Best Home Run Predictions Today: MLB Odds, Picks & Prop Bets for Aug. 25

Brent Rooker and Tarik Skubal face off in a star-powered chess match tonight. Can the Athletics slugger overpower the Cy Young favorite?

Gabe Henderson

Last Updated: August 25, 2025 9:06 AM EDT • 4 minute read

Home Run Predictions Today: Best MLB Odds, Picks & Prop Bets for Aug. 25 — Pictured: Athletics left fielder Tyler Soderstrom (21) and designated hitter Brent Rooker (25) celebrate as I make my best home run predictions today. Photo by Steven Bisig via Imagn Images.

Mondays are a drag, but my best home run predictions today look to inject some excitement into the start of the week by offering up my favorite dinger picks.

Brent Rooker's chess match with Cy Young Award odds favorite Tarik Skubal is one to monitor. My home run bets today also eye established sluggers, such as Freddie Freeman, Kyle Schwarber, and Giancarlo Stanton, as they attempt to ascend the MLB home run charts.

If all four manage to leave the yard, a $10 parlay pays out over $3,000 in profits at the best MLB betting sites!

💰 MLB best home run predictions & odds today: Aug. 25

Here are my best MLB home run predictions and odds today with my pick confidence based on a 1-to-5-star scale. You can also check out our MLB player prop odds tool for the latest MLB odds at the best legal sportsbooks in your region.

🧨 Giancarlo Stanton to hit a home run (+325 via bet365) ⭐⭐⭐⭐
🧨 Kyle Schwarber to hit a home run (+265 via bet365) ⭐⭐⭐
🧨 Brent Rooker to hit a home run (+450 via bet365) ⭐⭐⭐⭐
🧨 Freddie Freeman to hit a home run (+420 via FanDuel) ⭐⭐⭐

🚀 Best home run parlay picks

Here is our best MLB home run parlay for Monday's baseball action; use our parlay calculator to get the best odds for any parlay.

💣 Giancarlo Stanton to hit a home run (+255 via FanDuel)
💣 Kyle Schwarber to hit a home run (+230 via FanDuel)
💣 Brent Rooker to hit a home run (+400 via FanDuel)
💣 Freddie Freeman to hit a home run (+420 via FanDuel)

Parlay odds: +30359 via FanDuel ($10 to win $3,035.90)

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💣 Best home run prediction today: MLB expert picks & prop bets

Here are my best home run bets today. Check out the rest of our MLB picks along with our guide on how to bet on MLB.

⚾ Brent Rooker (Athletics) to hit a home run ⭐⭐⭐⭐

Best odds: +450 via bet365 (bet $10 to win $45)

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Skubal owns one of the more impressive home run ratios in baseball, considering his hefty workload to date, which is why our Tigers vs. Athletics prediction is backing him to win tonight. He's given up just 13 long balls over 159 1/3 innings of work this season, an average of fewer than one per nine frames. However, while the rest of the league flounders trying to figure out Detroit's ace, Rooker has seemingly cracked the code.

The Athletics slugger is slashing .471/.500/1.000 in 17 career at-bats against Skubal. Three of his eight hits have left the yard, so could this be a great opportunity for Rooker to get back on track? He's only left the yard at a 20% clip in his last 10 starts, whereas Skubal has surrendered homers in three of his last four starts.

The best sports betting sites are offering a $45 return on a $10 winning wager, with bet365 leading the market with its +450 odds. Caesars and FanDuel come in on the low end, pricing this play at 4-1.

📊 Tigers vs. Athletics odds

💡 Expert MLB predictions today

❓Best home run predictions FAQs

What is a home run bet?

A home run bet is a wager on a hitter to hit a HR at any point during a game. Some sportsbooks allow you to bet on a hitter to not hit a home run, but the most common bet is on them to do so.

Can you parlay home run bets?

Yes, you can parlay home run bets. We've provided our best home run parlay today.

How do I place a home run bet?

To place a home run bet, simply go to your favorite sportsbook and go to the game featuring the player of your choice. Then click on batter props and you should see an option to bet a player to hit a home run.

What are the best home run props for tonight?

Our best home run predictions today feature Freddie Freeman, Brent Rooker, Kyle Schwarber, and Giancarlo Stanton.

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Written by:
Gabe Henderson

Gabe Henderson is a sports betting writer from Houston, Texas. He graduated from Louisiana State University in 2022 with a bachelor's degree in Mass Communication. Gabe developed an interest in sports betting while in college due to its legalization in Louisiana. He turned his passion into a career shortly after, joining The Advocate/NOLA.com as a Sports Betting Content Coordinator, where he spent two years. Gabe wore many hats before graduating as he led FanSided's coverage of Chelsea FC as a Site Expert with "The Pride of London." He was also the Editor-in-Chief of the LSU Gumbo Yearbook for two years. Gabe became a part of the SportsbookReview.com team in late 2024. He brings with him an extensive knowledge of many sports, including — but not limited to — NFL, NCAA, MLB, NBA, soccer, and UFC.