Oilers vs. Panthers Predictions: Stanley Cup Game 6 Odds & Best Bet

The Florida Panthers are one win away from securing their second consecutive Stanley Cup. We examine whether they can make it happen at home in Game 6.
Oilers vs. Panthers Predictions: Stanley Cup Game 6 Odds & Best Bet
Pictured: Florida Panthers center Brad Marchand (63) shoots the puck against the Edmonton Oilers. Photo by Sergei Belski via Imagn Images.

The Edmonton Oilers have run out of lives to spare as they travel to Florida with one final chance to extend the Stanley Cup Final against the Florida Panthers. 

The Panthers can wrap up their second straight Stanley Cup on home ice as we offer our Oilers vs. Panthers predictions for Tuesday's Game 6, which expect another bounce-back outing from the visitors. Puck drop at Amerant Bank Arena is set for 8 p.m. ET (TNT), and the Panthers are the betting favorites across our best sports betting sites.

🔮 Oilers vs. Panthers prediction & picks for Game 6

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✅ Who will win Oilers vs. Panthers: Oilers (+120 via bet365) ⭐⭐⭐
✅ Best prop bet: Under 6.5 goals (-120 via bet365) ⭐⭐⭐

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💰 Panthers vs. Oilers best bet

Here is my best bet for Game 6 of the 2025 Stanley Cup Final:

🚨 Oilers ML 

  • Best odds: +120 via bet365 (bet $10 to win $12 profit)
  • Implied win probability: 45.45%

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The Oilers are officially out of Mulligans, down to the last out. For the fourth time in five games, Kris Knoblauch's team allowed the opening goal. This time, however, the Panthers weren't in a giving mood, shutting up shop and taking Game 5 comfortably.

Teams that win Game 5 of the Stanley Cup Final hoist the Holy Grail 73% of the time, making the Oilers' behemoth task increasingly unlikely. However, the Oilers have overcome adversity several times in these playoffs, so if there's any team that can drag the Panthers to a decisive Game 7, it's them.

I backed the Oilers since the start of the season, and I'm not about to waver. The Panthers are 5-4 at home, which should lift an Oilers crew that overcame a 3-0 first-period deficit when they last played at Amerant Bank Arena.

Another insipid start, however, will likely lead to the Panthers becoming back-to-back Stanley Cup winners, placing even more importance on bagging the opener.

Most of our best NHL betting sites have the Oilers pegged as +120 underdogs.

🏒 Panthers vs. Oilers odds tonight

Here are the live odds for Oilers vs. Panthers in Game 6. See the latest NHL odds for the Stanley Cup from our best NHL betting sites.

Odds analysis

After picking up a comfortable road win in Edmonton, bettors are backing the Panthers on home ice to get the job done on Tuesday. Early betting shows 60% of the wagers on the home side, with the Panthers opening at -140 on the moneyline and trading closer to -150 as of Monday morning. 

Despite a majority (68%) of tickets coming in on the Over, the odds are shading to the Under a little. The Under 6.5 opened at -115 but is now trading closer to -120. Despite bettors seemingly backing plenty of goals, sportsbooks seem to be preparing for a tighter defensive game.

💵 Best Stanley Cup betting sites

Want to bet on Panthers vs. Oilers in Game 6? Here are the best NHL betting sites and best sportsbook promos for the 2025 Stanley Cup Final:

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Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.