Bills vs. Texans Best Bets: Our Staff Expert Picks for Thursday Night Football
Thursday Night Football kicks off tonight at 8:15 p.m. ET (Prime Video) when the Buffalo Bills (7-3) and Houston Texans (5-5) face off at NRG Stadium in Houston, and we've gathered our Bills vs. Texans best bets from our NFL staff with their TNF expert picks as part of our NFL Week 12 predictions.
🏈 Bills vs. Texans best bets & TNF expert picks
See all of our NFL picks for every game based on the latest NFL odds.
| Wager type | Best bet | Best odds |
|---|---|---|
| Game prediction | Texans +6 | -110 via BetMGM |
| Over/Under pick | Under 43.5 | -105 via BetMGM |
| Best player prop bet | James Cook Under 75.5 rushing yards | -115 via BetMGM |
| Best anytime TD pick | Josh Allen anytime TD | -118 via Caesars |
| Best first TD pick | Woody Marks first TD | +750 via Caesars |
💡 More NFL predictions
Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game this season.
🔮 Bills vs. Texans prediction
The Bills enter Thursday Night Football in desperate need of a road win to keep pace with the New England Patriots in the AFC East standings, but our NFL expert Gary Pearson expects the host Texans to give them a run for their money tonight at NRG Stadium.
Pearson is taking the points on Houston thanks to its dominant defense, which should fluster one of the NFL's most clutch QBs in what he expects to be a low-scoring affair. He breaks down his full analysis for this matchup, along with his best bets in every key market, in his Bills vs. Texans prediction.
💵 Thursday Night Football predictions
- Game prediction: Texans +6 (-110) ⭐⭐⭐⭐
- Over/Under pick: Under 43.5 (-105) ⭐⭐⭐
- Best prop bet: Josh Allen Over 31.5 rushing yards (-114) ⭐⭐⭐⭐
🔥 Bills vs. Texans player props
Houston's defense is a defining factor in tonight's matchup, as Pearson broke down in his full-game preview. And our NFL expert Matt Jacob is also backing DeMeco Ryans' unit to make life difficult for Josh Allen and Co. in a tough road spot.
Jacob is fading both Allen and his star running mate, James Cook, as he bets the Under on both of their player prop bets. He's more optimistic about the Texans' chances to move the ball tonight with the ground game, as he breaks down in his Bills vs. Texans player props.
Our NFL expert Dustin Saracini is also diving even deeper into the player prop market for this TNF matchup in Houston, as he offers his best Josh Allen player props for the Bills QB along with his favorite Davis Mills player props on the Texans' side.
💵 Thursday Night Football player props
- James Cook III player prop: Under 75.5 rushing yards (-115) ⭐⭐⭐⭐⭐
- Woody Marks player prop: Over 61.5 rushing yards (-110) ⭐⭐⭐
- Josh Allen player prop: Under 225.5 passing yards (-113) ⭐⭐
💪 Bills vs. Texans anytime TD pick
Our NFL expert Corey Scott makes his prime-time debut for his anytime TD picks ahead of Bills vs. Texans, and he's taking a shot on two unheralded role players tonight to reach the end zone at NRG Stadium.
Scott is betting on Allen to score his 11th rushing touchdown of the season, but he's also taking a shot on Woody Marks and Jackson Hawes with his anytime touchdown scorer predictions for Thursday Night Football.
💵 Thursday Night Football anytime TD picks
- Josh Allen TD pick: To score anytime TD (-118) ⭐⭐⭐⭐⭐
- Woody Marks TD pick: To score anytime TD (+129) ⭐⭐⭐⭐
- Jackson Hawes TD pick: To score anytime TD (+1000) ⭐⭐⭐
🥇 Bills vs. Texans first TD pick
Our NFL expert Sean Tomlinson has been money with his first TD picks this year, and he's back on the beat tonight as he looks for the likeliest players to break a scoreless tie tonight on Thursday Night Football.
Like our other experts, Tomlinson is high on Marks tonight to make an impact against a shoddy Bills defense, and he's also taking a shot on Allen and one of his underappreciated deep threats as part of his first touchdown scorer predictions for Thursday Night Football.
💵 Thursday Night Football first TD picks
- Woody Marks TD pick: To score first TD (+750) ⭐⭐⭐⭐
- Josh Allen TD pick: To score first TD (+525) ⭐⭐⭐⭐
- Josh Palmer TD pick: To score first TD (+2000) ⭐⭐⭐
🚀 Bills vs. Texans same-game parlay
Our NFL expert Brenden Schaeffer has put together another prime-time same-game parlay, this time with three player prop bets on some of the biggest stars on the field tonight. Schaeffer is backing Cook and fellow rusher Nick Chubb while fading Dalton Schultz with his Bills vs. Texans same-game parlay for Thursday Night Football.
💵 Thursday Night Football same-game parlay (SGP)
- 1st leg: Dalton Schultz Under 4.5 receptions (-141) ⭐⭐⭐⭐⭐
- 2nd leg: Nick Chubb Over 22.5 rushing yards (-109) ⭐⭐⭐⭐⭐
- 3rd leg: James Cook anytime TD scorer (-105) ⭐⭐⭐⭐
Best odds: +525 via DraftKings ($10 to win $52.50)
📺 How to watch Thursday Night Football: Bills vs. Texans
- Date: Thursday, Nov. 20
- Kickoff: 8:15 p.m. ET
- Location: NRG Stadium (Houston)
- TV: Prime Video
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