NFL Predictions Week 2: Best Bets & Odds for Monday Night Football

We have two games left in the NFL Week 2 slate with a Monday Night Football doubleheader tonight.
NFL Predictions Week 2: Best Bets & Odds for Monday Night Football
Pictured: Los Angeles Chargers quarterback Justin Herbert (10) and center Bradley Bozeman (75) celebrate after the game against the Kansas City Chiefs. Photo by Amanda Perobelli / Reuters via Imagn Images.

Our NFL predictions for Week 2 round up all of today's best NFL picks from our betting experts, including the Monday Night Football doubleheader tonight featuring Buccaneers vs. Texans and Chargers vs. Raiders.


🏈 NFL predictions for Week 2

Track the latest NFL scores for line movement and matchup info.


💰 NFL odds & expert picks: Week 2

Live odds from our best NFL betting sites; updated in real time. 

📊 Buccaneers vs. Texans odds

  • Date: Monday, Sept. 15
  • Kickoff: 7 p.m. ET
  • Location: NRG Stadium (Houston, Texas)
  • How to watch: ABC/ESPN

🔮 Buccaneers vs. Texans prediction

Here's why NFL betting expert Gary Pearson is betting on Houston in his Buccaneers vs. Texans prediction.

"Inept, listless, inefficient, ghastly. Pick your favorite of those four words, and you have a perfect embodiment of the Texans' Week 1 offensive performance. There is some good news, though. First, they get to play at home, which makes snap counts easier at the very least.

And second, the Buccaneers' pass defense struggled against Atlanta Falcons QB Michael Penix Jr. in the opener, allowing 298 yards while receiving the same 21st-ranked pressure grade (61.9) it did last season. That should present an ideal opportunity - even with center Jake Andrews unavailable - for Stroud and his receivers to gain confidence and source some productivity."


📊 Chargers vs. Raiders odds

  • Date: Monday, Sept. 15
  • Kickoff: 10 p.m. ET
  • Location: Allegiant Stadium (Las Vegas, Nev.)
  • How to watch: ESPN

🔮 Chargers vs. Raiders prediction

Here's why Pearson is betting on Los Angeles in his Chargers vs. Raiders prediction:

"The Chargers were arguably the most impressive team in Week 1, with almost all facets ticking efficiently. The offense takes most of the plaudits, though, with Justin Herbert - the fifth-most clutch QB - starting his season how we would have envisioned in his best-case scenario dream. 

He will face a Las Vegas Raiders defense that was made to look much better than it is by the New England Patriots, not unlike the Washington Commanders when they played the New York Giants."

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