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Liverpool's Brazilian striker Roberto Firmino celebrates scoring his team's first goal during the UEFA Champions League Group A football match between Glasgow Rangers and Liverpool at the Ibrox Stadium, in Glasgow, on October 12, 2022.
Liverpool's Brazilian striker Roberto Firmino celebrates scoring his team's first goal during the UEFA Champions League Group A football match between Glasgow Rangers and Liverpool at the Ibrox Stadium, in Glasgow, on October 12, 2022. Photo by Andy Buchanan via AFP.

One European giant looks to get back on track sitting in the middle of the table, while the other looks to continue their dominance for a back-to-back-to-back Premier League title.

The Reds are enduring a rough start to the season at 2-4-2, while Manchester City are continuing to roll with Erling Haaland up front.

Here are our Liverpool-Manchester City Premier League picks for Matchday 11 (odds via DraftKings Sportsbook and FanDuel Sportsbook; pick confidence based on a 1-to-5-star scale).

Liverpool vs. Manchester City Game Info

Date: Sunday, Oct. 16, 11:30 a.m. ET
TV: fuboTV, NBC Sports
Location: Anfield, Liverpool, England
Weather: 67 degrees, 20% chance of precipitation, 16-mph winds

Liverpool vs. Manchester City Picks

  • Spread: Manchester City -0.75 (+105 via DraftKings) ★★★
  • Over/Under: Over 3.5 (+116 via FanDuel) ★★★★
  • Prop pick: Roberto Firmino anytime goal scorer (+230 via FanDuel) ★★★

Liverpool vs. Manchester City ATS Pick

Manchester City -0.75 (+105) ★★★

Manchester City haven’t beaten Liverpool since February of 2021, but their last four contests have either been a draw or decided by a single goal.

This season looks different for the reigning champions. Manchester City is the only undefeated team in the EPL and has scored 33 goals through nine games. They won each of their last three Premier League games by at least three goals.

Liverpool is doing well in Champions League play, but in the Premier League have won just one of their last four games. They conceded six goals in their last two games. City’s high-power attack will be a force against a Liverpool team that has conceded 12 times this season.

Liverpool vs. Manchester City O/U Pick

Over 3.5 (+116) ★★★★

City alone are averaging 3.67 goals per game. They scored two or fewer goals in a game just twice this season, and they managed to get on the scoresheet every single game.

Haaland sits at an expected goal rate of 9.0 for the season and an expected goal rate of 1.80 per 90 minutes. Pair that with Liverpool regaining their scoring confidence after Mohamed Salah recorded the fastest hat-trick in Champions League history on Wednesday, and this game is set to be a sixth-straight multi-goal affair.

Liverpool vs. Manchester City Prop Pick

Firmino anytime scorer (+230) ★★★

With Salah still sitting at just two goals in Premier League action, Roberto Firmino has stepped up as a goal producer for Liverpool. He scored against Arsenal last weekend before netting two against Rangers in midweek Champions League play.

Firmino has six goals and three assists in Premier League action, along with an expected goal rate of 2.9 with 1.16 goals per 90 minutes. He's adding 0.58 assists per 90 minutes. On top of his Premier League play, he is also a key attacker in all competitions.

While Salah’s hattrick stole headlines in a 7-1 Champions League win over Rangers, Firmino not only scored twice but netted Liverpool’s first two goals of the game.

Where to Bet on Liverpool vs. Manchester City Picks

FanDuel Sportsbook
Caesars Sportsbook
DraftKings Sportsbook
PointsBet
BetMGM

Liverpool-Manchester City picks made 10/14/2022 at 2:28 p.m. ET