Rams vs. Seahawks Expert Picks: ATS Predictions, Prop Bets & TD Picks for Thursday Night Football
Last Updated: December 18, 2025 6:17 PM EST • 5 minute read X Social Google News Link
The two Super Bowl favorites face off tonight with the Los Angeles Rams (11-3) visiting the Seattle Seahawks (11-3) in an NFC West showdown on Thursday Night Football (8:15 p.m. ET, Prime Video). Our Rams vs. Seahawks expert picks break down all of our predictions and best bets for this TNF matchup from Lumen Field in Seattle to wrap up our NFL Week 16 predictions.
🏈 Rams vs. Seahawks expert picks: TNF predictions & best bets
See all of our NFL picks and expert NFL analysis for Thursday Night Football and more.
| Best bet | Best odds | Confidence |
|---|---|---|
| Seahawks -1.5 | -110 via DraftKings | ⭐⭐⭐⭐ |
| Kenneth Walker Under 47.5 rushing yards | -110 via DraftKings | ⭐⭐⭐⭐⭐ |
| Matthew Stafford Under 232.5 passing yards | -115 via BetMGM | ⭐⭐⭐⭐⭐ |
| Sam Darnold to throw an interception | -140 via Caesars | ⭐⭐⭐⭐⭐ |
| Puka Nacua to score anytime TD | +130 via FanDuel | ⭐⭐⭐⭐⭐ |
| Kyren Williams to score first TD | +675 via Caesars | ⭐⭐⭐⭐⭐ |
🔮 Rams vs. Seahawks prediction
Seahawks -1.5 (-110) ⭐⭐⭐⭐
Gary Pearson: "(Matthew) Stafford endured his worst outing in terms of passing yards at home against the Seahawks in Week 11, finishing with just 130. While the Rams held on for a 21-19 win, it wasn't pretty. Stafford and his offense struggled in the second half, scoring one touchdown, fumbling once, and punting five times."
See Pearson's full analysis in his Rams vs. Seahawks prediction, including his favorite player prop bet and the best TNF betting trends, injury report, and more. Pearson also breaks down Stafford's chances of winning MVP heading into Thursday Night Football.
🔥 Rams vs. Seahawks player prop pick
Kenneth Walker Under 47.5 rushing yards (-110) ⭐⭐⭐⭐⭐
Dustin Saracini: "Walker hasn't sniffed this number in the last two games, and has been losing carries to the more efficient Zach Charbonnet for the last few weeks. The backfield in Seattle is almost split down the middle at this point, and with the Rams' top-10 rushing defense, I think we stay comfortably under 47.5 rushing yards."
See Saracini's full analysis in his Rams vs. Seahawks player props, including his best bet for Kyren Williams and Puka Nacua tonight on Thursday Night Football.
🐏 Matthew Stafford player prop bet
Matthew Stafford Under 232.5 passing yards (-115) ⭐⭐⭐⭐⭐
Saracini: "There's just too much going against Stafford and this passing attack for the likely MVP to go over this number. Not only did the Rams already have issues just getting to Seattle, but the weather - with wet and windy conditions - won't be conducive to passing on Thursday Night Football. With Davante Adams likely out, and with the Rams going up against one of the best passing defenses in the NFL, expect Los Angeles to keep the offense on the ground primarily. He threw for just 130 yards the last time these two met this year, too.."
See Saracini's full analysis in his Matthew Stafford player props, including his favorite bet on the Rams QB's interception total and passing attempts. I also broke down the best ways to bet on one of his emerging targets in my Konata Mumpfield player props.
🟢 Sam Darnold player prop bet
Sam Darnold to throw an interception (-140) ⭐⭐⭐⭐⭐
Saracini: "Darnold doesn't exactly have an incredible track record under the lights (we all remember the infamous 'I'm seeing ghosts' game from his time with the Jets). However, in his three prime-time games this year, he's thrown an interception in two of them, and against the Rams, he's coming off a four-interception performance. With the rain potentially playing a factor tonight, I'm expecting Los Angeles to come away with at least one turnover."
See Saracini's full analysis in his Sam Darnold player props, including two more Under plays on the Seahawks QB against his division rival. As Saracini mentioned, the rain could play a key role tonight, which I break down in our Rams vs. Seahawks weather report.
🙌 Rams vs. Seahawks anytime touchdown scorer pick
Puka Nacua to score anytime TD (+130) ⭐⭐⭐⭐⭐
Esten McLaren: "Nacua is the obvious candidate to step up in place of Adams, yet we're still getting plus-money odds for my best anytime touchdown scorer prediction. The Rams' No. 2 receiver has eight receptions on 11 red-zone targets this season, ranking second to Adams among the position group. He leads the NFL with 66 first-down receptions."
See McLaren's full analysis in his anytime touchdown scorer predictions for Thursday Night Football, including two long-shot bets on a tight end and speedy receiver. You can follow all of our NFL touchdown props for the biggest games every week.
1️⃣ Rams vs. Seahawks first touchdown scorer pick
Kyren Williams to score first TD (+675) ⭐⭐⭐⭐⭐
Corey Scott: "While taking an RB as a first touchdown scorer doesn’t offer the juiciest odds, Williams has scored four touchdowns over his last three games, making his value hard to ignore. The Rams RB scored the first touchdown for L.A. against the Detroit Lions on Sunday and also cashed as the first touchdown scorer against Seattle on Nov. 16."
See Scott's full analysis in his first touchdown scorer predictions for Thursday Night Football, including a long shot at +2200 odds to score the first touchdown. Williams also leads the most popular bets for Thursday Night Football to score first.
🚀 Rams vs. Seahawks same-game parlay
Here's a look at what our NFL expert Brenden Schaeffer is betting tonight with his best Thursday Night Football SGP paying out at +425 odds:
💵 Thursday Night Football SGP bets
- Rams ML (+105) ⭐⭐⭐⭐
- Puka Nacua Over 7.5 receptions (-124) ⭐⭐⭐⭐⭐
- Matthew Stafford Over 1.5 passing TDs (+100) ⭐⭐⭐⭐
Best SGP odds: +425 via Caesars ($10 to win $42.50)
See Schaeffer's full analysis in his Rams vs. Seahawks same-game parlay, including his analysis for all three SGP bets for Thursday Night Football. You can follow all of our NFL same-game parlay bets for the biggest games every week.
📊 Rams vs. Seahawks odds: TNF
See the latest NFL odds for every game in real time.
📺 How to watch Thursday Night Football: Rams vs. Seahawks
- Date: Thursday, Dec. 18
- Kickoff: 8:15 p.m. ET
- Location: Lumen Field (Seattle)
- TV: Prime Video
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