Brock Purdy Player Props vs. Panthers: Can Carolina Stop Purdy On Monday Night Football?
Last Updated: November 24, 2025 7:03 PM EST • 3 minute read X Social Google News Link
Get set for prime-time football between the Panthers and 49ers with my best Brock Purdy player props. Lock these in before the 8:15 p.m. ET kickoff from Levi's Stadium in San Francisco (ESPN) as part of our NFL predictions for Week 12.
The 49ers come into tonight as 7.5-point favorites - can Purdy lead the offense to another explosive outcome after dropping 41 points just a week ago? Let's take a look at why I'm fading him tonight.
✅ Brock Purdy player prop bets vs. Panthers
See all of our NFL picks for Week 12 based on the latest NFL odds.
💵 Best Brock Purdy player props
💰 Best Brock Purdy player prop picks: Play of the Day (2u)
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⬇️ Brock Purdy Under 250.5 passing yards (-114) ⭐⭐⭐⭐
Carolina’s pass defense is quietly pretty solid, giving up only 212 yards a game through the air. Meanwhile, Brock Purdy is still shaking off the rust after returning from injury - he went 19-of-26 for just 200 yards last week against a shaky Arizona defense. Expect San Francisco to lean heavily on Christian McCaffrey to drive the offense once more, leaving Purdy short on both time and pass attempts to clear this line. It doesn’t hurt our case that the 49ers’ wide receiver room isn’t exactly overflowing with firepower right now, either.
I'm doubling down on this one as part of my best Panthers vs. 49ers player props for Monday Night Football, too.
You're getting the best price at FanDuel for this prop, and you're also getting some value, as I'd price this play closer to -120. Fire this up as part of our best Brock Purdy player props for Monday Night Football.
💰 Best Brock Purdy player prop picks: 1u pick
⬆️ Brock Purdy Over 36.5 longest pass (-114) ⭐⭐⭐
I know we're threading the needle here after taking the Under in his overall passing yards, and Purdy has gone over this number just once in his three starts this season, but the Panthers have been prone to splash plays all year, especially in the last three weeks. Michael Penix connected with a 41-yard pass last week, Tyler Shough dropped a 62-yard bomb against them the game prior, and Jordan Love went for 52 yards in Week 9. Look for Purdy to do the same in the first half.
You're getting the best price at FanDuel for this prop once again - this is a 1u play for me prior to kickoff.
💡 More Panthers vs. 49ers picks: Monday Night Football
💡 More Week 12 predictions
Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for Week 12.
🚀 Best Brock Purdy SGP bets
💵 Brock Purdy same-game parlay picks
- 1st leg: Under 250.5 passing yards (-114)
- 2nd leg: Over 36.5 longest pass (-114)
- 3rd leg: Under 9.5 rushing yards (-114)
Best odds: +561 via FanDuel ($10 to win $56.10)
📺 How to watch Monday Night Football: Panthers vs. 49ers
- Date: Monday, Nov. 24
- Kickoff: 8:15 p.m. ET
- Location: Levi's Stadium (Santa Clara, Calif.)
- TV: ESPN
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- Brock Purdy player props
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