Buccaneers vs. 49ers Odds, Picks, Predictions Week 14: Defenses to Rule the Day
Tom Brady returns home as the Tampa Bay Buccaneers face the San Francisco 49ers on the West Coast. It was a narrow 17-16 victory for the Buccaneers last week over the New Orleans Saints at home. Is the veteran quarterback capable of keeping the Buccaneers' winning hopes alive? Read on for our top Buccaneers-49ers picks.
The age gap between Buccaneers quarterback Brady (45) and San Francisco 49ers rookie Brock Purdy (22) has dominated headlines this week. But don't let the intriguing QB matchup distract you from two of the NFL's best defenses taking the field Sunday.
The 49ers (8-4) own the league's No. 1 overall defense and scoring defense and have limited teams to 11.6 points per game during their five-game winning streak.
The Bucs (6-6) went from averaging 30.1 PPG in 2021 to 18.1 points this year. As a result, the team also relies heavily on a D that holds teams to 18.3 PPG.
Will points be at a premium when these two playoff hopefuls meet in Week 14?
Here are our best Buccaneers vs. 49ers Week 14 NFL picks (odds via PointsBet; pick confidence based on a 1-to-5-star scale).
Check out our NFL best bets.
Buccaneers vs. 49ers Game Info
- Date: Sunday, Dec. 11, 4:25 p.m. ET
- TV: FOX
- Location: Levi's Stadium, Santa Clara, CA
- Weather: 54 degrees, 60% chance of precipitation, 8-mph winds
Buccaneers vs. 49ers Odds
Buccaneers vs. 49ers Odds Analysis
The spread opened with the 49ers favored by 6 points, but dropped to 3.5 when Niners quarterback Jimmy Garoppolo was lost for the season with a broken foot. Backup QB Purdy still managed to lead San Fran to victory over the Miami Dolphins, but he'll now make his first career start opposite a quarterback with seven Super Bowl rings.
The quarterback change also caused the total to drop from an opening 41.5 points to 38.5. At sportsbooks such as Caesars and PointsBet, the total stands at 38, but DraftKings, FanDuel and BetMGM still carry the hook.
Buccaneers vs. 49ers Pick
Under 37.5 ★★★★
The Buccaneers remain a dead Under team, as the Over hit in just two of their 12 games this season.
The Under is 4-0 in the Bucs' last four games and 5-0 in their last five road games.
At this point in the season, it's clear the drop off in Tampa's offense isn't an aberration. The team struggles to reach even 20 points in a given game, and those difficulties will be exacerbated against a ferocious 49ers' defense.
The Niners have a 5-7 Over/Under record and should further struggle to score with Purdy at the controls against a Bucs D that ranks fifth in opponent PPG. Add to the mix that offensive stars running back Christian McCaffrey (knee) and wide receiver Deebo Samuel (quad) were limited in practice with nagging injuries and points could be at a premium Sunday.
Buccaneers vs. 49ers Best Odds
PointsBet (-107)
| DraftKings | FanDuel | BetMGM | Caesars | PointsBet |
| 37 | 37.5 | 37.5 | 37.5 | 37.5 |
| O/U -110 | O -105/U -115 | O/U -110 | O/U -110 | O/U -107 |
Go to PointsBet to get the best odds of -107 for the 37.5 total. BetMGM and Caesars offer 37.5 at -110 odds and FanDuel's odds sit at -115.
Where to Bet on Buccaneers vs. 49ers Picks
Buccaneers - 49ers picks made 12/9/2022 at 9:22 a.m. ET.
