Anytime Touchdown Scorer Predictions for Thursday Night Football: Cowboys vs. Lions TD Picks

The Dallas Cowboys (6-5-1) and Detroit Lions (7-5) meet tonight at Ford Field (8:15 p.m. ET, Prime Video) in the first game of NFL Week 14. My anytime touchdown scorer predictions for Thursday Night Football offer up three plus-money picks, with a focus on Lions wide receiver Isaac TeSlaa (+170), and a 16-1 long shot.

Anytime touchdown scorer predictions: Cowboys vs. Lions

See all of our experts' NFL picks for Week 14 based on the latest NFL odds.

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Isaac TeSlaa, WR, Lions (+170) ⭐⭐⭐⭐⭐

Isaac TeSlaa, a rookie third-round pick from the 2025 draft, has just six receptions (11 targets) on the season, but he's scored three touchdowns, including one on Thanksgiving. He caught both of his targets for 35 yards against the Packers while playing 92% of the offensive snaps.

That expanded playing time came with tight end Sam LaPorta already sidelined and Amon-Ra St. Bown - the Lions leader in nearly every receiving stat, including 20 red-zone targets - leaving the game early due to injury. St. Brown is considered questionable for Thursday Night Football due to the lingering ankle injury.

TeSlaa is already tied for second among Lions receivers with four red-zone targets (second with three receptions), and is second with three touchdowns inside the 20-yard line. Take the +170 odds from Caesars for a $17 profit on a winning $10 bet if he scores for the second straight week.

Our Matt Jacob sees the path to a less productive outing for the Lions' lead running back with his Cowboys vs. Lions player props, and this could lead to even more work for TeSlaa.

Dak Prescott, QB, Cowboys (+650) ⭐⭐⭐

We're taking advantage of outlier +650 odds from DraftKings for this long-shot anytime touchdown scorer prediction. The +650 odds for Dak Prescott to score his third rushing touchdown of the season would return a $65 profit on a winning $10 bet - $10 more than the +550 odds from FanDuel would return.

The Lions have given up three rushing touchdowns to opposing QBs this season, and nobody has given up more than their 68 rushing attempts to the position. Cowboys running back Javonte Williams hasn't scored on the ground in four straight weeks and averaged just 3.5 yards per carry on 17 attempts on Thanksgiving.

Dallas should be looking to get creative for a spark in the running game, and Prescott can keep it in his own hands near the goal line.

Jalen Tolbert, WR, Cowboys (+1600) ⭐⭐⭐

Jalen Tolbert's playing time has been wildly inconsistent in what's a mediocre Cowboys receiver room behind CeeDee Lamb and breakout star George Pickens. The former third-round pick played 18 offensive snaps (25%) on Thanksgiving for his highest single-game total since Week 7.

He has largely slipped behind Ryan Flournoy and KaVontae Turpin on the depth chart, but it's not like the other two are stuffing the stat sheet on a regular basis. Tolbert is still averaging 12.3 yards per reception from 14 catches (25 targets). And he led the team with seven receiving touchdowns last year.

The Lions' 19 touchdowns surrendered to receivers are more given up to the position than all but the Cowboys (21) through 12 games. I'm willing to take these long-shot +1600 odds for Tolbert to score in a game with a lofty Over/Under of 54.5 points tonight.

Our Gary Pearson makes the case for a big game from Pickens with his Cowboys vs. Lions prediction.

Cowboys vs. Lions anytime touchdown scorer parlay

See all of our NFL touchdown props for Thursday Night Football and more.

Anytime touchdown scorer odds: Cowboys vs. Lions

How to watch Thursday Night Football: Cowboys vs. Lions

• Date: Thursday, Dec. 4
• Kickoff: 8:15 p.m. ET
• Location: Ford Field (Detroit)
• TV: Prime Video