Anytime Touchdown Scorer Predictions for Monday Night Football: Panthers vs. 49ers TD Picks

Who's getting into the end zone on Monday Night Football? Dive into my anytime touchdown scorer predictions for Panthers vs. 49ers.
Carolina Panthers wide receiver Tetairoa McMillan - who's featured in our Panthers vs. 49ers anytime touchdown predictions for Monday Night Football - celebrates a touchdown.
Pictured: Carolina Panthers wide receiver Tetairoa McMillan - who's featured in our Panthers vs. 49ers anytime touchdown predictions for Monday Night Football - celebrates a touchdown. Photo by: Brett Davis-Imagn Images
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Are you ready for prime time? Get set with our Panthers vs. 49ers anytime touchdown scorer predictions for Monday Night Football from Levi's Stadium in San Francisco (NBC) as part of our NFL predictions for Week 12.

The 49ers come into the 8:15 p.m. kickoff as 7.5-point favorites - can their offense continue to put points on the board after dropping 41 just a week ago? Let's dive in.


✅ Anytime touchdown scorer predictions: Panthers vs. 49ers

See all of our experts' NFL picks for Week 12.

💵 Best Monday Night Football anytime TD picks

  • Rico Dowdle TD pick: To score anytime TD (-137 via Caesars) ⭐⭐⭐⭐⭐
  • Tetairoa McMillan TD pick: To score anytime TD (+150 via bet365) ⭐⭐⭐⭐
  • George Kittle TD pick: To score anytime TD (+140 via bet365) ⭐⭐⭐⭐

💰 Best Monday Night Football anytime touchdown scorer bets

🔥 Rico Dowdle, RB, Panthers (-137) ⭐⭐⭐⭐⭐

San Francisco is a bottom-10 red-zone defense, allowing teams to score at a 58.97% clip over 11 weeks of the season. Taking a back seat to Chubba Hubbard for most of the season, Dowdle is still 15th in the NFL in red-zone attempts and has scored three touchdowns inside the 5-yard line. In a game projected for nearly 50 points, expect the Panthers to visit the red zone several times, and for Dowdle to be getting the lions' share of the workload when they do.

Head to Caesars for this play, as its -137 betting odds are the best value among our best sports betting sites. Popular sportsbooks like FanDuel are offering this play at -150, which is what I'd price it at.

🔥 Tetairoa McMillan, WR, Panthers (+150) ⭐⭐⭐⭐

McMillan is the undisputed No. 1 option in Carolina, and for good reason. He sucks up targets, totaling 36 over his last four games, and is their top receiving threat, scoring two touchdowns just last week. He's got four touchdowns on the season, but if the game script flips with the 49ers leading, expect McMillan to play a huge role tonight for the Panthers.

All sportsbooks are essentially locked in at, or close to, +150 betting odds. Play these odds before they get closer to +135 prior to kickoff.

🔥 George Kittle, TE, 49ers (+140) ⭐⭐⭐⭐

Kittle scoring on prime-time football is like pancakes with maple syrup; they just go together perfectly. If you're Canadian, you understand where I'm coming from. Kittle is an incredible threat inside the 20, catching eight balls with a 100% catch rate. He's truly a nightmare for opposing defenses.

With three scores on 15 targets over his last two games, and all of his five scores coming inside the 20-yard line, look for Brock Purdy - who's a part of our best Panthers vs. 49ers player props - to find him when they make their trips to the red zone tonight.

The line at bet365 is substantially better across all of our best sports betting apps, with top books like DraftKings pricing this play at +120.

💡 More NFL predictions

Want more NFL betting advice? Check out all of our NFL analysis and expert predictions for every game this season.


📊 Anytime touchdown scorer odds: Panthers vs. 49ers

See live NFL odds for every game this season.

🔍️ Find the best odds for every bet

Search the best NFL player prop odds for any team or player across every market from legal sportsbooks in your area.


📺 How to watch Monday Night Football: Panthers vs. 49ers

  • Date: Monday, Nov. 24
  • Kickoff: 8:15 p.m. ET
  • Location: Levi's Stadium (Santa Clara, Calif.)
  • TV: ESPN

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