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Alec Pierce of the Indianapolis Colts celebrates after making a reception in the fourth quarter of a game against the Washington Commanders at Lucas Oil Stadium on October 30, 2022 in Indianapolis, Indiana.
Alec Pierce of the Indianapolis Colts celebrates after making a reception in the fourth quarter of a game against the Washington Commanders at Lucas Oil Stadium on October 30, 2022 in Indianapolis, Indiana. Photo by Dylan Buell/Getty Images via AFP.

The Indianapolis Colts can keep clinging to faint playoff hopes if they can handle a beatable Pittsburgh Steelers team at home on Monday night. Here are our Week 12 Steelers-Colts same-game parlay picks.

Since Jeff Saturday took the reins as interim head coach, the Colts have a win and a one-point loss to the otherwise dominant Philadelphia Eagles. Indianapolis looks to dispose of a downtrodden Pittsburgh group to maintain its forward momentum. 

Here are my same-game parlay picks for the Week 12 Monday Night Football matchup between the Steelers and Colts (odds via FanDuel Sportsbook; pick confidence based on a 1-to-5-star scale).

Check out our Steelers-Colts picks and our top Monday Night Football prop bets.

Steelers vs. Colts Odds

Steelers vs. Colts Same Game Parlay Picks

Same Game Parlay Predictions for Steelers vs. Colts

Colts -2.5 (-115) ★★★

The Colts are 3-2 ATS in home games this season, while Pittsburgh seems to falter away from its own stadium. With rookie quarterback Kenny Pickett factoring into this record, the Steelers are 1-4 outright and 2-3 ATS on the road.

The matchup is favorable for an Indianapolis group that has played inspired football the last couple of weeks under Saturday. Quarterback Matt Ryan has had some success slinging the ball for big yardage this season against defenses that are amenable to allowing it. Pittsburgh is one of those such defenses, as the Steelers permit an average of 272.1 passing yards per game to their opponents. That ranks 31st in the NFL.

Indianapolis ranks fourth in the league in total defense, allowing just 307.6 yards per game. Pittsburgh’s 312.2 yards of total offense per game ranks near the bottom of the league. A Steelers offense averaging just 17.0 points per game will struggle to score on Monday night. DraftKings lists Indy at -2.5 (-125) for the same-game parlay odds. FanDuel lists Indy at -2.5 (-115).

Campbell Over 46.5 receiving yards (-110) ★★★★

Though the Steelers allow plenty of yardage through the air, the return of T.J. Watt to the Pittsburgh defensive front should mean more pressure on Ryan to get the ball out quickly. That’s especially the case for a Colts offensive line that has ranked near the bottom of the league in most key statistics.

This combination of factors could mean a productive day for Colts receiver Parris Campbell, the emerging 25-year-old receiver who does his damage on short and intermediate routes. Campbell has been a preferred target of Ryan the last couple of weeks since the latter was re-installed as the Indianapolis starter. Campbell has yardage totals of 67 and 76 in those contests.

DraftKings has various alternate lines on Campbell’s yardage total, including 39.5 yards (-150o) and 49.5 yards (+110o). We prefer the standard FanDuel line at 46.5 yards (-110).

Pierce Over 36.5 receiving yards (-110) ★★★

The type of offensive flow that supports Alec Pierce’s explosive ability doesn’t necessarily match perfectly with the environment the Colts could see Monday. If Watt and Co. are harassing Ryan on a regular basis, Campbell could be the favored target over Pierce for the reasons detailed above.

But against Pittsburgh’s friendly secondary, it’s difficult to ignore how attainable the FanDuel total for Pierce’s receiving yards looks on Monday. Though he’s fallen short of the line in three straight games, Pierce had smashed it for six consecutive weeks earlier in the year. Whether it was with Ryan or Sam Ehlinger under center, Pierce was developing into a consistent force before the Colts made the coaching change.

I don’t view Saturday as Pierce’s kryptonite, though. The rookie drew eight targets last week but fell into some bad variance by catching only three of those balls for 28 yards. If Ryan keeps looking in Pierce's direction with that level of frequency, he’ll clear the FanDuel line on Monday. We prefer the -110 odds via FanDuel over the alternate lines (29.5 yards, -175) offered by DraftKings.

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Steelers-Colts same-game parlay picks made 11/28/2022 at 2:06 p.m. ET.