Padres vs. Dodgers Predictions, Odds & Best Bets: Clayton Kershaw Sits Down San Diego

San Diego has strung together five consecutive victories, but my Padres vs. Dodgers predictions expect Los Angeles to put a stop to the winning streak behind Clayton Kershaw.

First pitch is scheduled for 10:10 p.m. ET (MLB Network) from Dodger Stadium in Los Angeles. The best MLB betting sites list the Dodgers as -182 betting favorites, with a total set at O/U 9.5 runs.

My Padres vs. Dodgers best bets believe Kershaw is a difference-maker, despite Manny Machado's best efforts against his former team turned division foe.

⚾ Padres vs. Dodgers predictions & odds

🔎 Our NEW MLB player prop odds tool can help you find the best MLB odds to make your MLB picks.

📊 Live Padres vs. Dodgers odds: Friday, 10:10 p.m. ET

💰 Padres vs. Dodgers prediction & best bet

✅ Padres vs. Dodgers prediction: Dodgers to win (-182 via DraftKings)

Bet $5, Get $200 in Bonus Bets + Over $200 Off NFL Sunday Ticket

21+ and present in most states. (18+ DC/KY/NH/WY). Void in OR/NH. 1 per customer. $5+ first-time bet req. Get promo code to redeem NFL Sunday Ticket sub and max. $200 issued as non-withdrawable bonus bets; 7 day expiry.

Claim $400

These teams couldn't be trending in more opposite directions if they tried. San Diego comes into this series on the back of five straight wins, whereas Los Angeles was swept by its cross-town counterpart to extend their skid to four games. However, my Padres vs. Dodgers prediction sees me side with the best sports betting sites, which like L.A. in this spot.

The main reason I'm backing the Dodgers is because of the pitching advantage. Clayton Kershaw gets the nod for the hosts as he looks to extend his winning streak to three straight starts. He's owned San Diego historically, posting a 23-11 overall clip against the Padres across his 18-year career. Kershaw also has a 2.19 ERA against Los Angeles' fierce division rival.

The resurgence that the future Hall of Fame southpaw is experiencing right now has me as confident as ever in his ability. While Dave Roberts seems to be aboard a sinking ship right now, he's captained his crew to the calmer waters of Dodger Stadium for this pivotal series.

My Padres vs. Dodgers best bet backs Los Angeles at home, where it has been one of baseball's best teams at 38-24.

💰 Best Padres vs. Dodgers player prop

✅ Best Padres vs. Dodgers player prop: Manny Machado Over 0.5 singles (-105 via BetMGM)

Up To $1,500 First Bet

Bonus bets will expire in 7 days. One new customer offer only. Additional terms and conditions apply.

Claim $1,500

While I just gushed about Kershaw's renewed and refreshed form, my best Padres vs. Dodgers player prop backs one of San Diego's biggest stars to get a hit off the starter tonight.

Machado has a .310 career average (13-for-42) against his former favorite teammate, with eight of those hits being base knocks. He's in the midst of a four-game hitting streak that's seen him cash his Over 0.5 singles prop at a 75% clip. Machado has also cleared this total in five of his previous 10 appearances.

While this is a more specific market to play, the best sports betting apps offer more value here than on Machado Over 0.5 hits (-250). Bet this at BetMGM as opposed to DraftKings (-120), which has the shortest odds.

💡 Expert MLB predictions today

• MLB home run predictions
• Best NRFI bets today
• Brewers vs. Reds prediction
• Rangers vs. Blue Jays prediction
• Braves vs. Guardians prediction
• Mariners vs. Mets prediction
• Tigers vs. Twins prediction
• Padres vs. Dodgers prediction

(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.

Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.