Eagles vs. Commanders Predictions & Odds Today: NFL Week 16 Betting Preview
My best Eagles vs. Commanders predictions today is backing the class of the NFC East in Saturday's matchup from Northwest Stadium in Landover, Md.
Philadelphia is a 6.5-point road betting favorite ahead of kickoff at 5 p.m. ET (FOX). I'm also targeting a player prop for an Eagles wideout that has quietly turned his season around as of late.
🏈 Eagles vs. Commanders prediction
Don't miss the rest of our NFL picks for every game this season.
Eagles -6.5 (-120) ⭐⭐⭐⭐⭐
If I was an Eagles fan, I'd be offended. Yes, we know about the offensive struggles in Philly, but not being favored by more than a touchdown against a team that's 4-10 might be a gut punch. You'll say "this game is a trap," and I'll say, Philadelphia is back. This is another tune-up contest the Eagles have to have to lock up the division. Marcus Mariota vs. the Philly front-seven is the matchup to watch, and I choose the latter every time. Eagles by eight.
The most confident play from our Eagles vs. Commanders anytime touchdown scorer predictions should help this spread along.
Score prediction: Eagles 28, Commanders 20
💡 More Week 16 predictions
Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game in Week 16.
🙌 Best Eagles vs. Commanders TD pick
Search the best NFL player prop odds for any team or player across every market from legal sportsbooks in your area.
A.J. Brown, WR, Eagles: TD Pick (+125) ⭐⭐⭐⭐⭐
Don't look now, but complaining about the offense may have worked - at least for Brown. He's hauled in three touchdowns over the last three weeks and continues to get fed in the red zone. He's got 27 targets over that span, too - I think Hurts finally realized what kind of weapon Brown really is this season. I'm targeting him to score at least once against a bad secondary.
Want another TD scorer? Our Corey Scott has someone in mind in his Eagles vs. Commanders player props.
📊 Live Eagles vs. Commanders odds
See the latest NFL odds for every game in real time.
📈 Eagles vs. Commanders betting trends
| Eagles | Statistic | Commanders |
|---|---|---|
| 9-5 | W-L record | 4-10 |
| 8-6 | ATS record | 5-9 |
| 5-9 | O/U record | 7-6-1 |
| 5.3 | Yards per play | 5.5 |
| 5.1 | Yards allowed per play | 6.1 |
| +0.3 | Turnover margin | -0.9 |
| 2-3 | Last 5 games | 1-4 |
| W, 55-23 | Previous result | L, 55-23 |
🚑 Eagles vs. Commanders injury report
🌤️ Eagles vs. Commanders weather
It's projected to be a chilly Saturday as the Eagles look to put together back-to-back strong performances, while the Commanders play out the string. It'll be close to 35 degrees Fahrenheit and partly cloudy come kickoff time.
Liam Fox has you dialed in for the NFL weather report for Week 16.
📺 How to watch Eagles vs. Commanders
- Date: Saturday, Dec. 20, 2025
- Kickoff: 5 p.m. ET
- Location: Northwest Stadium (Washington)
- TV: FOX
💡 NFL expert picks for Week 16
- NFL picks against the spread Week 16
- NFL survivor picks Week 16
- NFL AI predictions Week 16
- NFL weather report Week 16
- NFL upset picks Week 16
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