NFL Odds: Lines, Spreads & Totals for Every Week 7 Game

We look at the NFL odds and Week 7 lines & spreads, focusing on the biggest line movements and impact injuries moving lines.
NFL Odds: Lines, Spreads & Totals for Every Week 7 Game
Pictured: Tampa Bay Buccaneers wide receiver Tez Johnson (15). Photo by Jonathan Dyer-Imagn Images
Enjoying SBR content? Add us as a preferred source on your Google account Add as a preferred source on Google

📊 NFL odds Week 7, 2025

The NFL odds for Week 7 are via bet365.

Game Spread  Moneyline Over/Under
Steelers vs. Bengals (TNF) Bengals +5.5 Steelers -260 / Bengals +210 42.5 (-110/-110)
Rams vs. Jaguars (London) Jaguars +3 Rams -160 / Jaguars +135 45 (-110/-110)
Panthers vs. Jets Jets +1.5 Panthers -130 / Jets +10 42 (-110/-110)
Raiders vs. Chiefs Chiefs -12 Raiders +525 / Chiefs -750 45.5 (-110/-110)
Dolphins vs. Browns Browns -2.5 Dolphins +125 / Browns -150 40.5 (-110/-110)
Patriots vs. Titans Titans +7 Patriots -340 / Titans +270 42 (-110/-110)
Saints vs. Bears Bears -5.5 Saints +200 / Bears -245 46.5 (-110/-110)
Eagles vs. Vikings Vikings +2.5 Eagles -140 / Vikings +120 43.5 (-110/-110)
Colts vs. Chargers Chargers -1.5 Colts +105 / Chargers -125 48.5 (-110/-100)
Giants vs. Broncos Broncos -7 Giants +280 / Broncos -360 40.5 (-110/-110)
Packers vs. Cardinals Cardinals +6.5 Packers -310 / Cardinals +250 44.5 (-110/-110)
Commanders vs. Cowboys Cowboys +2.5 Commanders -130 / Cowboys +120 54.5 (-110/-110)
Falcons vs. 49ers (SNF) 49ers -3 Falcons +130 / 49ers -155 45.5 (-110/-110)
Buccaneers vs. Lions (MNF) Lions -4.5 Buccaneers +190 / Lions -230 53 (-110/-110)
Texans vs. Seahawks (MNF) Seahawks -3.5 Texans +155 / Seahawks -185 41 (-110/-110)

Our NFL picks are loaded up for another week, and we have 15 games to choose from with only the Buffalo Bills and Baltimore Ravens on a bye.

  • The Thursday Night Football odds highlight an AFC North rivalry, with the Steelers a 5.5-point road favorite at the Bengals (8:15 p.m. ET, Prime Video)
  • The league wraps up its London games on Sunday with the Rams a 3-point betting favorite at Wembley Stadium (9:30 a.m. ET, NFL Network)
  • The Falcons and 49ers clash to wrap up Sunday's action, with the Sunday Night Football odds showing the 49ers as the 3.5-point betting favorite (8:20 p.m. ET, NBC)
  • The Monday Night Football odds again treat us to a doubleheader:
    • The Lions are a 4.5-point home betting favorite against the visiting Buccaneers (7 p.m. ET, ABC/ESPN)
    • The Seahawks are a 3-point betting favorite as they host the Texans (10 p.m. ET, ESPN)
  • The week's biggest spread on Monday: Chiefs -12 vs. Raiders
  • The week's biggest total on Monday: 54.5 points for Commanders vs. Cowboys

👇️ See more SBR!

Want to make sure SBR shows up often in your Google search results and Discover feed? Simply click here and add Sportsbook Review as one of your "source preferences".

Bet $5, Get $150 in Bonus Bets Win or Lose*

*Deposit required. Mobile app only. Bonus Bets wager excluded from returns. T&Cs, time limits and exclusions apply. Gambling problem? Call 1-800-GAMBLER. Referral Codes are used for marketing/tracking purposes only.

Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.


📈  Week 7 biggest line movement

📈 The biggest changes to the Week 7 lines

  • An awful showing from the Jets (11 points in a loss to the Broncos) flipped them from -2.5 to +1.5 against the Panthers, and the total dropped from 44.5 to 42
  • The Broncos didn't show much better in that win over the Jets while scoring only 13 points, and they tightened from -8.5 to -7 vs. the Giants
  • The Cardinals came up short again, and Kyler Murray's status remains up in the air, moving them from +5 to +6.5
  • A long list of injuries have tightened the 49ers from -4.5 to -3 against the visiting Falcons
  • An injury to Puka Nacua and sputtering offenses (Rams 17, Jaguars 12) have resulted in the line dropping from 47 to 45

🚑 New injuries to monitor

🚑️ Key injuries suffered in Week 6

  • Arizona lost running back Emari Demercado (ankle) and wideout Marvin Harrison Jr. (concussion), and both status are unknown going forward
  • Cincinnati lost tight end Mike Gesicki to a pectoral injury that's expected to sideline him for an extended period
  • Cleveland tight end David Njoku left with a knee injury; his status is unknown
  • The Rams suffered a pair of ankle injuries, with Blake Corum and Puka Nacua both forced from action
  • New York Jets wideout Garrett Wilson suffered a knee injury and is expected to miss multiple weeks
  • The 49ers lost linebacker Fred Warner for the season after he suffered a broken and dislocated ankle
  • The Buccaneers are expecting to be without rookie WR Emeka Egbuka after he suffered a hamstring injury

🏈 Steelers vs. Bengals odds: Thursday Night Football

  • Kickoff: 8:15 p.m. ET from Paycor Stadium (Cincinnati)
  • How to watch: Prime Video

🏈 Rams vs. Jaguars odds: NFL London Game

  • Kickoff: 9:30 a.m. ET from Wembley Stadium (London)
  • How to watch: NFL Network

🏈 Falcons vs. 49ers odds: Sunday Night Football

  • Kickoff: 8:20 p.m. ET from Levi's Stadium (Santa Clara, Calif.)
  • How to watch: NBC

🏈 Buccaneers vs. Lions odds: Monday Night Football

  • Kickoff: 7 p.m. ET from Ford Field (Detroit)
  • How to watch: ESPN/ABC

🏈 Texans vs. Seahawks odds: Monday Night Football

  • Kickoff: 10 p.m. ET from Lumen Field (Seattle)
  • How to watch: ABC

🔢 NFL Week 7 odds and lines

There's an advantage to betting early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your NFL picks, the harder it becomes to identify edges and secure the best price on most sides or totals.

❓NFL odds FAQs

Who's playing on prime time in Week 7?

The week opens with the Steelers vs. Bengals on Thursday Night Football. Sunday features the third and final London game, with the Rams vs. Jaguars clash at Wembley Stadium. Sunday Night Football wraps up the day with the 49ers and Falcons. Another Monday Night Football doubleheader is on the docket, with the Buccaneers vs. the Lions and the Texans vs. the Seahawks.

How do NFL spread odds work?

When betting on the NFL, the favorite needs to win by a certain number of points to cover the "point spread" - also known as the betting line. Conversely, the underdog needs to lose by fewer than the points displayed in the spread or win outright to cash. For example, a 3-point favorite would need to win by more than a field goal to reward bettors.

How do NFL moneyline odds work?

When betting on the NFL, the underdog will have the "longer" odds and is typically priced at "plus-money" odds that indicate the profit on a $100 bet. For example, a team with +150 odds would turn a $100 bet into a $150 profit - or a $10 bet into a $15 profit - according to our odds converter.

Where can I find the NFL betting odds?

Shop around our best NFL betting sites to find the best odds for your college football picks. Our best sports betting sites for all sports include BetMGM, bet365, Caesars, FanDuel, and DraftKings.

📃 Affiliate disclosure

Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.

Not intended for use in MA. Bonuses not applicable in Ontario.

(21+. Gambling Problem? Call 1-800-GAMBLE)