Yankees vs. Blue Jays Prediction, Odds & Best Bets: Can Toronto Get Back on Track?

New York spoiled Toronto's celebration on Tuesday, but can the Blue Jays get back to winning ways tonight?

Gabe Henderson

Last Updated: July 23, 2025 3:15 PM EDT • 4 minute read

Yankees vs. Blue Jays Prediction, Odds & Best Bets: Wednesday, July 23 — Pictured: Toronto Blue Jays starting pitcher Chris Bassitt (40) pitches to the New York Yankees as we make our Yankees vs. Blue Jays prediction. Photo by John E. Sokolowski via Imagn Images.

New York ended Toronto's franchise-record home winning streak on Tuesday, but my Yankees vs. Blue Jays prediction expects the hosts to get back on track during the rubber match.

The best sports betting sites list the Yankees as -135 betting favorites behind Cy Young Award odds contender Max Fried. However, Dustin Saracini expects New York's starter to struggle in his best strikeout props today.

First pitch from Rogers Centre in Toronto is set for 7:07 p.m. ET (Amazon Prime Video). My Yankees vs. Blue Jays best bets look to another visiting hitter to stay hot against the host's starter, despite Toronto getting back into the win column.

Yankees vs. Blue Jays prediction: Blue Jays to win (+122 via FanDuel) ⭐⭐⭐
Best Yankees vs. Blue Jays player props: Jasson Dominguez 2+ hits (+310 via FanDuel) ⭐⭐⭐

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✅ Yankees vs. Blue Jays prediction: Blue Jays to win (+122 via FanDuel)

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My Yankees vs. Blue Jays prediction fades both the oddsmakers and public - who are on New York ML at a 66% clip, according to BetMGM - as we believe Chris Bassitt will get the better of Max Fried today.

The latter struggled in his last outing in Canada, giving up four runs and three walks while striking out just two across six frames. The former has been lights out when pitching with home-field advantage, posting a 7-0 record and 2.53 ERA in 11 starts.

It's been over a month since the last time Toronto dropped back-to-back battles at Rogers Centre. The Blue Jays (36-17) only trail the Mets (36-16) for the best record in baseball at home, whereas the Yankees (26-26) are hit-or-miss on the road.

My Yankees vs. Blue Jays best bet recommends taking Toronto to win outright at three-star confidence. A $10 wager at our best sports betting apps pays out $12.20 if the Blue Jays can get back into the win column against their bitter AL East rivals.

💰 Best Yankees vs. Blue Jays player props

✅ Best Yankees vs. Blue Jays player prop: Jasson Dominguez 2+ hits (+310 via FanDuel)

It's no secret Jasson Dominguez is in the midst of a slump. His batting average has plummeted from .271 on July 4 to .254 heading into tonight's divisional duel. However, trends tell us that his hits come in bunches, and if there's a pitcher he'll break out against, it's Bassitt.

My best Yankees vs. Blue Jays player prop expects Dominguez to tally a pair of hits tonight. He's cashing this prop at a 30% clip over his last 10, but his career stats against Toronto's starter give us confidence betting on him will pay off tonight.

Dominguez has faced Bassitt six times in his career, registering five hits in that span. Even though it's a minuscule sample size, an .833 batting average is nothing to brush off. The best sportsbooks offer this play at value, considering trends suggest the odds should be closer to +233.

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Written by:
Gabe Henderson

Gabe Henderson is a sports betting writer from Houston, Texas. He graduated from Louisiana State University in 2022 with a bachelor's degree in Mass Communication. Gabe developed an interest in sports betting while in college due to its legalization in Louisiana. He turned his passion into a career shortly after, joining The Advocate/NOLA.com as a Sports Betting Content Coordinator, where he spent two years. Gabe wore many hats before graduating as he led FanSided's coverage of Chelsea FC as a Site Expert with "The Pride of London." He was also the Editor-in-Chief of the LSU Gumbo Yearbook for two years. Gabe became a part of the SportsbookReview.com team in late 2024. He brings with him an extensive knowledge of many sports, including — but not limited to — NFL, NCAA, MLB, NBA, soccer, and UFC.