Indiana vs. Michigan State Picks, Predictions College Football Week 12: Can Spartans Keep Streak Alive?
The Michigan State Spartans managed to stop the ranked Illinois Fighting Illini and made it back-to-back wins against Rutgers last week. Can they notch a six-win season with a victory against Indiana? Read on for our top Indiana-Michigan State college football picks.
After falling into a losing slump, Michigan State got on track with back-to-back wins over Big Ten opponents. The Spartans will look for a third victory against a 3-7 Indiana team.
Here are our top picks for Indiana-Michigan State (odds via DraftKings Sportsbook and FanDuel Sportsbook; pick confidence based on a 1-to-5-star scale).
Check out all of our top college football picks for Week 12.
Indiana vs. Michigan State Odds
Indiana vs. Michigan State Picks
Indiana vs. Michigan State ATS Pick
Michigan State -10.5 (-106) ★★★★
After starting the season on a three-game winning streak, Indiana has suffered seven straight losses. The Hoosiers' lone win of the season over a Big Ten opponent was in Week 1 against Illinois. Indiana has come within 10.5 points of its opponent just twice in the seven losses.
Indiana is 0-6 against the spread in its last six road games, while Michigan State is 8-3-2 against the spread in its last 13 home games.
MSU quarterback Payton Thorne has thrown for 215 or more yards in three of his last four games, and tossing two touchdowns in three of those four games as well. The Spartans will rely heavily on their passing game to widen the gap against Indiana.
Indiana vs. Michigan State O/U Pick
Over 47.5 (-115) ★★★
Michigan State combined with its opponent for exactly 48 points in each of its last two games, and Indiana’s defense leaves the door open for more points to be scored in Week 12.
The Hoosiers are allowing 34.6 points per game on average and have allowed Big Ten opponents to score 38 or more points in three of their last four games.
With Michigan State’s offense scoring at least 23 points in each of its last game – while still allowing at least 15 points in five straight games – the Over has a big opportunity to hit.
Indiana vs. Michigan State Prop Pick
Reed Over 0.5 receiving touchdowns (+125) ★★★★
Michigan State receiver Jayden Reed has had a touchdown in five of his last six games, all against Big Ten opponents. Only once in the last six games has Reed recorded fewer than 60 yards.
Receiver Keon Coleman may lead the Spartans in receiving yards and touchdowns, but he has been held to just one touchdown across Michigan State’s last three games.
Reed has more receptions than Coleman in the Spartans’ last two games and will be a top target for Thorne against an Indiana team giving up 270 passing yards per game.
Where to Bet on Indiana vs. Michigan State Picks
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Indiana-Michigan State picks made 11/17/2022 at 3:20 p.m. ET.