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Oklahoma Sooners defensive back Billy Bowman Jr. returns an interception as we give our Tennessee vs. Oklahoma early leans & predictions.
Oklahoma Sooners defensive back Billy Bowman Jr. returns an interception. Photo by: Bryan Terry/The Oklahoman/USA TODAY NETWORK via Imagn Images.

The No. 15 Oklahoma Sooners will make their SEC debut on Saturday when they host the No. 6 Tennessee Volunteers with kickoff set for 7:30 p.m. ET.

College GameDay will be in town to help set the stage for what should be the marquee matchup of Week 4 between two teams priced among the contenders in the latest college football championship odds.

Both teams carry 3-0 records into this week’s showdown and are eager to make a statement on the national stage.

As part of our Week 4 college football predictions, our Tennessee vs. Oklahoma early picks help prepare you for this weekend’s action.

My early Tennessee vs. Oklahoma prediction

College football picks made Tuesday; odds subject to change. Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Prediction: Oklahoma +7

Best odds: -105 via BetMGM | Implied probability: 51.22%

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All signs are pointing toward the Volunteers in this one. Tennessee has looked like a juggernaut through three weeks, covering the spread in all three games and outscoring its opponents by a 191-13 margin.

Oklahoma, meanwhile, labored through a 16-12 win against Houston in Week 2 before securing a 34-19 victory over Tulane last weekend.

But winning by more than a touchdown in a tough environment against a good team can be difficult. That’s why the our best sports betting apps had this line as Tennessee -3 in the lookahead market over the summer.

If this line climbs past the key number, I will likely have a Sooners ticket. This will be Tennessee’s toughest test yet.

Don't miss our guide for how to bet on college football or this week's best sportsbook promos.

Tennessee vs. Oklahoma live odds

See the college football odds from our best college football betting sites for every Week 4 game.

Moneyline

The betting odds will likely continue to move in Tennessee’s favor, especially with College Football Insiders projecting a fair outright price of 82% for the road team.

Our best sportsbooks charge as much as -297 for bettors to back the Volunteers on the moneyline.

Spread

FanDuel is the lone shop offering a spread below the key number, and the -122 vig is actually better value than the -115 price on the 7-point line.

Using Unabated’s line calculator tool, bettors would need -108 vig to justify passing the opportunity to lay below a touchdown.

Over/Under

The market has reached a consensus total of 57.5 after opening at 58.5. DraftKings offers the best value for those looking to chase the steam on the Under, thanks to its -108 price tag on the bet.

How to watch Tennessee vs. Oklahoma

  • When: Saturday, Sept. 21
  • Kickoff: 7:30 p.m. ET
  • Where: Gaylord Family Oklahoma Memorial Stadium (Norman, Okla.)
  • How to watch: TV
  • Weather: 84 degrees, 10% chance of precipitation, 11 mph S winds
  • Favorite: Tennessee -7 (-115 via BetMGM)

College football odds pages

Here are our best college football betting sites:

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