Blue Jays vs. Yankees Prediction, Odds & Expert Picks: MLB Best Bets for Sept. 5
The Toronto Blue Jays and New York Yankees have frequently lit up the scoreboard in their head-to-head meetings this season, and I’m expecting more of the same for my Blue Jays vs. Yankees prediction. First pitch is set for 7:05 p.m. ET (Sportsnet, YES) on Friday night from Yankee Stadium in New York City.
My MLB picks like Blue Jays slugger Vladimir Guerrero Jr. to continue a recent hot stretch at the plate, and I’m targeting the Over on one of his player props to reflect that.
Be sure to also check out Mike Spector's best home run predictions today, which feature New York's Giancarlo Stanton alongside three other hitters.
⚾ Blue Jays vs. Yankees prediction
MLB expert picks made Friday; odds subject to change.
- Moneyline pick: Yankees (-130 via bet365) ⭐⭐⭐
- Run line pick: Yankees -1.5 (+165 via BetMGM) ⭐⭐
- Over/Under pick: Over 8.5 (-115 via BetMGM) ⭐⭐⭐⭐
📝 Blue Jays vs. Yankees preview & best bet
Track the latest MLB scores for line movement and matchup info.
🔥 Over 8.5 runs (-115) ⭐⭐⭐⭐
The Blue Jays and Yankees have been no strangers to high-scoring affairs in their meetings this season.
The two AL East rivals have soared past this total in seven of their 10 matchups so far in 2025. Yankee Stadium is ranked sixth on Baseball Savant’s Park Factors for venues that are most favorable to hit home runs this season.
Both teams have been red-hot at the plate as of late, with the Yankees averaging 7.5 runs per game over the last 10 and the Blue Jays putting up 6.7 runs per game over that same stretch.
One of the best sports betting sites, BetMGM, offered -115 odds on Over 8.5 runs, which nets a profit of $8.70 on a $10 bet. The -120 odds have an implied probability of 53.49%.
Up To $1,500 First Bet
Bonus bets will expire in 7 days. One new customer offer only. Additional terms and conditions apply.
Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.
💰 Best Blue Jays vs. Yankees player prop bet
Our MLB player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
⬆️ Vladimir Guerrero Jr. Over 1.5 hits, runs, and RBI (-125) ⭐⭐⭐
Vladimir Guerrero Jr. started to look like himself at the end of the Blue Jays’ recent series in Cincinnati, registering five hits, one home run, three RBI, and five runs scored over the final two games at Great American Ballpark.
The All-Star first baseman has destroyed fastballs this season, with 12 home runs, a .336 batting average, and a .543 slugging percentage. That could be a recipe for success against Yankees right-hander Cam Schlittler, who throws his fastball nearly 57% of the time.
Guerrero has always thrived in the hostile environment of Yankee Stadium in his career, with 15 home runs, 28 RBI, and a .957 OPS in 172 at-bats.
Backing Guerrero’s Over with a $10 wager pays out a profit of $8 at Caesars. The -125 odds have an implied probability of 55.56%.
Bet $1, Get Twenty 100% Profit Boosts
New users only. Must use promo code. Min. $10 deposit. Max. bonus is twenty 100% Profit Boost tokens. Profit Boost tokens expire in 14 days. Void where prohibited. Full terms.
Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.
📊 Blue Jays vs. Yankees odds: Sept. 5
MLB odds update live in real time.
📈 Blue Jays vs. Yankees betting odds analysis
New York opened as -136 favorites, with the line moving in both directions at some of the best sports betting apps. The Yankees are -130 favorites at some spots, but as high as -143 at others, as of Friday morning.
🔢 Blue Jays vs. Yankees stats
Season stats courtesy of baseball-reference.com.
| Blue Jays (81-59) | Statistic (per game) | Yankees (78-62) |
|---|---|---|
| 5.03 | Runs | 5.29 |
| 9.20 | Hits | 8.52 |
| .270 | AVG | .251 |
| .435 | SLG | .458 |
| .774 | OPS | .789 |
| 4.29 | ERA | 3.92 |
| 9.01 | K/9 | 9.07 |
| 3.19 | BB/9 | 3.52 |
| 1.37 | HR/9 | 1.10 |
🚑 Blue Jays vs. Yankees injuries
📺 Blue Jays vs. Yankees game info
- When: Friday, Sept. 5
- First pitch: 7:05 p.m. ET
- Where: Yankee Stadium (New York)
- How to watch: Sportsnet, YES
💡 Expert MLB predictions today
- MLB home run predictions today
- Nationals vs. Cubs prediction
- Blue Jays vs. Yankees prediction
❓ Blue Jays vs. Yankees FAQs
Who is favored to win Blue Jays vs. Yankees?
The Yankees are -130 favorites to defeat the Blue Jays at home on Friday.
What is the run line for Blue Jays vs. Yankees?
New York is a -1.5 run line favorite against Toronto in Friday’s matchup.
What is the Over/Under for Blue Jays vs. Yankees?
The total for Friday’s game between the Blue Jays and Yankees is 8.5.
What are the best bets for Blue Jays vs. Yankees?
My best bets for Friday’s Blue Jays vs. Yankees game are Over 8.5 runs (-115) and Vladimir Guerrero Jr. Over 1.5 hits, runs, and RBI. (-125).
When is the Blue Jays vs. Yankees game?
First pitch is set for 7:05 p.m. ET on Friday at Yankee Stadium.
How do baseball odds work?
When betting on MLB, the run line shows how many runs the favorite needs to win by in order to cash the bet. For example, a favorite of -1.5 must win by two or more runs to cover the run line, while an underdog at +1.5 must win outright or lose by one run to cover the run line.
Moneyline odds represent the payout for picking the outright winner (+200 means a $100 bet wins $200, while -200 means a $200 bet wins $100). Over/Unders let you wager on whether the combined total of runs will be higher or lower than the set number.
You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.
(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.
Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.
Related Articles
