Yankees vs. Blue Jays Prediction Tonight: Best Bets & Odds for AL East Clash

Toronto has won 10 consecutive games at Rogers Centre coming into tonight. Can the Blue Jays stay hot against the Yankees?

Gabe Henderson

Last Updated: July 21, 2025 3:50 PM EDT • 4 minute read

Yankees vs. Blue Jays Prediction Tonight: Best Bets & Odds for July 21 — Pictured: Toronto Blue Jays starting pitcher Kevin Gausman (34) - an important piece in our Yankees vs. Blue Jays prediction tonight - throws a pitch. Photo by Dennis Lee via Imagn Images.

Toronto is on the verge of franchise history, and my Yankees vs. Blue Jays prediction anticipates a record-breaking night at Rogers Centre against New York.

First pitch is scheduled for 7:07 p.m. ET (Sportsnet, YES Network) from Rogers Centre in Toronto. Our best sports betting sites list the Yankees as road betting favorites (-118) behind Cy Young Award odds long shot Carlos Rodon.

My Yankees vs. Blue Jays best bets side with the underdogs amid their 10-game home winning streak. I also focus on Aaron Judge, who is the subject of one of the top plays in Andrew Brennan's best home run predictions today.

Yankees vs. Blue Jays prediction: Blue Jays to win (+102 via FanDuel) ⭐⭐⭐
Best Yankees vs. Blue Jays player props: Aaron Judge Over 1.5 bases (+100 via DraftKings) ⭐⭐⭐⭐

⚾ Yankees vs. Blue Jays prediction & odds

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🧐 Yankees vs. Blue Jays betting insights

Here is how the public is betting Yankees vs. Blue Jays tonight at BetMGM:

Team	Run Line	Moneyline	Confidence
Yankees	40% (-1.5, +140)	63% (-120)	⭐⭐
Blue Jays	60% (-1.5, -165)	37% (+100)	⭐⭐⭐

💰 Yankees vs. Blue Jays prediction & best bet

✅ Yankees vs. Blue Jays prediction: Blue Jays to win (+102 via FanDuel)

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Bet against the Blue Jays at your discretion, but my Yankees vs. Blue Jays prediction won't recommend fading the best home team in baseball anytime soon.

Toronto has won 10 consecutive contests at Rogers Centre, so while the pitching matchup may favor the visitors, I'm not passing up on a chance to take the hosts at plus-money odds. The Blue Jays are MLB's best home team, posting a 35-16 record in front of their home crowd.

Meanwhile, New York struggles away from the friendly confines of Yankee Stadium. The Yankees are just .500 for the season (25-25) on the road despite a consistent scoring output. Aaron Boone's arms give up nearly an entire run more per game on the road (4.54) than at home (3.69).

My Yankees vs. Blue Jays best bet looks to take advantage of New York's inconsistent pitching performances. If Toronto wins tonight, it not only sets a franchise record of consecutive home wins but also rewards bettors with a $10.20 profit on a $10 wager.

💰 Best Yankees vs. Blue Jays player props

✅ Best Yankees vs. Blue Jays player prop: Aaron Judge Over 1.5 bases (+100 via DraftKings)

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Few batters have beaten up Kevin Gausman as frequently as Aaron Judge. The same can be said for many of the AL MVP odds favorite's counterparts, but he's found specific success against Toronto's veteran over the years.

Judge is hitting .372 against Gausman across 43 career at-bats with nine of those 16 hits being extra-base hits. The slugger has gone Over 1.5 bases at a 40% clip over his past 10 games.

Judge's historical success against Gausman and his scorching hot form are why this even-money pick at our best sports betting apps is my best Yankees vs. Blue Jays player prop.

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❓MLB betting FAQs

How do betting odds work?

Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common.

What is the run line in baseball?

The run line in baseball is a form of point spread betting unique to MLB. It typically sets a standard spread of 1.5 runs, meaning the favored team must win by at least two runs to cover the run line, while the underdog can lose by one run or win outright to cover.

What does moneyline mean in betting?

The moneyline in betting refers to a wager on which team or player will win the game outright, with no point spread involved. It’s the most straightforward type of sports bet - just pick the winner.

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Written by:
Gabe Henderson

Gabe Henderson is a sports betting writer from Houston, Texas. He graduated from Louisiana State University in 2022 with a bachelor's degree in Mass Communication. Gabe developed an interest in sports betting while in college due to its legalization in Louisiana. He turned his passion into a career shortly after, joining The Advocate/NOLA.com as a Sports Betting Content Coordinator, where he spent two years. Gabe wore many hats before graduating as he led FanSided's coverage of Chelsea FC as a Site Expert with "The Pride of London." He was also the Editor-in-Chief of the LSU Gumbo Yearbook for two years. Gabe became a part of the SportsbookReview.com team in late 2024. He brings with him an extensive knowledge of many sports, including — but not limited to — NFL, NCAA, MLB, NBA, soccer, and UFC.