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MLB Best Home Run Predictions Today: Best HR Props, Picks, Parlay & Odds (July 29)

My best home run predictions today break down the best HR bets for Wednesday's MLB slate.
Los Angeles Dodgers two-way player Shohei Ohtani (17) homers as we break down our home run predictions today.
Pictured: Los Angeles Dodgers two-way player Shohei Ohtani (17) homers as we break down our home run predictions today. Photo by William Liang / Imagn Images.
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We went 1-for-2 on our home run picks Tuesday, and we're looking to build on our 7.5% ROI in MLB this season. Our MLB home run predictions today feature Shohei Ohtani, Mike Trout, and Michael Busch on a loaded Wednesday slate.

My MLB home run picks target these hitters because they should be able to take advantage of favorable pitching matchups today.


⚾ Home run predictions today: MLB HR picks & odds July 29

See all of our experts’ MLB picks based on the latest MLB odds.

πŸ’£ Home run pick πŸ’΅ Units πŸ“ Notes
Shohei Ohtani to homer (+215 via FanDuel) 0.93u β†’ 2u Ohtani has a .683 xSLG vs. fastballs, which Hancock throws 77% of the time vs. LHH.
Mike Trout to homer (+320 via FanDuel) 0.63u β†’ 2u Wesneski threw 56% fastballs vs. RHH in 2025, and Trout has a .573 xSLG vs. fastballs.
Michael Busch to homer (+549 via DraftKings) 0.36u β†’ 2u Busch has a .485 xSLG vs. fastballs, May's go-to pitch vs. LHH.

Total wagered: 1.92 units | Max profit: 6 units

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πŸ’£ Best home run predictions & odds today

Home run pick: Shohei Ohtani (+215)

We cashed on Ohtani (+220) Tuesday night, and I'm going back to the well with him against Emerson Hancock today. Hancock throws fastballs 77% of the time to left-handed hitters, and Ohtani has a .683 xSLG against them.

The Dodgers' two-way star ranks fifth in MLB in Brls/PA% (10.2), so even though he has homered only once over his last 10 games, the analytics suggest he's still a good bet to hit for power moving forward. Ohtani to homer (+215) at FanDuel is the best line available among the top sports betting sites.

  • Time: 10:10 p.m. ET
  • Where to watch: MLB.TV

📡 SBR Edge: Home Cooking

Ohtani has homered in five of his last seven games at Dodger Stadium.


πŸ”₯ More home run predictions today

Home run pick: Mike Trout (+320)

Trout, Trout, Trout ... he hasn't homered in 15 straight games, but he has a great pitching matchup tonight to hit for power.

The Angels' star outfielder has a .573 xSLG against fastballs, which Hayden Wesneski threw 56% of the time to right-handed hitters in 2025 (he's making his season debut today).

Wesneski allowed 2.0 HR/9 in 2025, making him a strong candidate to give up a long ball today, and Trout is the favorite on the Angels to homer. Trout to homer (+320) at FanDuel is the best line available among the top sports betting apps.

  • Time: 9:38 p.m. ET
  • Where to watch: MLB.TV

Home run pick: Michael Busch (+549)

Dustin May has been somewhat lucky not to have allowed more home runs this season.

He ranks in the sixth percentile in hard-hit percentage (46.1) and the 17th percentile in average exit velocity (90.2). More importantly, he throws fastballs 62% of the time to left-handed hitters, and Busch has a .485 xSLG against them.

I understand why Pete Crow-Armstrong has shorter odds to homer tonight, but Busch's implied probability of 15.41% at these odds is definitely too low. Busch to homer (+549) at DraftKings is the best line available among the top MLB betting sites.

  • Time: 7:45 p.m. ET
  • Where to watch: MLB.TV

🤑 More MLB player props for Wednesday

Looking for more? Dive into Dustin Saracini's best NRFI bets today and best strikeout props today.


πŸ€‘ Most-bet home run hitters today

Betting insights via DraftKings.

Most-bet HR hitters (by handle)

  • Kyle Schwarber (Phillies)
  • Ronald Acuna Jr. (Braves)
  • Jackson Chourio (Brewers)

Most-bet HR hitters (by tickets)

  • James Wood (Nationals)
  • Kyle Schwarber (Phillies)
  • Esmerlyn Valdez (Pirates)

🎟️ Most-bet MLB player props today

Betting insights via BetMGM.

Player Team Bet Odds
Brooks Lee Twins To record 1+ total runs +140
Tarik Skubal Tigers To record 9+ K's +110
Cal Raleigh Mariners To record 1+ total runs +115
Nelson Velazquez Cardinals To hit 1+ home runs +600
Tarik Skubal Tigers To record 8+ K's -165

πŸš€ Best home run parlay picks today

💵 Best MLB home run parlay today

  • Shohei Ohtani to homer (+212)
  • Mike Trout to homer (+306)
  • Michael Busch to homer (+549)

Best odds: +8374 via DraftKings (0.05u -> 4.19u)


πŸ’΅ My betting record for MLB picks

All MLB picks, including SGPs, have been tracked since March 25.

Bet type Record Net profit ROI
Overall 9-20-2 +2.18 units βœ… 7.5% βœ…
Player props 6-13-1 +3.09 units βœ… 21.6% βœ…
Game props 2-2 -0.78 units βŒ -9.5% βŒ
Moneylines 1-1-1 +0.11 units βœ… 1.7% βœ…
Parlays 0-4 -0.25 units βŒ -100% βŒ