Eagles vs. Commanders Predictions & Odds: NFL Week 16 Betting Preview
Philadelphia travels to Washington for Saturday Night Football, and I'm dropping my best Eagles vs. Commanders predictions to get you set for the 5 p.m. ET kickoff at Northwest Stadium (FOX).
Jalen Hurts and Co. come into this one as 6.5-point favorites, and I think they should be laying more points. Will they blow out an opponent for the second straight week? It's likely. Let's get into it.
🏈 Eagles vs. Commanders prediction
Don't miss the rest of our NFL picks for every game this season.
Eagles -6.5 (-120) ⭐⭐⭐⭐⭐
If I was an Eagles fan, I'd be offended. Yes, we know about the offensive struggles in Philly, but not being favored by more than a touchdown against a team that's 4-10 might be a gut punch. You'll say "this game is a trap," and I'll say, Philadelphia is back. This is another tune-up contest the Eagles have to have to lock up the division. Marcus Mariota vs. the Philly front-seven is the matchup to watch, and I choose the latter every time. Eagles by eight.
Score prediction: Eagles 28, Commanders 20
💡 More Week 16 predictions
Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game in Week 16.
🙌 Best Eagles vs. Commanders TD pick
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A.J. Brown, WR, Eagles: TD Pick (+125) ⭐⭐⭐⭐⭐
Don't look now, but complaining about the offense might have worked - at least for Brown. He's caught three touchdowns over the last three weeks, and continues to get fed in the red zone. He's got 27 targets over that span, too - I think Hurts finally realized what kind of weapon Brown really is this season. I'm targeting him to score at least once against a bad secondary.
📊 Live Eagles vs. Commanders odds
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📈 Eagles vs. Commanders betting trends
| Eagles | Statistic | Commanders |
|---|---|---|
| 9-5 | W-L record | 4-10 |
| 8-6 | ATS record | 5-9 |
| 5-9 | O/U record | 7-6-1 |
| 5.3 | Yards per play | 5.5 |
| 5.1 | Yards allowed per play | 6.1 |
| +0.3 | Turnover margin | -0.9 |
| 2-3 | Last 5 games | 1-4 |
| W, 55-23 | Previous result | L, 55-23 |
🚑 Eagles vs. Commanders injury report
🌤️ Eagles vs. Commanders weather
It's projected to be a chilly Saturday as the Eagles look to put together back-to-back strong performances, while the Commanders play out the string. It'll be close to 35 degrees Fahrenheit and partly cloudy come kickoff time.
Liam Fox has you dialed in for the NFL weather report for Week 16.
📺 How to watch Eagles vs. Commanders
- Date: Saturday, Dec. 20, 2025
- Kickoff: 5 p.m. ET
- Location: Northwest Stadium (Washington)
- TV: FOX
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