NFL Odds Week 8: Lines, Spreads & Totals for Every Game
Last Updated: October 23, 2025 7:58 AM EDT • 2 minute read X Social Google News Link
📊 NFL odds Week 8, 2025
The NFL odds for Week 8 are via bet365.
| Game | Spread | Moneyline | Over/Under |
|---|---|---|---|
| Vikings vs. Chargers (TNF) | Chargers -3.5 | Vikings +155 / Chargers -185 | 44.5 (-110/-110) |
| Bills vs. Panthers | Panthers +7 | Bills -390 / Panthers +310 | 46 (-110/-110) |
| Bears vs. Ravens | Ravens -6.5 | Bears +230 / Ravens -280 | 49 (-110/-110) |
| Browns vs. Patriots | Patriots -7 | Browns +280 / Patriots -360 | 40.5 (-110/-110) |
| Dolphins vs. Falcons | Falcons -7.5 | Dolphins +325 / Falcons -425 | 44.5 (-110/-110) |
| Giants vs. Eagles | Eagles -7.5 | Giants +325 / Eagles -425 | 44 (-110/-110) |
| Jets vs. Bengals | Bengals -6.5 | Jets +235 / Bengals -290 | 44.5 (-110/-110) |
| 49ers vs. Texans | Texans -1.5 | 49ers +105 / Texans -125 | 41.5 (-110/-110) |
| Buccaneers vs. Saints | Saints +4 | Buccaneers -220 / Saints +180 | 47 (-110/-110) |
| Cowboys vs. Broncos | Broncos -3.5 | Cowboys +145 / Broncos -170 | 50.5 (-110/-100) |
| Titans vs. Colts | Colts -14 | Titans +750 / Colts -1200 | 47 (-110/-110) |
| Packers vs. Steelers (SNF) | Steelers +3 | Packers -170 / Steelers +145 | 45 (-110/-110) |
| Commanders vs. Chiefs (MNF) | Chiefs -12.5 | Commanders +550 / Chiefs -800 | 47 (-110/-110) |
Our NFL picks are loaded up ahead of tonight's Thursday Night Football tilt.
- The Thursday Night Football odds have the Chargers as a 3.5-point betting favorite over the visiting Vikings (8:15 p.m. ET, Prime Video)
- Sunday's action wraps with the Steelers hosting the Packers, and the Sunday Night Football odds have Green Bay as a 3-point betting favorite (8:20 p.m. ET, NBC)
- There's just one game featured in the Monday Night Football odds, with the Chiefs a 12.5-point home betting favorite over the Commanders (8:15 p.m. ET, ABC/ESPN)
- Six teams are on a bye, with the Detroit Lions, Las Vegas Raiders, Los Angeles Rams, Arizona Cardinals, Seattle Seahawks, and Jacksonville Jaguars all on the sidelines.
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📈 Week 8 biggest line movement
🔃 Biggest changes to the Week 8 lines
- The Dolphins looked flat in a 31-6 loss to Cleveland, and the Falcons' spread lengthened from -5.5 to -7
- Bengals went from -2.5 to -6.5 vs. the Jets, based on a surprise TNF victory over the Steelers combined with the Jets losing 13-6 and QB Justin Fields being benched
- The Broncos went from -5 to -3.5 vs. the Cowboys as they needed an incredible comeback to beat the Giants 33-32 after falling in a 19-0 hole
- The total moved from 47.5 to 50.5
- The Colts went from -11.5 to -14 vs. the Titans following a huge performance in Los Angeles against the Chargers, winning 38-24
- The total grew from 45 to 47
- The Chiefs grew from -5.5 to -12.5 against the Commanders following confirmation that Jayden Daniels wouldn't be under center
- The total fell from 50.5 to 46.5
🚑 Injuries to monitor
🚑️ Injuries to monitor for Week 8
- Commanders QB Jayden Daniels will miss this game after suffering an injury last week, an injury that was partially baked into the line already
- Ravens QB Lamar Jackson appears set to return to action against the Bears
- Bucs WR Mike Evans returned from injury to suffer a broken collarbone; WR Chris Godwin's status remains up in the air following back-to-back missed games
- Texans WR Nico Collins suffered a concussion and his status remains unknown for this week
- Panthers QB Bryce Young left with an ankle sprain and is expected to be out this week
- Falcons QB Michael Penix Jr. is day-to-day with a bruised foot, his status for the weekend is unknown
- Raiders DE Maxx Crosby was removed and didn't return to action, but is expected to be okay going forward
- Giants S Jevon Holland and CB Paulson Adebo both left and didn't return with knee injuries
- TItans DT Jeffrey Simmons and CB L'Jarius Sneed were forced out with injury and didn't return
🏈 Vikings vs. Chargers odds: Thursday Night Football
- Kickoff: 8:15 p.m. ET from SoFi Stadium (Inglewood, Calif.)
- How to watch: Prime Video
- Vikings vs. Chargers prediction
🏈 Packers vs. Steelers odds: Sunday Night Football
- Kickoff: 8:20 p.m. ET from Acrisure Stadium (Pittsburgh)
- How to watch: NBC'
- Early Packers vs. Steelers prediction
🏈 Commanders vs. Chiefs odds: Monday Night Football
- Kickoff: 8:15 p.m. ET from GEHA Field at Arrowhead Stadium (Kansas City, Mo.)
- How to watch: ESPN/ABC
- Early Commanders vs. Chiefs prediction
🔢 NFL Week 8 odds and lines
There's an advantage to betting early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your NFL picks, the harder it becomes to identify edges and secure the best price on most sides or totals.
❓Who's playing on prime time in Week 8?
Week 8 opens with the Chargers hosting the Vikings on Thursday Night Football. Sunday wraps with the Packers and Steelers on Sunday Night Football, and just one Monday Night Football game in Week 8, with the Commanders visiting the Chiefs.
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