Texans vs. Chargers Predictions & Odds | Best Bet, TD Pick for NFL Week 17
Last Updated: December 27, 2025 4:30 AM EST • 3 minute read X Social Google News Link
My Texans vs. Chargers predictions take a look at a matchup that's possibly an AFC playoff preview, which kicks off on Saturday at 4:30 p.m. ET from Sofi Stadium in Inglewood, Calif. (NFL Network).
Los Angeles is as high as a 2.5-point betting favorite. But my NFL Week 17 predictions back the underdog Texans, who may be getting overlooked after almost losing to the two-win Raiders last week.
🏈 Texans vs. Chargers predictions
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| Predictions | Best odds | Confidence |
| Texans +2.5 | -115 via FanDuel | ⭐⭐⭐⭐ |
| Justin Herbert anytime touchdown scorer | +650 via DraftKings | ⭐⭐ |
💰 Texans vs. Chargers best bet
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Texans +2.5 (-115) ⭐⭐⭐⭐
Houston has won three straight games outright as underdogs. The Texans would set a franchise record with a fourth consecutively in the same season.
There's a saying that “defense travels”, and Houston’s defense may be the league’s most feared unit. The Texans rank first in total defense, second in touchdown-to-interception ratio, first in total QBR, and fourth in completion percentage allowed on deep passes.
Houston’s feared pass rush is tied for the sixth-most sacks leaguewide, and it should overwhelm the Chargers’ banged-up offensive line.
While Los Angeles is coming off a 17-point win as an underdog, teams that won as 7-point or fewer underdogs by 17-plus-points since 2010 have covered the spread just 36% of the time the following week.
Score prediction: Chargers 21, Texans 20
🙌 Best Texans vs. Chargers touchdown scorer pick
See all of our NFL touchdown props and the rest of our NFL betting analysis.
Justin Herbert, QB, Chargers: Anytime touchdown scorer (+650) ⭐⭐
Houston’s defense is allowing just 16.6 points per game, the best mark in the NFL by a full two points. But its intense pass rush should also have Justin Herbert running for his life, making him a great value play to score a touchdown on a read-option or scramble out of the pocket.
Herbert’s 308 rushing yards are the second-most among quarterbacks. Thus, this is worth a flier at +650 odds, especially with him coming off a rushing touchdown last week, and eight-plus rushing attempts for the fourth time this season.
📊 Live Texans vs. Chargers odds
📈 Texans vs. Chargers betting trends
| Texans | Statistic | Chargers |
| 10-5 | W-L record | 11-4 |
| 8-7 | ATS record | 9-6 |
| 5-9-1 | O/U record | 6-8-1 |
| 5.22 | Yards per play | 5.66 |
| 4.97 | Yards allowed per play | 5.28 |
| +15 | Turnover margin | +3 |
| 5-0 | Last 5 games | 4-1 |
| W, 23-21 vs. Raiders | Previous result | W, 34-17 vs. Cowboys |
🌤️ Texans vs. Chargers weather
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This game will be played indoors at SoFi Stadium, so weather won't be a factor for Texans vs. Chargers on Saturday.
📺 How to watch Texans vs. Chargers
- Date: Saturday, Dec. 27
- Kickoff: 4:30 p.m. ET
- Location: SoFi Stadium (Inglewood, Calif.)
- TV: NFL Network
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