49ers vs. Seahawks Player Props & Best Bets Tonight
My best 49ers vs. Seahawks player props include Christian McCaffrey, Brock Purdy, and Sam Darnold as part of our NFL Divisional Round predictions tonight.
Kickoff is at 8 p.m. ET tonight from Lumen Field in Seattle (FOX), with the Seahawks favored by 7 points as the biggest betting favorite of the Divisional Round.
🏈 49ers vs. Seahawks player props today: NFL Divisional Round
See the latest NFL odds and our experts' NFL picks for every game this season.
| Player | Prop bet | Best odds | Confidence |
|---|---|---|---|
| Christian McCaffrey, RB, 49ers | Over 50.5 receiving yards | -115 via DraftKings | ⭐⭐⭐⭐⭐ |
| Sam Darnold, QB, Seahawks | Under 1.5 passing TDs | -109 via DraftKings | ⭐⭐⭐⭐ |
| Brock Purdy, QB, 49ers | Over 22.5 completions | -105 via DraftKings | ⭐⭐⭐⭐ |
💰 49ers vs. Seahawks best prop bet: Christian McCaffrey Over 50.5 receiving yards (-115) ⭐⭐⭐⭐⭐
Follow all of our NFL analysis and betting advice for the 2026 NFL playoffs.
Christian McCaffrey is well-positioned to take advantage of the Seahawks' tendency to allow running backs to get involved in the passing game.
Seattle allowed the NFL's most targets and receptions to the position, alongside the sixth-most receiving yards. And San Francisco's inefficiency rushing the football has forced McCaffrey into his heaviest workload as a pass-catcher in years.
I'm placing my wager at DraftKings, which offers a lower total than FanDuel at similar odds. McCaffrey is also one of our best values in the latest 49ers vs. Seahawks prediction market for the Divisional Round.
🔥 More 49ers vs. Seahawks prop picks tonight
Sam Darnold Under 1.5 passing TDs (-109) ⭐⭐⭐⭐
Sam Darnold didn't throw a single touchdown pass in either of the first two matchups this season against San Francisco. Seattle emphasized the running game in the Week 18 win, in particular, leaning on the two-headed monster of Zach Charbonnet and Kenneth Walker III.
Win or lose, I see that strategy continuing for the Seahawks on Saturday, making it unlikely that Darnold throws multiple touchdowns. That game script plays right into what we expect to happen in our 49ers vs. Seahawks prediction for tonight.
We're keeping an eye on Darnold's injury status as he battles an oblique injury ahead of tonight's game.
Brock Purdy Over 22.5 completions (-105) ⭐⭐⭐⭐
You have to take your advantages against an elite Seahawks defense where you can: Seattle allowed the ninth-most completions in the regular season.
Brock Purdy will have to remain patient against a Seahawks team that takes away the deep ball better than anyone else, and that should lead to him going Over his completions total.
💰️ 49ers vs. Seahawks expert picks
📈 49ers vs. Seahawks: Latest odds
Latest odds for Bills vs. Broncos via BetMGM.
The Seahawks have remained a 7-point betting favorite all week, while the total has been stuck on 44.5 for the last several days. I anticipate the line staying where it's been up until kickoff.
🚀 49ers vs. Seahawks same-game parlay
See all of our NFL same-game parlays for the Divisional Round, and our best NFL parlay betting sites.
- Christian McCaffrey Over 50.5 receiving yards
- Sam Darnold Under 1.5 passing TDs
- Brock Purdy Over 22.5 completions
Best SGP odds: +600 via DraftKings
📺 How to watch 49ers vs. Seahawks tonight: NFL Divisional Round
- Date: Saturday, Jan. 17
- Kickoff: 8 p.m. ET
- Location: Lumen Field (Seattle)
- TV: FOX
💡 NFL Divisional Round expert picks
- NFL picks against the spread for Divisional Round
- NFL AI predictions for Divisional Round
- NFL weather report for Divisional Round
- NFL playoff QB power rankings for Divisional Round
- NFL upset picks for Divisional Round
- NFL best bets for Divisional Round
- Divisional Round picks to win
- Conference championship look-ahead odds
- Free printable NFL playoff bracket
- NFL playoff bracket predictions
- NFL player props for Divisional Round
- NFL anytime touchdown scorer predictions for Divisional Round
- NFL anytime touchdown scorer parlay for Divisional Round
- NFL long-shot parlay for Divisional Round
- How to live bet the Divisional Round
- NFL first touchdown scorer predictions for Divisional Round
- NFL score predictions for Divisional Round
📃 Affiliate disclosure
Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)
Related Articles
