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Mississippi Rebels quarterback Jaxson Dart reacts after a touchdown against the Kentucky Wildcats.
Mississippi Rebels quarterback Jaxson Dart reacts after a touchdown against the Kentucky Wildcats. Photo by Petre Thomas via Imagn Images.

The SEC is home to four of the top five teams in the AP poll, and three of them are in action during a loaded Week 6 college football slate.

  • Auburn is 0-2 in SEC play in consecutive seasons for the first time in school history
  • LSU’s Garrett Nussmeier ended September as the FBS leader in passing yards (1,652)
  • Alabama improved to 64-2 in September since 2008 and ended Georgia’s 42-game regular-season winning streak last week

Our SEC predictions and best bets for Week 6 expect two of the conference’s best quarterbacks to be held in check, while one of the conference’s highest-ranked teams is due for its first loss. It all comes as part of our college football Week 6 predictions.

SEC best bets: Week 6

College football odds as of Friday and subject to change. Track the college football scores for the latest line movement and matchup info.

  • Jaxson Dart Under 288.5 passing yards (-118 via Caesars) vs. South Carolina  ⭐⭐⭐
  • Nico Iamaleava Under 30.5 rushing yards (-115 via bet365) vs. Arkansas  ⭐⭐⭐⭐
  • Texas A&M -2 (-110 via Caesars) vs. Missouri  ⭐⭐⭐⭐

Best SEC predictions this week

College football picks made Friday; odds subject to change. Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Jaxson Dart Under 288.5 passing yards (-118) ⭐⭐⭐

Kentucky’s defense had its way with the Ole Miss offense last week, holding the Rebels to 17 points (38 below their previous season average). Because of Ole Miss’ offensive inefficiency, it suffered its first loss in five seasons when allowing 20 or fewer points.

Jaxson Dart had one completion of 20-plus air yards last week after entering the game with an FBS-high 15 such completions. Dart could not get into a rhythm as the Rebels' offensive line allowed pressure on a season-high 36% of dropbacks last week, and he should be in for a similarly frustrating game going against a Gamecocks front that averages 3.5 sacks per game.

South Carolina’s Kyle Kennard’s 5.5 sacks are the most in the SEC, and the end on the other side, Dylan Stewart, has chipped in 2.5 sacks and two forced fumbles.

Under backers are getting a great number at Caesars, as Dart’s O/U for passing yards is as low as 280.5. With Caesars’ -118 odds, a $10 winning wager would pay out $18.47.

Best odds: -118 via Caesars | Implied probability: 54.13%

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Nico Iamaleava Under 30.5 rushing yards (-115) ⭐⭐⭐⭐

This O/U is right in line with Nico Iamaleava’s season total, as he has averaged 29 rushing yards per game. However, Tennessee faces an Arkansas defense that is more susceptible to the pass, ranking 89th in passing yards per game allowed.

Tennessee head coach Josh Heupel would likely be all for padding Iamaleava’s statistics for his Heisman Trophy odds resume, and the Volunteers are the nation’s highest-scoring team.

But Tennessee’s next two games are against arguably its biggest SEC rival (Florida) and a home game with No. 1 Alabama, and Heupel will likely run Iamaleava less to make sure he is fully healthy for that gauntlet.

There are still recent memories of losing starting quarterback and Heisman hopeful Hendon Hooker to a torn ACL two years ago, so it would not be surprising to see Iamaleava placed in bubble wrap metaphorically ahead of the team’s toughest stretch of games.

This line is as low as 28.5 at FanDuel, so Under backers are getting the best number and price at bet365.

Best odds: -115 via bet365 | Implied probability: 53.49%

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Texas A&M -2 (-110) ⭐⭐⭐⭐

This is Missouri’s first time playing its initial road game in the month of October since 2017 (excluding the COVID-impacted 2020 season), and it faces one of the most intimidating crowds in the conference at Kyle Field.

Missouri’s offense has produced 15 20-plus yard plays, averaged six yards per play, and scored 15 touchdowns. By contrast, an Auburn offense which many would have considered to have underperformed to this point in the season has 34 20-plus yard plays, averaged 7.6 yards per play, and scored 22 total touchdowns.

The Aggies allowed 5.3 yards per play in a Week 5 win against Arkansas, which was their season-low against an FBS opponent this season. And Texas A&M’s offense has some momentum, with Marcel Reed seeking to be the first Aggies quarterback with multiple passing touchdowns in four straight games since 2020.

I expect Texas A&M to improve to 3-0 in SEC play for the second time in the last 20 seasons and am taking advantage of the two-point spread at Caesars, as most of the other best sports betting sites sites are a half-point higher at -2.5.

Best odds: -110 via Caesars | Implied probability: 52.38%

SEC picks roundup: Week 6

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