Chargers vs. Raiders Prediction, Monday Night Football Odds & MNF Picks
The Los Angeles Chargers travel to Allegiant Stadium in Sin City to take on the Las Vegas Raiders in the second game of the Monday Night Football double-header, and my Chargers vs. Raiders prediction expects another win and cover from Jim Harbaugh's team.
The Chargers are the 3 or 3.5-point betting favorite, and the NFL picks below also feature one of the best young receivers around. The game will start at 10 p.m. ET (ESPN). In the lead-up to kickoff, check out the rest of the NFL predictions for Week 2.
🏈 Chargers vs. Raiders prediction for Monday Night Football
NFL expert picks based on the latest Monday Night Football odds; subject to change.
- Moneyline pick: Chargers (-174 via FanDuel) ⭐⭐⭐
- Against the spread pick: Chargers -3 (-120 via FanDuel) ⭐⭐⭐⭐⭐
- Over/Under pick: Under 46.5 (-108 via DraftKings) ⭐⭐⭐
📝 Monday Night Football preview & best bet
Track the latest NFL scores for line movement and matchup info.
⚡️ Chargers -3 (-120) ⭐⭐⭐⭐
The Chargers were arguably the most impressive team in Week 1, with almost all facets ticking efficiently. The offense takes most of the plaudits, though, with Justin Herbert - the fifth-most clutch QB - starting his season how we would have envisioned in his best-case scenario dream.
He will face a Las Vegas Raiders defense that was made to look much better than it is by the New England Patriots, not unlike the Washington Commanders when they played the New York Giants.
Although defensive coordinator Patrick Graham's unit only allowed 13 points, they allowed 287 passing yards, with Drake Maye completing 12 passes of at least 10 yards.
Herbert, meanwhile, had his way against a Kansas City Chiefs pass defense that was among the better units last season (fifth in coverage, eighth-best pressure unit). The Chargers aired it out much more than most thought they would. Herbert has also been lights out against the Raiders, tossing 21 touchdowns and just two picks in nine games.
I expect them to return to their bread-and-butter ground-and-pound game, which should even more effectively open up the aerial bombardment.
With the addition of rookie running back Omarion Hampton and wide receiver Keenan Allen, along with Herbert's ability to scramble and make plays with his feet, their dynamic and versatile attack will be too much for the Raiders to cope with.
FanDuel is the only one of the best sports betting apps that still offers the -3 spread. While you'll have to take a cut in the profits on a winning $10 bet ($8.33 as opposed to $10 at Caesars), at least you'll receive your stake back if Los Angeles wins by only three.
💰 Best Chargers vs. Raiders player prop bet for Monday Night Football
Our NFL player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
⬆️ Ladd McConkey Over 72.5 receiving yards (-110) ⭐⭐⭐⭐
With more chemistry than Travis Kelce and Taylor Swift, Herbert and Ladd McConkey's on-field relationship gets stronger each game.
The second-year receiver has at least 74 receiving yards in eight of the past nine games. That 74-yard output occurred in Week 1 against a Chiefs coverage unit that was ranked fifth last season (PFF).
McConkey had 95 yards on five receptions in Week 18 at Allegiant Stadium. bet365 offers the lowest total (72.5 yards) at -110 odds, with most of the other best sports betting apps offering less value (-115 at FanDuel and BetMGM).
📊 Chargers vs. Raiders odds: MNF
NFL odds update live in real time.
📈 Chargers vs. Raiders opening odds
- Moneyline: Chargers -180 | Raiders +150
- Spread: Chargers -3.5 (+100) | Raiders +3.5 (-125)
- Over/Under: Over 45.5 (-105) | Under 45.5 (-115)
🔍 Chargers vs. Raiders odds analysis
The Chargers are the 3 or 3.5-point betting favorite, which has remained stable throughout the week leading up to kickoff. The majority of the betting public is backing the visitors, with 63% of the bets on the Chargers. The total sits at 46.5, increasing from 45.5, with 51% backing the Under.
🔢 Chargers vs. Raiders stats
Season stats courtesy of Pro Football Reference.
| Chargers (1-0) | Statistic (per game) | Raiders (1-0) |
|---|---|---|
| 27 | Points | 20 |
| 21 | Points allowed | 13 |
| 0 | Turnover margin | 0 |
| 304 | Passing yards | 333 |
| 90 | Rushing yards | 56 |
| 249 | Passing yards allowed | 276 |
| 98 | Rushing yards allowed | 60 |
| 0.4 | Net yards per play | 1.4 |
🚑 Chargers vs. Raiders injury report
📺 How to watch Monday Night Football
- When: Monday, Sept. 15
- Kickoff: 10 p.m. ET
- Where: Allegiant Stadium (Las Vegas)
- How to watch: ESPN
❓ Monday Night Football FAQs
Who plays on Monday Night Football?
Monday Night Football features the Los Angeles Chargers and Las Vegas Raiders.
When is Monday Night Football?
The second half of the Monday Night Football double-header starts at 10 p.m. ET from Allegiant Stadium in Las Vegas.
Who is favored to win Monday Night Football?
The Chargers are the 3.5-point betting favorite for MNF.
How do NFL odds work?
When betting on NFL odds, the point spread shows how many points the favorite needs to win by in order to cash the bet. For example, a favorite of -3 must win by more than 3 points to cover the spread, while an underdog at +3 must win outright or lose by fewer than 3 points to cover the spread.
Moneyline odds represent the payout for picking the outright winner (+200 means a $100 bet wins $200, while -200 means a $200 bet wins $100). Over/Unders let you wager on whether the combined total will be higher or lower than the set number.
You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.
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