NFL Odds Week 13: Betting Lines, Spreads, and Totals for Every Game

We look at the NFL odds and Week 13 lines & spreads, focusing on the biggest line movements and impact injuries moving the betting lines.
Jacksonville Jaguars wide receiver Jakobi Meyers celebrates after scoring a touchdown as we look at the Week 13 odds.
Pictured: Jacksonville Jaguars wide receiver Jakobi Meyers celebrates after scoring a touchdown as we look at the Week 13 odds. Photo by Mark J. Rebilas-Imagn Images
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📊 NFL odds Week 13, 2025

The NFL odds for Week 13 are via bet365.

Game Spread  Moneyline Over/Under
Packers 31, Lions 24 Lions -3 ❌ GB +135 / DET -160 48 ⬆️(55)
Cowboys 31, Chiefs 28 Cowboys +3 ✅ KC -185 / DAL +155 52.5 ⬆️ (59)
Bengals 32, Ravens 14 Ravens -7 ❌ CIN +290 / BAL -370 52 ⬇️ (46)
Bears vs. Eagles (TNF on Black Friday) Eagles -7 CHI +280 / PHI -360 43.5
Cardinals vs. Buccaneers Buccaneers -3.5 ARI +155 / TB -185 44.5
Falcons vs. Jets Jets +2.5 ATL -140 / NYJ +120 39.5
Texans vs. Colts Colts -3.5 HOU +160 / IND -190 44
Jaguars vs. Titans Titans +6 JAX -300 / TEN +240 41.5
Rams vs. Panthers Panthers +10 LAR -550 / CAR +400 44.5
Saints vs. Dolphins Dolphins -5.5 NO +220 / MIA -270 41.5
49ers vs. Browns Browns +4.5 SFO -240 / CLE +195 36.5
Vikings vs. Seahawks Seahawks -11.5 MIN +550 / SEA -800 41
Bills vs. Steelers Steelers +3 BUF -185 / PIT +155 45.5
Raiders vs. Chargers Chargers -9.5 LV +390 / LAC -525 40.5
Broncos vs. Commanders (SNF) Commanders +5.5 DEN -260 / WSH +210 43.5
Giants vs. Patriots (MNF) Patriots -7 NYG +275 / NE -350 46.5

Our NFL picks will be locked and loaded for Week 13, with three games on Thanksgiving and a TNF game on Black Friday. Bye weeks resume next week.

  • Thursday opened with three underdogs winning: the Packers (31-24 vs. Lions), the Cowboys (31-28 vs. Chiefs), and the Bengals (32-14 vs. Ravens)
  • The Thursday Night Football odds have the Eagles as a 7-point favorite against the visiting Bears at Lincoln Financial Field in Philadelphia on Black Friday (3 p.m. ET, Prime Video)
  • Sunday's action wraps with the Broncos as a 5.5-point road betting favorite against the Commanders at Northwest Stadium in Landover, Md., per the Sunday Night Football odds (8:20 p.m. ET, NBC)
  • One game in the Monday Night Football odds as the week wraps up, with the Patriots a 7-point home betting favorite against the visiting Giants at Gillette Stadium in Foxborough, Mass. (8:15 p.m. ET, ESPN)

📈  Week 13 biggest line movement

🔃 Biggest changes to the Week 13 lines

  • The Ravens have moved from -10.5 to -6.5 point favorites over the Bengals with the expectation that Cincinnati QB Joe Burrow should return to action on Thanksgiving
    • The total has also jumped from 50 to 51.5
    • The Ravens lost outright, 32-14
  • The Bucs have slipped from -6.5 to -3.5 against the Cardinals following QB Baker Mayfield's injury; the signal-caller's shoulder was injured and his status is up in the air
    • The total has slipped from 49.5 to 44.5
  • The Seahawks have grown from -7.5 to -11.5 against the Vikings following a dominant showing from Seattle and another flat outing from Minnesota

🏈 Bears vs. Eagles odds: Thursday Night Football on Black Friday

🏈 Broncos vs. Commanders odds: Sunday Night Football

🏈 Giants vs. Patriots odds: Monday Night Football

🔢 NFL Week 13 odds and lines

There's an advantage to betting early NFL odds when attempting to beat the closing line. The closer you wait until kickoff to make your picks, the harder it becomes to identify edges and secure the best price on most sides or totals.

❓ Who's playing on prime time in Week 13?

Week 13 opened with a Thanksgiving triple-header. Our Thursday Night Football is on Black Friday in the afternoon, as the Bears and Eagles meet. The Broncos and Commanders meet for a cross-conference battle on Sunday Night Football, while the Giants and Patriots meet to finish the week on Monday Night Football.


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