49ers vs. Seahawks Player Props & Best Bets: NFL Divisional Round Prop Bets
Last Updated: January 16, 2026 6:00 PM EST • 2 minute read Google News Link
My favorite 49ers vs. Seahawks player props feature Christian McCaffrey, Brock Purdy, and Sam Darnold as part of our NFL Divisional Round predictions.
Kickoff is at 8 p.m. ET on Saturday from Lumen Field in Seattle (FOX), with the Seahawks the largest betting favorite of the week at 7 points.
🏈 49ers vs. Seahawks player props: NFL Divisional Round
See the latest NFL odds and our experts' NFL picks for every game this season.
| Player | Prop bet | Best odds | Confidence |
|---|---|---|---|
| Christian McCaffrey, RB, 49ers | Over 50.5 receiving yards | -115 via DraftKings | ⭐⭐⭐⭐⭐ |
| Sam Darnold, QB, Seahawks | Under 1.5 passing TDs | -109 via DraftKings | ⭐⭐⭐⭐ |
| Brock Purdy, QB, 49ers | Over 22.5 completions | -105 via DraftKings | ⭐⭐⭐⭐ |
💰 49ers vs. Seahawks best prop bet: Christian McCaffrey Over 50.5 receiving yards (-115) ⭐⭐⭐⭐⭐
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Christian McCaffrey is well-positioned to take advantage of the Seahawks' tendency to allow running backs to get involved in the passing game.
Seattle allowed the NFL's most targets and receptions to the position, alongside the sixth-most receiving yards. And San Francisco's inefficiency rushing the football has forced McCaffrey into his heaviest workload as a pass-catcher in years.
I'm placing my wager at DraftKings, which offers a lower total than FanDuel at similar odds.
🔥 More 49ers vs. Seahawks prop picks
Sam Darnold Under 1.5 passing TDs (-109) ⭐⭐⭐⭐
Sam Darnold didn't throw a single touchdown pass in either of the first two matchups this season against San Francisco.
Seattle emphasized the running game in the Week 18 win, in particular, leaning on the two-headed monster of Zach Charbonnet and Kenneth Walker III.
Win or lose, I see that strategy continuing for the Seahawks on Saturday, making it unlikely that Darnold throws multiple touchdowns.
Brock Purdy Over 22.5 completions (-105) ⭐⭐⭐⭐
You have to take your advantages against an elite Seahawks defense where you can: Seattle allowed the ninth-most completions in the regular season.
Brock Purdy will have to remain patient against a Seahawks team that takes away the deep ball better than anyone else, and that should lead to him going Over his completions total.
🚀 49ers vs. Seahawks same-game parlay
See all of our NFL same-game parlays for the Divisional Round, and our best NFL parlay betting sites.
- Christian McCaffrey Over 50.5 receiving yards
- Sam Darnold Under 1.5 passing TDs
- Brock Purdy Over 22.5 completions
Best SGP odds: +600 via DraftKings
📺 How to watch 49ers vs. Seahawks: NFL Divisional Round
- Date: Saturday, Jan. 17
- Kickoff: 8 p.m. ET
- Location: Lumen Field (Seattle)
- TV: FOX
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