NFL Predictions Week 13: Best Bets & Odds for Every Game This Week

One of the best weeks of football season is here as we offer our NFL predictions for Week 13, including live odds and best bets for every game from Thanksgiving and Black Friday through the Sunday and Monday action.

Bookmark this page and check back often as we'll be updating it throughout the week with our best ATS picks, player prop bets, O/U predictions, and more for every single game this week.

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🏈 NFL predictions for Week 13

See all of our NFL picks for every Week 13 game with the latest odds.

• Early Packers vs. Lions prediction
• Packers vs. Lions prediction (coming soon)
• Packers vs. Lions player props (coming soon)
• Packers vs. Lions same-game parlay (coming soon)
• Packers vs. Lions anytime touchdown scorer predictions (coming soon)
• Packers vs. Lions AI predictions (coming soon)
• Packers vs. Lions best bets (coming soon)
• Early Chiefs vs. Cowboys prediction (coming soon)
• Chiefs vs. Cowboys prediction (coming soon)
• Chiefs vs. Cowboys player props (coming soon)
• Chiefs vs. Cowboys same-game parlay (coming soon)
• Chiefs vs. Cowboys anytime touchdown scorer predictions (coming soon)
• Travis Kelce player props (coming soon)
• Chiefs vs. Cowboys AI predictions (coming soon)
• Chiefs vs. Cowboys best bets (coming soon)
• Early Bengals vs. Ravens prediction (coming soon)
• Bengals vs. Ravens prediction (coming soon)
• Bengals vs. Ravens player props (coming soon)
• Bengals vs. Ravens same-game parlay (coming soon)
• Bengals vs. Ravens anytime touchdown scorer predictions (coming soon)
• Bengals vs. Ravens weather report (coming soon)
• Bengals vs. Ravens AI predictions (coming soon)
• Bengals vs. Ravens best bets (coming soon)
• Early Bears vs. Eagles prediction (coming soon)
• Bears vs. Eagles prediction (coming soon)
• Bears vs. Eagles player props (coming soon)
• Bears vs. Eagles same-game parlay (coming soon)
• Bears vs. Eagles anytime touchdown scorer predictions (coming soon)
• Bears vs. Eagles first touchdown scorer predictions (coming soon)
• Bears vs. Eagles weather report (coming soon)
• Bears vs. Eagles AI predictions (coming soon)
• Bears vs. Eagles best bets (coming soon)
• 49ers vs. Browns player props (coming soon)
• Jaguars vs. Titans player props (coming soon)
• Texans vs. Colts player props (coming soon)
• Saints vs. Dolphins player props (coming soon)
• Falcons vs. Jets player props (coming soon)
• Cardinals vs. Buccaneers player props (coming soon)
• Rams vs. Panthers player props (coming soon)
• Vikings vs. Seahawks player props (coming soon)
• Bills vs. Chargers player props (coming soon)
• Raiders vs. Chargers player props (coming soon)
• Early Broncos vs. Commanders prediction (coming soon)
• Broncos vs. Commanders prediction (coming soon)
• Broncos vs. Commanders player props (coming soon)
• Broncos vs. Commanders same-game parlay (coming soon)
• Broncos vs. Commanders anytime touchdown scorer predictions (coming soon)
• Broncos vs. Commanders first touchdown scorer predictions (coming soon)
• Bo Nix player props (coming soon)
• Broncos vs. Commanders weather report (coming soon)
• Broncos vs. Commanders AI predictions (coming soon)
• Broncos vs. Commanders best bets (coming soon)
• Early Giants vs. Patriots prediction (coming soon)
• Giants vs. Patriots prediction (coming soon)
• Giants vs. Patriots player props (coming soon)
• Giants vs. Patriots same-game parlay (coming soon)
• Giants vs. Patriots anytime touchdown scorer predictions (coming soon)
• Giants vs. Patriots first touchdown scorer predictions (coming soon)
• Giants vs. Patriots weather report (coming soon)
• Giants vs. Patriots AI predictions (coming soon)
• Giants vs. Patriots best bets (coming soon)

💰 NFL odds & expert picks: Week 13

Live NFL odds for every Week 13 game from our best NFL betting sites.

📊 Packers vs. Lions odds

• Date: Thursday, Nov. 27
• Kickoff: 1 p.m. ET
• Location: Ford Field (Detroit)
• TV: FOX

🔮 Early Packers vs. Lions prediction

🦁 Lions -3 (-104)

Neither of these teams are at full strength entering this huge divisional matchup. On a short week, I trust Dan Campbell and Kelvin Sheppard more to punch back after a Week 1 loss in Green Bay.

📊 Chiefs vs. Cowboys odds

• Date: Thursday, Nov. 27
• Kickoff: 4:30 p.m. ET
• Location: AT&T Stadium (Arlington, Texas)
• TV: CBS

🔮 Early Chiefs vs. Cowboys prediction

🤠 Cowboys +3.5 (-110)

It's easy to write off the Cowboys after the offseason drama and 3-5-1 start, but they've won two straight after trading for star defensive tackle Quinnen Williams. After a potentially season-defining win over Philly, expect Dallas to show up at home on a short week.

📊 Bengals vs. Ravens odds

• Date: Thursday, Nov. 27
• Kickoff: 8:20 p.m. ET
• Location: M&T Bank Stadium (Baltimore)
• TV: NBC

🔮 Early Bengals vs. Ravens prediction

🐦‍⬛ Ravens -7 (-113)

Baltimore simply hasn't looked right even amid a five-game win streak because of a lethargic offense that can't get ahead of the chains. Cue the Bengals defense, which is historically one of the worst of all time. The Ravens should look closer to their old form in a must-win over a spiraling rival.

📊 Bears vs. Eagles odds

• Date: Friday, Nov. 28
• Kickoff: 3 p.m. ET
• Location: Lincoln Financial Field (Philadelphia)
• TV: Prime Video

🔮 Early Bears vs. Eagles prediction

🐻 Bears +7 (-114)

At some point, it's OK to acknowledge the Bears might actually be good - at least offensively, which has been the driving force for a four-game win streak. The Eagles aren't in sync right now, so this feels like too much to lay on a short week.

📊 Jaguars vs. Titans odds

• Date: Sunday, Nov. 30
• Kickoff: 1 p.m. ET
• Location: Nissan Stadium (Nashville, Tenn.)
• TV: CBS

🔮 Early Jaguars vs. Titans prediction

⚔️ Titans +7 (-115)

The Titans have something real in rookie QB Cam Ward, whose play has helped Tennessee stay within one score in three straight losses. I expect the same against a surging yet familiar and inconsistent Jacksonville side that barely beat Arizona last week.

📊 Falcons vs. Jets odds

• Date: Sunday, Nov. 30
• Kickoff: 1 p.m. ET
• Location: MetLife Stadium (East Rutherford, N.J.)
• TV: FOX

🔮 Early Falcons vs. Jets prediction

🪶 Falcons -2.5 (-108)

The Falcons' season is teetering on irrelevancy - if it's not there already - but it's still talented enough to beat the lower class of the NFL. That would include the Jets, who have lost two straight by 13 points after a midseason fire sale.

📊 Rams vs. Panthers odds

• Date: Sunday, Nov. 30
• Kickoff: 1 p.m. ET
• Location: Bank of America Stadium (Charlotte, N.C.)
• TV: FOX

🔮 Early Rams vs. Panthers prediction

🐾 Panthers +10 (-115)

The Rams are a wagon right now, so you'll have to pinch your nose to bet against them in any matchup - especially against a non-title contender. Still, double digits is a lot for a Carolina side that has won five of seven games entering Monday night.

📊 Saints vs. Dolphins odds

• Date: Sunday, Nov. 30
• Kickoff: 1 p.m. ET
• Location: Hard Rock Stadium (Miami Gardens, Fla.)
• TV: FOX

🔮 Early Saints vs. Dolphins prediction

🐬 Dolphins -5.5 (-110)

Is this a trap? Or is Miami good again? Two straight wins over the Bills and Commanders are one thing, but the bye week tips it over the edge for this matchup with the Saints, who are distinctly not good after a 2-9 start with six double-digit losses.

📊 Cardinals vs. Buccaneers odds

• Date: Sunday, Nov. 30
• Kickoff: 1 p.m. ET
• Location: Raymond James Stadium (Tampa, Fla.)
• TV: FOX

🔮 Early Cardinals vs. Buccaneers prediction

🌵 Cardinals +3 (-110)

Will Baker Mayfield be fully healthy for this matchup after leaving Sunday's loss to the Rams? Even if he plays, I still like Arizona's defensive front to make life miserable for Mayfield and his thinned supporting cast in a potential upset spot.

📊 49ers vs. Browns odds

• Date: Sunday, Nov. 30
• Kickoff: 1 p.m. ET
• Location: Huntington Bank Field (Cleveland)
• TV: CBS

🔮 Early 49ers vs. Browns prediction

⛏️ 49ers -6.5 (-109)

Congratulations to Shedeur Sanders for his first win over a Raiders team that fired its offensive coordinator that night. Life will be tougher against a competent 49ers team that is finally starting to resemble a playoff team with some of its key pieces back in the fold.

📊 Texans vs. Colts odds

• Date: Sunday, Nov. 30
• Kickoff: 1 p.m. ET
• Location: Lucas Oil Stadium (Indianapolis)
• TV: CBS

🔮 Early Texans vs. Colts prediction

🐂 Texans +3.5 (-106)

Indianapolis was probably never as good as its 7-1 start, and it isn't as bad as its 1-2 record since. But the Texans' defense should cause nightmares for Daniel Jones and Co., and if they can bottle up Jonathan Taylor, their offense has been efficient enough with Davis Mills to keep it close or even win outright.

📊 Vikings vs. Seahawks odds

• Date: Sunday, Nov. 30
• Kickoff: 4:05 p.m. ET
• Location: Lumen Field (Seattle)
• TV: FOX

🔮 Early Vikings vs. Seahawks prediction

🟢 Seahawks -8.5 (-115)

J.J. McCarthy has been the worst starting quarterback in the NFL and one of the worst in league history by advanced metrics. The Seahawks' defense, on the other hand, is historically great. That mismatch alone has me expecting a home blowout win in a bounce-back spot for Seattle.

📊 Bills vs. Steelers odds

• Date: Sunday, Nov. 30
• Kickoff: 4:25 p.m. ET
• Location: Acrisure Stadium (Pittsburgh)
• TV: CBS

🔮 Early Bills vs. Steelers prediction

🦬 Bills -3.5 (-115)

The Bills' run defense has been gashed in recent weeks and cost the team accordingly. Pittsburgh simply isn't built to attack that weakness in the same way, and Buffalo is well equipped to attack the Steelers' weaknesses downfield.

📊 Raiders vs. Chargers odds

• Date: Sunday, Nov. 30
• Kickoff: 4:25 p.m. ET
• Location: SoFi Stadium (Inglewood, Calif.)
• TV: CBS

🔮 Early Raiders vs. Chargers prediction

⚡️ Chargers -9.5 (-110)

It's tough to lay close to 10 points on a Chargers team that just got taken to the cleaners, but a week off and a matchup with a Raiders team in disarray should help Justin Herbert and Co. bounce back and stay on pace in the AFC playoff race.

📊 Broncos vs. Commanders odds

• Date: Sunday, Nov. 30
• Kickoff: 8:20 p.m. ET
• Location: Northwest Stadium (Landover, Md.)
• TV: NBC

🔮 Early Broncos vs. Commanders prediction

🐎 Broncos -6.5 (-110)

The Broncos have won three straight games by exactly three points, but two of them came against likely playoff teams and none came after a week off. The Commanders are rested, too, but six straight losses don't wear off in a week.

📊 Giants vs. Patriots odds

• Date: Monday, Dec. 1
• Kickoff: 8:15 p.m. ET
• Location: Gillette Stadium (Foxborough, Mass.)
• TV: ESPN

🔮 Early Giants vs. Patriots prediction

🪖 Patriots -7.5 (-102)

The Jameis Winston era is off to a riveting start for the Giants, but New York is still a deeply flawed team that should be taken advantage of by MVP candidate Drake Maye and the current AFC leaders.

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💡 NFL expert picks for Week 13

Follow all of our NFL analysis for Week 13 throughout the week.

• NFL Thanksgiving predictions (coming soon)
• NFL picks against the spread Week 13 (coming soon)
• NFL survivor picks Week 13 (coming soon)
• NFL AI predictions Week 13 (coming soon)
• NFL weather report Week 13 (coming soon)
• NFL upset picks Week 13 (coming soon)
• NFL player props for Thanksgiving (coming soon)
• NFL anytime touchdown scorers for Thanksgiving (coming soon)
• NFL first touchdown scorers for Thanksgiving (coming soon)
• NFL best bets Week 13 (coming soon)
• NFL anytime touchdown scorer predictions Week 13 (coming soon)
• NFL first touchdown scorer predictions Week 13 (coming soon)
• NFL 2+ touchdown scorer predictions Week 13 (coming soon)
• NFL anytime touchdown scorer parlay Week 13 (coming soon)

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