NFL Parlay Picks, Predictions for Saturday: All Aboard the Home Favorites

The NFL Week 15 slate features three Saturday matchups loaded with both star power and playoff implications. Here are our tripleheader parlay picks based on the odds for the action.

The Saturday trifecta begins with the Minnesota Vikings looking to clinch the NFC North with a home victory over the Indianapolis Colts, and it concludes with a divisional showdown between the Miami Dolphins and Buffalo Bills in forecasted freezing and snowy conditions at Highmark Stadium.

The middle matchup features Cleveland Browns quarterback Deshaun Watson making his home debut with his team's playoff hopes on the line against the visiting Baltimore Ravens in another bout between divisional rivals.

Here are our best NFL parlay picks for Saturday (odds via PointsBet; pick confidence based on a 1-to-5-star scale).

  Check out our NFL best bets and all of our top NFL picks for Week 15.  

NFL Parlay Picks for Saturday

• Vikings -3.5 (-107 via PointsBet) ⭐⭐⭐
• Browns -2.5 (-105 via PointsBet) ⭐⭐
• Bills -7 (-107 via PointsBet) ⭐⭐⭐⭐

Combined odds: +630

NFL Parlay Predictions

Vikings -3.5 (-107) ⭐⭐⭐

Minnesota has weaknesses that prevent it from projecting as a legitimate playoff threat at this point. The VIkings are still 10-3, though, and they’ve bounced back with victories following each of their three losses. I’m expecting another rebound showing at home against the Indianapolis Colts on Saturday.

The Vikings have faced the third-hardest schedule by DVOA per Football Outsiders, and the Colts represent a significant downgrade in class. Indy has scored the second-fewest points per game (16.1) and rank 32nd in offensive DVOA and 31st in EPA per play.

I have this game power ranked as Minnesota -4, and I also value the superior offense playing at home. Additionally, this spread is now below the key number of 4 and two points below the -5.5 that was available in look-ahead markets. 

Check out our Colts-Vikings best bet.

Browns -3 (-105) ⭐⭐

With two starts under his belt, I’m expecting Watson to take another step forward in this must-win divisional matchup. 

I'm also encouraged that the Browns have won their past two home games, and their two-highest defense grades per PFF since Week 1 were in those matchups against the Cincinnati Bengals and Tampa Bay Buccaneers. 

Additionally, I don’t like this schedule spot for the Ravens. This will be the second consecutive road game for Baltimore and the third in four weeks. It will also be the first professional start in high winds and freezing temperatures for Ravens quarterback Tyler Huntley. 

I’m backing the better and more experienced quarterback in what projects as a close, low-scoring game.

Bills -7 (-107) ⭐⭐⭐

Give me the consensus betting favorite to win the Super Bowl at home on a short week in weather conditions forecasting snow squalls, freezing temperatures and wind gusts as high as 22 mph – especially with this lining up as a horrible schedule spot for Miami.

Following consecutive road losses, the Dolphins hit the highway for a third consecutive week, and quarterback Tua Tagovailoa is coming off back-to-back underwhelming showings. The Miami defense was also on the field for just north of 80 minutes over its past two games.

There are too many warning signs for the Dolphins, and a fifth straight Bills win seals a postseason berth for the home side. I’m confident in Buffalo winning comfortably, too.

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NFL parlay picks for Saturday made 12/16/2022 at 3:30 p.m. ET.