Red Sox vs. Yankees Prediction Today: Best Bets & Odds for Boston vs. New York

Can the red-hot Roman Anthony lead the Red Sox to another victory inside the rowdy Yankee Stadium?

Mike Spector

Last Updated: August 23, 2025 11:31 AM EDT • 4 minute read

Red Sox vs. Yankees Prediction Today: Best Bets & Odds for Saturday, Aug. 23 — Pictured: Boston Red Sox third baseman Alex Bregman (2) celebrates with left fielder Roman Anthony (19) as I make my Red Sox vs. Yankees prediction. Photo by Troy Taormina via Imagn Images.

Boston has taken seven of eight from New York in this season's series to date, and my Red Sox vs. Yankees prediction backs the visitors to make it eight straight against their division rivals tonight.

The best sports betting sites list Boston as a -130 betting favorite, with a total set at O/U 8.5 runs. First pitch from Yankee Stadium in the Bronx, N.Y., is slated for 1:05 p.m. ET (MLB Network), as these American League East foes get the MLB spotlight to themselves in this timeslot.

I am adding one of the road team's top young sluggers to my Red Sox vs. Yankees best bets, as well.

⚾ Red Sox vs. Yankees prediction & odds

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💰 Red Sox vs. Yankees prediction & best bet

✅ Red Sox vs. Yankees prediction: Red Sox to win (-125 via Caesars)

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Garrett Crochet has been a mixed bag in his two prior starts against New York this season, whereas Boston's bats have punished the pinstripes for 5.9 runs per game across the last seven meetings. Thus, the Red Sox's offense gives me more confidence, and my Red Sox vs. Yankees prediction backs the hitters in case Crochet doesn't have his best stuff.

New York made history this week as the first team ever to record multiple games in a season with nine-plus home runs. However, Crochet should neutralize that power - even though the Yankees have the highest team OPS against southpaws - as he has not allowed a home run in six of his previous 10 starts.

Crochet has the third-highest strikeout rate and also ranks top five in xERA and FIP among all qualified pitchers. He has benefitted from extra rest of late, as he made seven of his first 16 starts through June 18 on four days' rest, but none since. As a result of that, and throwing the pitch at a season-low 27.7% clip in August, his fastball velocity is up to 97.1 mph this month, his highest of the year.

Boston’s moneyline is my Red Sox vs. Yankees best bet, despite losing each of Crochet’s last two starts, as the team is still 10-3 in his 13 outings since the start of June. I am making this wager at Caesars, as the Red Sox have as high as a 57.45% implied probability through -135 odds elsewhere at the high end of the market.

📊 Live Red Sox vs. Yankees odds: Saturday, 1:05 p.m. ET

🧐 Red Sox vs. Yankees betting insights

The latest Red Sox vs. Yankees betting insights are via BetMGM as of Saturday morning.

Team	Run Line	Moneyline	Total
Red Sox	26% (-1.5, +140)	48% (-125)	63% (Over 8, -118)
Yankees	74% (+1.5, -170)	52% (+105)	37% (Under 8, -102)

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💰 Best Red Sox vs. Yankees player prop

✅ Best Red Sox vs. Yankees player prop: Roman Anthony Over 1.5 total bases (+140 via bet365)

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Roman Anthony is one of only two players (Juan Soto) to rank in the 95th percentile or better in chase percentage and hard-hit rate. His plate discipline and hard contact make him the focus of my best Red Sox vs. Yankees player props.

Between June 21 and Aug. 22, Anthony batted .318 with four home runs, 21 RBI, and a .921 OPS over those 49 games. He reveled in his Yankee Stadium debut on Thursday, homering and driving in three runs.

These are great odds considering Anthony has gone Over this projected total in eight of the last 13 games, and did so the hard way with six multi-hit outings in that span. A $10 winning wager nets $14 in profits, which is $1 more than the other best sports betting apps offer with their +130 odds.

💡 Expert MLB predictions today

❓MLB betting FAQs

How do betting odds work?

Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common.

What is the run line in baseball?

The run line in baseball is a form of point spread betting unique to MLB. It typically sets a standard spread of 1.5 runs, meaning the favored team must win by at least two runs to cover the run line, while the underdog can lose by one run or win outright to cover.

What does moneyline mean in betting?

The moneyline in betting refers to a wager on which team or player will win the game outright, with no point spread involved. It’s the most straightforward type of sports bet - just pick the winner.

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Written by:
Mike Spector

Mike started in the sports writing industry in July 2019, and gained a lot of followers in his first year after finishing with the No. 2 overall record in an annual NFL betting competition, which made picks against the spread, and from an Over/Under and moneyline perspective. Mike is an avid fan of the NFL, MLB, tennis, and all college sports. In his opinion, March Madness is the best sporting event there is, and he's especially euphoric starting with conference tournament time in college basketball. Mike's a big advocate of "fading the public" and making plays that are contrarian, constantly citing that "there are reasons why they have those big shiny buildings in Las Vegas." When making wagers, Mike always scours the best odds at all of the major sports betting sites, where he mostly sifts through DraftKings, FanDuel, BetMGM, and bet365. He's tried several others and is of the firm belief that bettors should not just stick to one sportsbook, as there is always likely better value to be had with the same wager. In addition, while Mike received his undergraduate degree from Villanova University, he has no issue betting against the Wildcats when it comes to college basketball wagering, and suggests other bettors should always put their “head” before their “hearts.”