NFL Week 11 Odds: Lines, Spreads & Totals for Every Game

We look at the NFL odds and Week 11 lines & spreads, focusing on the biggest line movements and impact injuries moving the betting lines.
Jacksonville Jaguars mascot Jaxson de Ville gestures as we look at the Week 11 NFL odds.
Pictured: Jacksonville Jaguars mascot Jaxson de Ville gestures as we look at the Week 11 NFL odds. Photo by Kirby Lee-Imagn Images

📊 NFL odds Week 11, 2025

The NFL odds for Week 11 are via bet365.

Game Spread  Moneyline Over/Under
Jets vs. Patriots (TNF) Patriots -10.5 NYJ +400 / NE -550 46.5
Commanders vs. Dolphins (Madrid) Dolphins +1.5 WSH -125 / MIA +105 46.5
Panthers vs. Falcons Falcons -3.5 CAR +150 / ATL -180 44.5
Bears vs. Vikings Vikings -2.5 CHI +125 / MIN -150 47.5
Bengals vs. Steelers Steelers -6.5 CIN +230 / PIT -280 50
Packers vs. Giants Giants +7 GB -310 / NYG +250 46
Texans vs. Titans Titans +7.5 HOU -425 / TEN +325 38.5
Chargers vs. Jaguars Jaguars +1.5 LAC -125 / JAX +105 44.5
Buccaneers vs. Bills Bills -6 TB +210 / BUF -260 50.5
Seahawks vs. Rams Rams -2.5 SEA +125 / LAR -150 47.5
49ers vs. Cardinals Cardinals +1.5 SFO -125 / ARI +105 47.5
Ravens vs. Browns Browns +7.5 BAL -380 / CLE +300 41.5
Chiefs vs. Broncos  Broncos +2.5 KC -155 / DEN +130 45.5
Lions vs. Eagles (SNF) Eagles -1.5 DET +105 / PHI -125 48.5
Cowboys vs. Raiders (MNF) Raiders +3.5 DAL -185 / LV +155 51

Our NFL picks will be locked and loaded for Week 11, with only the Indianapolis Colts and New Orleans Saints on a bye.

  • The Thursday Night Football odds have the Patriots as a 10.5-point favorite against the AFC East rival Jets (8:15 p.m. ET, Prime Video)
  • The Dolphins are a 1.5-point "home" underdog when they clash with the Commanders in Madrid at 9:30 a.m. ET (NFL Network) on Sunday morning
  • Sunday's action wraps with an NFC powerhouse clash as the Eagles are the 1.5-point betting favorite according to the Sunday Night Football odds (8:20 p.m. ET, NBC)
  • There's just one game featured in the Monday Night Football odds, with the Cowboys lined as a 3.5-point road favorite against the host Raiders (8:15 p.m. ET, ABC/ESPN)

🏈 Jets vs. Patriots odds: Thursday Night Football

  • Kickoff: 8:15 p.m. ET from Gillette Stadium (Foxborough, Mass.)
  • How to watch: Prime Video

🏈 Commanders vs. Dolphins odds: NFL Spain game

  • Kickoff: 9:30 a.m. ET from Santiago Bernabeu (Madrid)
  • How to watch: NFL Network

🏈 Lions vs. Eagles odds: Sunday Night Football

  • Kickoff: 8:20 p.m. ET from Lincoln Financial Field (Philadelphia)
  • How to watch: NBC

🏈 Cowboys vs. Raiders odds: Monday Night Football

  • Kickoff: 8:15 p.m. ET from Allegiant Stadium (Las Vegas)
  • How to watch: ESPN/ABC

🔢 NFL Week 11 odds and lines

There's an advantage to betting early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your picks, the harder it becomes to identify edges and secure the best price on most sides or totals.

❓ Who's playing on prime time in Week 11?

Week 11 opens with the Jets and Patriots clashing on Thursday Night Football. The league heads to Madrid on Sunday morning for a Spain game between the Commanders and Dolphins. The Lions and Eagles are battling on Sunday Night Football, and the week wraps with the Cowboys and Raiders on Monday Night Football.


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