🏀 March Madness Predictions Sunday: Expert Picks & Odds for Round 2
Last Updated: March 22, 2026 5:00 AM EDT • 4 minute read X Social Google News Link
It's the final day of college basketball action of the opening weekend of the NCAA Tournament, and our March Madness predictions for Sunday include our best bets for all eight games on the slate.
Day 4 of the NCAA Tournament gives us another 12 hours of college basketball with Sweet 16 berths on the line, and we've got you covered with our March Madness bracket predictions for every matchup.
🕒 Sunday's March Madness schedule
Today's second-round slate:
| Favorite | Underdog | Time | Location |
|---|---|---|---|
| (2) Purdue -7.5 | (7) Miami | 12:10 p.m. ET | Enterprise Center (St. Louis) |
| (2) Iowa State -4.5 | (7) Kentucky | 2:45 p.m. ET | Enterprise Center (St. Louis) |
| (5) St. John's -3.5 | (4) Kansas | 5:15 p.m. ET | Viejas Arena (San Diego) |
| (6) Tennessee -1.5 | (3) Virginia | 6:10 p.m. ET | Xfinity Mobile Arena (Philadelphia) |
| (1) Florida -10.5 | (9) Iowa | 7:10 p.m. ET | Benchmark International Arena (Tampa, Fla.) |
| (1) Arizona -11.5 | (9) Utah State | 7:50 p.m. ET | Viejas Arena (San Diego) |
| (2) UConn -4.5 | (7) UCLA | 8:45 p.m. ET | Xfinity Mobile Arena (Philadelphia) |
| (4) Alabama -1.5 | (5) Texas Tech | 9:45 p.m. ET | Benchmark International Arena (Tampa, Fla.) |
🔎 March Madness predictions: Sunday
Check out the latest March Madness odds and Final Four odds.
Miami vs. Purdue odds & predictions
Miami vs. Purdue prediction: Purdue -7.5
"Miami tried every which way to give away its game against Missouri, and the Tigers simply ran out of steam and failed to execute the little things. I don't see Purdue making similar mistakes. The Boilermakers put up triple-digit points on Friday. Miami's 144th-ranked opposing field-goal percentage won't hold up against this Purdue offense." - via Brenden Schaeffer
Kentucky vs. Iowa State odds & predictions
Kentucky vs. Iowa State prediction: Iowa State -4.5
"Kentucky has largely taken care of the basketball lately behind solid play from Denzel Aberdeen, but after a handsy Santa Clara team turned over the Wildcats 11 times on Friday, I have concerns in a matchup against an Iowa State team that forces 15.3 turnovers per game (No. 5 in the nation)." - via Brenden Schaeffer
St. John's vs. Kansas odds & predictions
St. John's vs. Kansas prediction: St. John's -3.5
"Though Kansas ranks eighth in adjusted defensive rating, according to KenPom, St. John's has scored at least 72 points in 11 of its last 12 games. St. John's also ranks 11th in defensive adjusted rating, and the Red Storm defense is going to be too much for Kansas' 58th-ranked offense to overcome." - via Phil Wood
Tennessee vs. Virginia odds & predictions
Tennessee vs. Virginia prediction: Virginia ML
"Virginia poses other issues, but the most glaring is how well it is set up to defend Tennessee inside. The Volunteers rank in the 89th-percentile in post-ups and the 86th percentile in efficiency, but the Cavaliers’ elite rim protection ranks fifth in 2-point percentage allowed." - via Mike Spector
Iowa vs. Florida odds & predictions
Iowa vs. Florida prediction: Iowa +10.5
"Iowa could realistically pull this upset for two reasons. First, Iowa ranks fifth-slowest in adjusted tempo according to KenPom, which will limit Florida's possessions. Second, Iowa has the 26th-best shooting percentage in the country, averaging 48.8% from the floor. Iowa has lost by single digits to Iowa State, Illinois, Purdue, and Michigan this season, while also totally instilling its will in a 57-52 win over Nebraska." - via Phil Wood
Utah State vs. Arizona odds & predictions
Utah State vs. Arizona prediction: Arizona -12.5
"Arizona only makes 5.9 3-pointers per game, but the Wildcats are shooting 36.3% from deep, which ranks 50th in the country. Utah State ranks 229th in 3-point defense, and in the first round, Villanova was 14-of-30 from long range." - via Phil Wood
UCLA vs. UConn odds & predictions
UCLA vs. UConn prediction: UCLA +4.5
"The Bruins' offense entered the tournament playing at a top-10 level over the last month. It is no secret why UCLA’s offense is humming, as Dent has an unfathomable 13.8 assist-to-turnover ratio over his last nine games. For as many eye-popping tournament trends Dan Hurley has, UCLA had a solid 60% cover rate against ranked opponents this season." - via Mike Spector
Texas Tech vs. Alabama odds & predictions
Texas Tech vs. Alabama prediction: Alabama -1.5
"Alabama is averaging 91.7 points per game, and in their first game without Aden Holloway, the Crimson Tide scored 90 against Hofstra. Four Alabama players scored in double figures, including Labaron Philon Jr., who scored 29." - via Phil Wood
📅 March Madness key dates
Selection Sunday: March 15First Four: March 17-18 (Dayton, Ohio)First round: March 19-20- Second round: March 21-22
- Sweet 16: March 26-27
- Elite Eight: March 28-29
- Final Four: Saturday, April 4
- National championship game: Monday, April 6
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Rob Paul X social