NFL Odds Week 13: Lines, Spreads & Totals for Every Thanksgiving Week Game

We look at the NFL odds and Week 13 lines & spreads, focusing on the biggest line movements and impact injuries moving the betting lines.
Tailgate Tom the turkey sits outside AT&T Stadium as we look at the Week 13 NFL odds.
Pictured: Tailgate Tom the turkey sits outside AT&T Stadium as we look at the Week 13 NFL odds. Photot by Tim Heitman-Imagn Images
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📊 NFL odds Week 13, 2025

The NFL odds for Week 13 are via bet365.

Game Spread  Moneyline Over/Under
Packers vs. Lions (Thanksgiving) Lions -3 GB +135 / DET -160 48.5
Chiefs vs. Cowboys (Thanksgiving) Cowboys +4 KC -190 / DAL +160 51.5
Bengals vs. Ravens (Thanksgiving) Ravens -10.5 CIN +500 / BAL -700 50
Bears vs. Eagles (TNF on Black Friday) Eagles -7 CHI +275 / PHI -350 45
Cardinals vs. Buccaneers Buccaneers -6.5 ARI +235 / TB -290 49.5
Falcons vs. Jets Jets +1.5 ATL -125 / NYJ +105 39.5
Texans vs. Colts Colts -4.5 HOU +170 / IND -205 46.5
Jaguars vs. Titans Titans +7 JAX -320 / TEN +260 42.5
Rams vs. Panthers Panthers +9.5 LAR -500 / CAR +375 45.5
Saints vs. Dolphins Dolphins -4.5 NO +170 / MIA -205 43
49ers vs. Browns Browns +6.5 SFO -305 / CLE +245 42.5
Vikings vs. Seahawks Seahawks -7.5 MIN +290 / SEA -370 43.5
Bills vs. Steelers Steelers +4.5 BUF -200 / PIT +165 47
Raiders vs. Chargers Chargers -8.5 LV +350 / LAC -450 42.5
Broncos vs. Commanders (SNF) Commanders +6.5 DEN -280 / WSH +230 43.5
Giants vs. Patriots (MNF) Patriots -7.5 NYG +290 / NE -370 46.5

Our NFL picks will be locked and loaded for Week 13, with three games on Thanksgiving and a TNF game on Black Friday. Bye weeks resume next week.

  • Thursday opens with three games instead of one, as Thanksgiving rules the day
    • The Lions are a 3-point home betting favorite over the Packers in a classic at Ford Field (1 p.m. ET, FOX)
    • The Chiefs are a 4-point road betting favorite as they visit the Cowboys at AT&T Stadium in Arlington, Texas (4:30 p.m. ET, CBS)
    • The Ravens are a 10.5-point home favorite in an AFC North rivalry clash at M&T Bank Stadium in Baltimore (8:20 p.m. ET, NBC)
  • The Thursday Night Football odds have the Eagles as a 7-point favorite against the visiting Bears at Lincoln Financial Field in Philadelphia on Black Friday (3 p.m. ET, Prime Video)
  • Sunday's action wraps with the Broncos as a 6.5-point road betting favorite against the Commanders at Northwest Stadium in Landover, Md., per the Sunday Night Football odds (8:20 p.m. ET, NBC)
  • One game in the Monday Night Football odds as the week wraps up, with the Patriots a 7.5-point home betting favorite against the visiting Giants at Gillette Stadium in Foxborough, Mass. (8:15 p.m. ET, ESPN)

We're continuing to monitor to the Week 12 NFL odds, and this week's results will surely impact the Week 13 odds.


🏈 Packers vs. Lions odds: Thanksgiving

  • Kickoff: 1 p.m. ET from Ford Field (Detroit)
  • How to watch: FOX

🏈 Chiefs vs. Cowboys: Thanksgiving

  • Kickoff: 4:30 p.m. ET from AT&T Stadium (Arlington, Texas)
  • How to watch: CBS

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🏈 Bengals vs. Ravens odds: Thanksgiving

  • Kickoff: 8:20 p.m. ET from M&T Bank Stadium (Baltimore)
  • How to watch: NBC

🏈 Bears vs. Eagles odds: Thursday Night Football on Black Friday

  • Kickoff: 3 p.m. ET from Lincoln Financial Field (Philadelphia)
  • How to watch: Prime Video

🏈 Broncos vs. Commanders odds: Sunday Night Football

  • Kickoff: 8:20 p.m. ET from Northwest Stadium (Landover, Md.)
  • How to watch: Prime Video

🏈 Giants vs. Patriots odds: Monday Night Football

  • Kickoff: 8:15 p.m. ET from Gillette Stadium (Foxborough, Mass.)
  • How to watch: ESPN

🔢 NFL Week 13 odds and lines

There's an advantage to betting early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your picks, the harder it becomes to identify edges and secure the best price on most sides or totals.

❓ Who's playing on prime time in Week 13?

Week 13 opens with a Thanksgiving triple-header, opening with the Packers vs. Lions. The day continues with the Cowboys hosting the Chiefs, and wraps with the Bengals and Ravens clashing. Our Thursday Night Football is actually on Black Friday and actually in the afternoon, as the Bears and Eagles meet. The Broncos and Commanders meet for a cross-conference battle on Sunday Night Football, while the Giants and Patriots meet to finish the week on Monday Night Football.


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