Los Angeles Rams 2025 Schedule, Odds & Predictions: Updates Ahead of Week 1
We're breaking down the Los Angeles Rams schedule, odds, and predictions for the 2025 NFL season following the official schedule release. The Rams are projected to win 9.5 games across our best sports betting sites, and we're offering our 2025 win-loss predictions with AI picks for all 17 games.
📅 Los Angeles Rams 2025 schedule & odds for every game
Odds via DraftKings as of Saturday, Aug. 23. All times listed in Eastern Time.
| Week | Date | Opponent | Favorite |
|---|---|---|---|
| 1 | Sunday, Sept. 7 @ 4:25 PM | vs. Texans | Rams -2.5 |
| 2 | Sunday, Sept. 14 @ 1 PM | at Titans | Rams -5.5 |
| 3 | Sunday, Sept. 21 @ 1 PM | at Eagles | Eagles -4.5 |
| 4 | Sunday, Sept. 28 @ 4:05 PM | vs. Colts | Rams -6.5 |
| 5 | Thursday, Oct. 2 @ 8:15 PM | vs. 49ers | Rams -1.5 |
| 6 | Sunday, Oct. 12 @ 1 PM | at Ravens | Ravens -5.5 |
| 7 | Sunday, Oct. 19 @ 9:30 AM | vs. Jaguars | Rams -3.5 |
| 8 | BYE WEEK | - | - |
| 9 | Sunday, Nov. 2 @ 4:05 PM | vs. Saints | Rams -9.5 |
| 10 | Sunday, Nov. 9 @ 4:25 PM | at 49ers | 49ers -1.5 |
| 11 | Sunday, Nov. 16 @ 4:05 PM | vs. Seahawks | Rams -4.5 |
| 12 | Sunday, Nov. 23 @ 8:20 PM | vs. Buccaneers | Rams -2.5 |
| 13 | Sunday, Nov. 30 @ 1 PM | at Panthers | Rams -3.5 |
| 14 | Sunday, Dec. 7 @ 4:25 PM | at Cardinals | Rams -1.5 |
| 15 | Sunday, Dec. 14 @ 4:25 PM | vs. Lions | Lions -1.5 |
| 16 | Thursday, Dec. 18 @ 8:15 PM | at Seahawks | Rams -1.5 |
| 17 | Monday, Dec. 29 @ 8:15 PM | at Falcons | Rams -3 |
| 18 | Sunday, Jan. 4 @ TBD | vs. Cardinals | Rams -4.5 |
👉 Check out the full 2025 NFL schedule with odds for every game.
📊 Los Angeles Rams odds to win Super Bowl & best futures bets
🔎 Our NFL player prop odds tool can help you find the best NFL odds across legal sportsbooks in your area!
🐏 Los Angeles Rams 2025 season update
- There's little question for the Rams to be successful this season, 37-year-old quarterback Matthew Stafford will need to be healthy. That certainly is in question as the preseason ended. According to NFL.com, he said, "Everything under the sun feels like" he will be ready for the Week 1 opener against the Houston Texans, but there has been no confirmation.
- The Rams second- and third-string defense sacked Cleveland Browns quarterback five times in their final preseason game Aug. 23.
- Tackle Alaric Jackson is hoping to be ready for the season opener, but he has been dealing with blood clots and does not have an official timeline to return.
💰 Los Angeles Rams O/U win total
Latest NFL win totals via BetMGM as of Saturday, Aug. 23.
- Over 9.5 wins: -145 (bet $10 to win $6.06)
- Under 9.5 wins: +120 (bet $10 to win $12.00)
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🔮 Los Angeles Rams 2025 predictions: Game-by-game picks & final record
Check out our 2025 NFL season predictions for projected standings, playoff results, and award winners - and a breakdown of how our AI model predicts every game.
🤖 Los Angeles Rams 2025 AI projections
- Week 1: Rams 27, Texans 24 ✅
- Week 2: Rams 24, Titans 23 ✅
- Week 3: Eagles 27, Rams 23 ❌
- Week 4: Rams 23, Colts 20 ✅
- Week 5: 49ers 30, Rams 23 ❌
- Week 6: Ravens 30, Rams 20 ❌
- Week 7: Jaguars 30, Rams 24 ❌
- Week 9: Rams 29, Saints 23 ✅
- Week 10: Rams 34, 49ers 31 ✅
- Week 11: Seahawks 27, Rams 24 ❌
- Week 12: Rams 30, Buccaneers 23 ✅
- Week 13: Rams 27, Panthers 23 ✅
- Week 14: Rams 30, Cardinals 23 ✅
- Week 15: Rams 27, Lions 26 ✅
- Week 16: Seahawks 27, Rams 23 ❌
- Week 17: Rams 27, Falcons 23 ✅
- Week 18: Rams 26, Cardinals 23 ✅
🏈 Los Angeles Rams 2025 record prediction
- Projected win-loss record: 11-6
🐏 Los Angeles Rams Week 1 odds vs. Texans
The Rams host the Houston Texas at SoFi Stadium on Sunday, Sept. 7. Kickoff is set for 4:25 p.m. ET. Los Angeles opened as a 3.5-point favorite. That line had dropped to Rams -2.5 as of Aug. 23.
🔮 2025 NFL season previews & predictions
Following the NFL schedule release, we broke down the odds for every game and asked AI to predict every game (and more). Below are our team-by-team schedules, odds, and predictions for Week 1 through Week 18.
- NFL Week 1 odds and schedule
- NFL Week 1 picks against the spread
- NFL International schedule and odds
- NFL Thanksgiving schedule and odds
- NFL Christmas schedule and odds
- NFL Week 18 odds and schedule
- Best revenge games for the 2025-26 season
💵 Best NFL betting sites
Ready to bet on the NFL this season? Check out our best NFL betting sites and the best sportsbook promos for the 2025-26 NFL season:
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