Saints vs. Rams Prediction, Picks & Best Bets: NFL Preseason Week 2 Odds
The Los Angeles Rams host the New Orleans Saints on Saturday afternoon as part of Week 2 of the NFL preseason. My Saints vs. Rams prediction includes targeting a New Orleans offense that rolled in the first half last week, aided by an ongoing backup quarterback competition.
Kickoff is set for 4 p.m. ET on Saturday from SoFi Stadium in Inglewood, Calif. (ESPN Unlimited), with the Saints priced as a 2.5 to 3.5-point road betting favorite.
π Saints vs. Rams prediction: NFL preseason Week 2
See the latest NFL odds and our experts' NFL picks for every game this season.
| π° Pick | βοΈ Units | π§ Why I bet this |
|---|---|---|
| Saints -2.5 (-122 via FanDuel) | 0.4u β 0.33u | No team values preseason results less than the Rams. |
| Over 37.5 (-105 via DraftKings) | 0.6u β 0.57u | Saints' active QB2 competition will lead to higher scoring. |
Total wagered: 1 unit | Max profit: 0.9 units
π° Saints vs. Rams best bet
Over 37.5 (-105)
Active quarterback competitions usually lead to higher-scoring preseason games. That's why I'm targeting the Over here, as Spencer Rattler and Zach Wilson battle it out this August for the Saints' QB2 job.
Both quarterbacked the New Orleans offense efficiently last week against the Jacksonville Jaguars, each leading a touchdown drive as the Saints piled up 20 first-half points. Saturday's snaps will be valuable for Rattler and Wilson, and I expect them to make the most of them against Rams defensive backups who won't throw any complicated looks at them. DraftKings offers the best price on this total at -105.
Score prediction: Saints 23, Rams 16
π Saints vs. Rams same-game parlay
I put together a 2-leg parlay for Saints vs. Rams, combining Over 37.5 with New Orleans covering the -0.5 first-half spread. The Saints put up 20 points across the opening two quarters last week. I'm banking on Rattler and Wilson leading multiple scoring drives in the first half to put the Saints ahead at halftime and put us well on our way to cashing the full-game Over.
💵 Saints vs. Rams SGP picks
- Over 37.5
- Saints lead at halftime
Best odds: +281 via DraftKings (0.2u β 0.56u)
π΅ My betting record for NFL picks
All NFL preseason picks, including SGPs, have been tracked since Aug. 7.
| Bet type | Record | Net profit | ROI |
|---|---|---|---|
| Overall | 6-5 | +0.57 units β | 14.25% β |
| Game picks | 5-5 | +0.32 units β | 8.89% β |
| Player props | 1-0 | +0.25 units β | 62.5% β |
π‘ How I'm betting Saints vs. Rams: NFL preseason strategy
Follow all of our NFL analysis and betting advice for the 2026 NFL season.
Itβs important not to get carried away with your bet sizes in the preseason. Iβm only betting one unit total across my two favorite wagers for Saints vs. Rams because there is so much uncertainty in the preseason surrounding player snap counts, play-calling, and other variables. My most confident play (Over 37.5) received the highest wager at 0.6 units, slightly above my other best bet. Bankroll management is crucial in sports betting, so be smart with yours.
π Saints vs. Rams odds: NFL preseason Week 2
Our live Saints vs. Rams odds update in real time.
π Saints vs. Rams latest injuries
πΊ How to watch Saints vs. Rams: NFL preseason Week 2
- Date: Saturday, Aug. 22
- Kickoff: 4 p.m. ET
- Location: SoFi Stadium (Inglewood, Calif.)
- Streaming: ESPN Unlimited
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