College Football Week 6 Predictions: Picks & Odds for Marquee Games

C Jackson Cowart

Last Updated: October 4, 2024 6:38 AM EDT • 1 min 44 sec read. Twitter link Google News Link

Miami Hurricanes quarterback Cam Ward (1) celebrates as we offer our college football Week 6 predictions. — Miami Hurricanes quarterback Cam Ward celebrates against the Virginia Tech Hokies. Photo by Sam Navarro / Imagn Images.

After the biggest week of the college football season so far, our college football Week 6 predictions feature just one ranked matchup but a whole host of tricky conference matchups for top teams.

The top game on Saturday kicks off at noon ET when Missouri faces Texas A&M in a matchup between college football championship odds contenders from the SEC.

Later in the day, Michigan faces Washington rematch of last year's title game as the Wolverines look to keep their College Football Playoff odds alive for another week. That contest kicks off at 7:30 p.m. ET on NBC.

Saturday's action wraps with Heisman Trophy odds contender Cam Ward and eighth-ranked Miami traveling to face California at 10:30 p.m. ET in their first clash as ACC foes.

College football picks & predictions Week 6

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Miami vs. California player props

Don't miss the rest of our Week 6 college football picks.

College football odds for Saturday

College football odds via DraftKings and subject to change. Follow the latest college football scores for line history and matchup info.

Michigan vs. Washington odds

Prediction: Washington -1.5 (-108 via FanDuel) ⭐⭐⭐⭐

Pick made by Brenden Schaeffer

When: Saturday, Oct. 5 (7:30 p.m. ET)
Where: Alaska Airlines Field at Husky Stadium (Seattle)
How to watch: NBC
Moneyline: Michigan +115 | Washington -140
Spread: Michigan +2.5 (-105) | Washington -2.5 (-115)
Total: 40.5 (-110/-110)

Miami vs. California odds

Prediction: California +10.5 (-105 via Caesars) vs. Miami ⭐⭐⭐⭐

Pick made by Mike Spector

When: Saturday, Oct. 5 (10:30 p.m. ET)
Where: California Memorial Stadium (Berkeley, Calif.)
How to watch: ESPN
Moneyline: Miami -375 | California +295
Spread: Miami -10 (-112) | California +10 (-108)
Total: 54.5 (-112/-108)

College football picks roundup: Week 6

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Written By:
C Jackson Cowart

C Jackson Cowart is a publishing editor and lead writer for Sportsbook Review. An award-winning writer, reporter, and editor with a decade of sports media experience, "C-Jax" has worked with ESPN, Forbes, theScore, and various daily newspapers before joining the Sportsbook Review team. He's a proud graduate of the University of North Carolina, where he served as a beat writer for the Tar Heels' championship run through the NCAA men's basketball tournament in 2017. Jackson has spent the last five years covering sports betting as a predictive analyst, features writer, and industry reporter. Since joining the team in 2023, he's played a key role in Sportsbook Review's coverage of the Super Bowl, March Madness, and NBA playoffs while serving as the lead writer for the growing WNBA and NASCAR betting scenes. Though he's cashed some big bets over the years -- including Lamar Jackson to win MVP (twice) -- he's still haunted by enough second-place bet slips to wallpaper his home office. While Jackson is a committed "process over results" bettor with a keen eye for advanced stats and subtle bias in futures markets, he also embraces sports betting as a vehicle for entertainment and personal investment. He's written about everything from hot dogs to groundhogs and still hasn't forgiven his "inside source" for a sabotaged bet on the Gatorade color in Super Bowl LV.