Moneyline: Texas (-230) | Texas A&M (+190)
  • Spread: Texas -6 (-108) | Texas A&M +6 (-112)
  • Total: 48.5 (-110/-110)

College football picks roundup: Week 14

College football betting odds pages

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