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Luke Musgrave of the Green Bay Packers reacts after scoring a touchdown in the fourth quarter of a game against the Los Angeles Rams as we look at our Packers-49ers prediction.
Luke Musgrave of the Green Bay Packers reacts after scoring a touchdown in the fourth quarter of a game against the Los Angeles Rams. Photo by Patrick McDermott/Getty Images/AFP.

The San Francisco 49ers start their postseason against a Green Bay Packers team fresh off a colossal upset during Wild Card Weekend, and we're offering our top Packers vs. 49ers prediction based on the best NFL odds.

The Green Bay Packers pulled off a surprising victory against the NFC East champion Dallas Cowboys, stunning both the team and the football world. They established a dominant 27-0 lead at one point during Wild Card Weekend.

Their "reward" is a trip to San Francisco to face the top-seeded 49ers, who are well-rested following their bye week and serve as the Super Bowl odds favorites, as we discuss further in our Super Bowl predictions

Will San Francisco dominate the Packers? Or will Kyle Shanahan suffer another disappointing playoff exit? The weather could be a factor, with a 60% chance of precipitation forecasted for kickoff.

Our Mike Spector looks at what we should expect from the 49ers signal-caller in his Brock Purdy NFL player props, while Philip Woods examines the backfield with his Christian McCaffrey NFL player props.

As part of our NFL Divisional Round predictions and in conjunction with our Jordan Love NFL player props, here are our best Packers vs. 49ers predictions and our NFL picks (odds via our best NFL betting sites; pick confidence is based on a 1-to-5-star scale).

Packers vs. 49ers prediction

Luke Musgrave Over 17.5 receiving yards (-114 via FanDuel) ⭐⭐⭐

We offered the 49ers -6.5 first-half spread on Monday, but we're going back to what feels right with a player prop as our second pick.

Packers tight end Luke Musgrave enjoyed a big game against the Cowboys during Wild Card Weekend, hauling in three catches for 52 receiving yards.

The tight end was building momentum during the regular season before a lacerated kidney sidelined him for almost all of the second half. However, after returning in Week 18, he looked truly back to normal during the Packers' wild-card win in Dallas. The data suggests he'll continue to be featured in Green Bay's passing attack.

Musgrave's average receiving yards projection is 26.58 across five projection models. When we run that projection against FanDuel's -114 odds on Over 17.5 receiving yards, we're getting roughly 13% positive expected value on this bet.

Not only are we receiving great value relative to the projection, but FanDuel is also offering a rogue line with its 17.5 receiving yards total. All of our other best sports betting apps are up to 19.5 receiving yards for Musgrave, with most juicing the Over more than FanDuel is this lower line.

The talented pass-catcher could clear this total with just two grabs, making this a very enticing bet.

FanDuel is offering a boost of -135 to +120 for the Packers to cover +14.5 and Jordan Love to finish with 200-plus passing yards.

49ers -6.5 first half (-105 via bet365) ⭐⭐

Pick made Monday at 10:30 a.m. ET.

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Packers vs. 49ers best odds

FanDuel (-114)

DraftKingsFanDuelBetMGMCaesarsbet365
19.517.519.519.519.5
-110-114-118-120-110

FanDuel is the only one of our best sports betting sites offering this line that's two yards lower than the consensus. Therefore, we'll take advantage of its blunder and hit the Over there.

This truly shows the value of maintaining access to multiple sportsbooks, especially when betting on player props. The wager goes from a bet that you'd be wise to leave alone at any of our other best sportsbooks to a smash spot at FanDuel.

For the best price on this bet, be sure to use our exclusive FanDuel promo code!

Packers vs. 49ers odds

Packers vs. 49ers odds analysis

The 49ers opened as 9.5-point favorites, and that line is still sitting there on Thursday at all of our best live betting sites.

For those looking to bet on the underdogs, nearly all of our sites with the best sportsbook promos are offering standard -110 odds on Packers +9.5, with DraftKings' -108 proving to be the best value on that side of the spread.

The total ranges from 50 to 50.5, making it the highest total of any game during the divisional round.

Packers vs. 49ers game info

  • When: Saturday, Jan. 20 at 8:15 p.m. ET
  • Where: Levi's Stadium, Santa Clara, CA
  • How to watch: Fox
  • Weather: 58 degrees, %60 chance of precipitation, 7-mph winds

Packers vs. 49ers prediction made Thursday at 3:30 p.m. ET.

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