NFL Odds Week 3: Lines, Spreads & Totals for Every Game
📊 NFL odds Week 3, 2025
The NFL odds for Week 3 are via bet365.
| Game | Spread | Moneyline | Over/Under |
|---|---|---|---|
| Dolphins vs. Bills (TNF) | Bills -9.5 | Dolphins +350 / Bills -450 | 48.5 (-110/-110) |
| Falcons vs. Panthers | Panthers +1.5 | Falcons -125 / Panthers +105 | 44.5 (-110/-110) |
| Bengals vs. Vikings | Vikings -1.5 | Bengals +100 / Vikings -120 | 46.5 (-110/-110) |
| Packers vs. Browns | Browns +6.5 | Packers -380 / Browns +300 | 43 (-110/-110) |
| Texans vs. Jaguars | Jaguars -1.5 | Texans +100 / Jaguars -120 | 43 (-110/-110) |
| Colts vs. Titans | Titans +1.5 | Colts -125 / Titans +105 | 43 (-110/-110) |
| Rams vs. Eagles | Eagles -4 | Rams +185 / Eagles -225 | 45 (-110/-110) |
| Raiders vs. Commanders | Commanders -6 | Raiders +240 / Commanders -300 | 47.5 (-110/-110) |
| Jets vs. Buccaneers | Buccaneers -5.5 | Jets +210 / Buccaneers -260 | 44.5 (-110/-100) |
| Steelers vs. Patriots | Patriots +1 | Steelers -115 / Patriots -105 | 43 (-110/-110) |
| Broncos vs. Chargers | Chargers -1.5 | Broncos +115 / Chargers -135 | 43.5 (-110/-110) |
| Saints vs. Seahawks | Seahawks -6 | Saints +245 / Seahawks -305 | 41.5 (-110/-110) |
| Cardinals vs. 49ers | 49ers -2.5 | Cardinals +125 / 49ers -150 | 44.5 (-110/-110) |
| Cowboys vs. Bears | Bears -1.5 | Cowboys +110 / Bears -130 | 46 (-110/-110) |
| Chiefs vs. Giants (SNF) | Giants +6 | Chiefs -260 / Giants +210 | 42.5 (-110/-110) |
| Lions vs. Ravens (MNF) | Ravens -6 | Lions +220 / Ravens -270 | 50.5 (-110/-110) |
Our NFL picks are piling up as the season presses on.
- An AFC East showdown is featured in the Thursday Night Football odds, but it doesn't look like a close game as the Bills are a 9.5-point betting favorite ahead of kickoff at 8:15 p.m. ET (Prime Video) on Sept. 18
- The Sunday Night Football odds aren't promising a close game, either, with the Chiefs a 6-point road betting favorite over the Giants at 8:20 p.m. ET (NBC)
- The Monday Night Football odds aren't any closer (Ravens -6 vs. Lions) but that could change if Detroit has a stronger Week 2 performance; kickoff in Baltimore is at 8:15 p.m. ET (ABC/ESPN) on Sept. 22
🏈 Dolphins vs. Bills odds: Thursday Night Football
- Kickoff: 8:15 p.m. ET from Highmark Stadium (Orchard Park, N.Y.)
- How to watch: Prime Video
🏈 Chiefs vs. Giants odds: Sunday Night Football
- Kickoff: 8:20 p.m. ET from MetLife Stadium (East Rutherford, N.J.)
- How to watch: NBC
🏈 Lions vs. Ravens odds: Monday Night Football
- Kickoff: 8:15 p.m. ET from M&T Bank Stadium (Baltimore)
- How to watch: ABC/ESPN
🔢 NFL Week 3 odds and lines
There's an advantage to betting early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your NFL picks, the harder it becomes to identify edges and secure the best price on most sides or totals.
❓NFL odds FAQs
Who's playing on prime time in Week 3?
The Miami Dolphins visit the Buffalo Bills for Thursday Night Football, the New York Giants host the Kansas City Chiefs for Sunday Night Football, and Monday Night Football features the Detroit Lions at Baltimore Ravens.
How do NFL spread odds work?
When betting on the NFL, the favorite needs to win by a certain number of points to cover the "point spread" - also known as the betting line. Conversely, the underdog needs to lose by fewer than the points displayed in the spread or win outright to cash. For example, a 3-point favorite would need to win by more than a field goal to reward bettors.
How do NFL moneyline odds work?
When betting on the NFL, the underdog will have the "longer" odds and is typically priced at "plus-money" odds that indicate the profit on a $100 bet. For example, a team with +150 odds would turn a $100 bet into a $150 profit - or a $10 bet into a $15 profit - according to our odds converter.
Where can I find the NFL betting odds?
Shop around our best NFL betting sites to find the best odds for your college football picks. Our best sports betting sites for all sports include BetMGM, bet365, Caesars, FanDuel, and DraftKings.
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