NFL Odds Week 13: Lines, Spreads & Totals for Every Thanksgiving Week Game
Last Updated: November 19, 2025 6:55 AM EST • 3 minute read X Social Google News Link
📊 NFL odds Week 13, 2025
The NFL odds for Week 13 are via bet365.
| Game | Spread | Moneyline | Over/Under |
|---|---|---|---|
| Packers vs. Lions (Thanksgiving) | Lions -3 | GB +135 / DET -160 | 48.5 |
| Chiefs vs. Cowboys (Thanksgiving) | Cowboys +4 | KC -190 / DAL +160 | 51.5 |
| Bengals vs. Ravens (Thanksgiving) | Ravens -10.5 | CIN +500 / BAL -700 | 50 |
| Bears vs. Eagles (TNF on Black Friday) | Eagles -7 | CHI +275 / PHI -350 | 45 |
| Cardinals vs. Buccaneers | Buccaneers -6.5 | ARI +235 / TB -290 | 49.5 |
| Falcons vs. Jets | Jets +1.5 | ATL -125 / NYJ +105 | 39.5 |
| Texans vs. Colts | Colts -4.5 | HOU +170 / IND -205 | 46.5 |
| Jaguars vs. Titans | Titans +7 | JAX -320 / TEN +260 | 42.5 |
| Rams vs. Panthers | Panthers +9.5 | LAR -500 / CAR +375 | 45.5 |
| Saints vs. Dolphins | Dolphins -4.5 | NO +170 / MIA -205 | 43 |
| 49ers vs. Browns | Browns +6.5 | SFO -305 / CLE +245 | 42.5 |
| Vikings vs. Seahawks | Seahawks -7.5 | MIN +290 / SEA -370 | 43.5 |
| Bills vs. Steelers | Steelers +4.5 | BUF -200 / PIT +165 | 47 |
| Raiders vs. Chargers | Chargers -8.5 | LV +350 / LAC -450 | 42.5 |
| Broncos vs. Commanders (SNF) | Commanders +6.5 | DEN -280 / WSH +230 | 43.5 |
| Giants vs. Patriots (MNF) | Patriots -7.5 | NYG +290 / NE -370 | 46.5 |
Our NFL picks will be locked and loaded for Week 13, with three games on Thanksgiving and a TNF game on Black Friday. Bye weeks resume next week.
- Thursday opens with three games instead of one, as Thanksgiving rules the day
- The Lions are a 3-point home betting favorite over the Packers in a classic at Ford Field (1 p.m. ET, FOX)
- The Chiefs are a 4-point road betting favorite as they visit the Cowboys at AT&T Stadium in Arlington, Texas (4:30 p.m. ET, CBS)
- The Ravens are a 10.5-point home favorite in an AFC North rivalry clash at M&T Bank Stadium in Baltimore (8:20 p.m. ET, NBC)
- The Thursday Night Football odds have the Eagles as a 7-point favorite against the visiting Bears at Lincoln Financial Field in Philadelphia on Black Friday (3 p.m. ET, Prime Video)
- Sunday's action wraps with the Broncos as a 6.5-point road betting favorite against the Commanders at Northwest Stadium in Landover, Md., per the Sunday Night Football odds (8:20 p.m. ET, NBC)
- One game in the Monday Night Football odds as the week wraps up, with the Patriots a 7.5-point home betting favorite against the visiting Giants at Gillette Stadium in Foxborough, Mass. (8:15 p.m. ET, ESPN)
We're continuing to monitor to the Week 12 NFL odds, and this week's results will surely impact the Week 13 odds.
🏈 Packers vs. Lions odds: Thanksgiving
- Kickoff: 1 p.m. ET from Ford Field (Detroit)
- How to watch: FOX
🏈 Chiefs vs. Cowboys: Thanksgiving
- Kickoff: 4:30 p.m. ET from AT&T Stadium (Arlington, Texas)
- How to watch: CBS
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🏈 Bengals vs. Ravens odds: Thanksgiving
- Kickoff: 8:20 p.m. ET from M&T Bank Stadium (Baltimore)
- How to watch: NBC
🏈 Bears vs. Eagles odds: Thursday Night Football on Black Friday
- Kickoff: 3 p.m. ET from Lincoln Financial Field (Philadelphia)
- How to watch: Prime Video
🏈 Broncos vs. Commanders odds: Sunday Night Football
- Kickoff: 8:20 p.m. ET from Northwest Stadium (Landover, Md.)
- How to watch: Prime Video
🏈 Giants vs. Patriots odds: Monday Night Football
- Kickoff: 8:15 p.m. ET from Gillette Stadium (Foxborough, Mass.)
- How to watch: ESPN
🔢 NFL Week 13 odds and lines
There's an advantage to betting early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your picks, the harder it becomes to identify edges and secure the best price on most sides or totals.
❓ Who's playing on prime time in Week 13?
Week 13 opens with a Thanksgiving triple-header, opening with the Packers vs. Lions. The day continues with the Cowboys hosting the Chiefs, and wraps with the Bengals and Ravens clashing. Our Thursday Night Football is actually on Black Friday and actually in the afternoon, as the Bears and Eagles meet. The Broncos and Commanders meet for a cross-conference battle on Sunday Night Football, while the Giants and Patriots meet to finish the week on Monday Night Football.
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Andrew Reid X social