Red Sox vs. Blue Jays Prediction, Odds & Expert Picks: MLB Best Bets for Tonight Sept. 23

I expect some fireworks when two of the league's best offenses square off today at Rogers Centre in Toronto.
Red Sox vs. Blue Jays Prediction, Odds & Expert Picks: MLB Best Bets for Sept. 23
Pictured: Lucas Giolito pitches against the Arizona Diamondbacks at Chase Field. Photo by Arianna Grainey via Imagn Images

Boston and Toronto are two of the better offensive clubs in MLB, and my Red Sox vs. Blue Jays prediction expects both teams to live up to their reputation. First pitch is set for 7:07 p.m. ET tonight from Rogers Centre in Toronto (Local TV).

For my MLB picks, Red Sox outfielder Jarren Duran has an advantageous matchup at the plate, and I've honed in on the Over for one of his player props.


⚾ Red Sox vs. Blue Jays expert picks & predictions

MLB expert picks for Tuesday; odds subject to change.

  • Moneyline pick: Red Sox (+145 via BetMGM) ⭐⭐
  • Run line pick: Red Sox +1.5 (-155 via BetMGM) ⭐⭐⭐
  • Over/Under pick: Over 8 (+100 via FanDuel) ⭐⭐⭐

📝 Red Sox vs. Blue Jays preview & best bet

Track the latest MLB scores for line movement and matchup info.

⬆️ Over 8 (+100) ⭐⭐⭐

Red Sox vs. Blue Jays Prediction, Odds & Expert Picks: MLB Best Bets for Sept. 23
Pictured: George Springer hits a home run against the Kansas City Royals. Photo by Jay Biggerstaff via Imagn Images

The Blue Jays have been in an offensive rut of late, but they are a completely different team when playing in front of their home fans at the Rogers Centre. They are third in OPS, second in batting average, and fifth in runs scored at home this season.

The Red Sox, meanwhile, are eighth in MLB in OPS, sixth in runs scored, and fourth in batting average. They have also performed well on the road, ranking inside the top 10 in road OPS and runs scored.

Even with a matchup featuring two excellent pitchers in Lucas Giolito and Kevin Gausman, I still expect two of the best offensive clubs to churn out hits and runs in an environment that has been a catalyst for offensive production this season.

One of the best betting sites, FanDuel, offers +100 odds on Over 8 runs, which would profit $10.00 on a winning $10 bet. The +100 odds have an implied probability of 50%.

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💰 Best Red Sox vs. Blue Jays player prop bet

Our MLB player prop odds tool shows the best odds for every market across legal sportsbooks in your area.

⬆️ Jarren Duran Over 1.5 hits, runs, and RBI (-106) ⭐⭐⭐

Red Sox vs. Blue Jays Prediction, Odds & Expert Picks: MLB Best Bets for Sept. 23
Pictured: Jarren Duran hits a two-run home run against the Tampa Bay Rays. Photo by Kim Klement Neitzel via Imagn Images

Duran is hot, hitting .310 with five runs scored, one home run, and two RBIs over his last seven games. He has a .309 average and .527 slugging percentage against offspeed pitches, which should be helpful against Gausman's devastating splitter. 

Duran has historically loved his time hitting at Rogers Centre, slashing .355/.365/.629 with three home runs, seven RBIs, 10 runs scored, and six doubles over 14 games.

A $10 winning bet on Duran’s Over pays a profit of $9.43 at DraftKings, and the -106 odds have an implied probability of 51.46%.

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📊 Red Sox vs. Blue Jays odds: Sept. 23

MLB odds update live in real time.

📈 Red Sox vs. Blue Jays betting odds analysis

Toronto opened as high as the -165 home betting favorite, with some of the best sports betting apps offering them as low as -175. I’d be happy to grab a Red Sox team that's 5-3 over its last eight road contests on the moneyline. BetMGM offers the best value at +145. 


🔢 Red Sox vs. Blue Jays stats

Season stats courtesy of baseball-reference.com.

Red Sox (85-71) Statistic (per game) Blue Jays (90-66)
4.90 Runs 4.92
8.76 Hits 9.06
.255 AVG .267
.423 SLG .427
.748 OPS .761
3.76 ERA 4.23
8.46 K/9 8.92
3.28 BB/9 3.23
1.03 HR/9 1.33

🚑 Red Sox vs. Blue Jays injuries


📺 Red Sox vs. Blue Jays game info

  • When: Tuesday, Sept. 23
  • First pitch: 7:07 p.m. ET
  • Where: Rogers Centre (Toronto)
  • How to watch: Local TV

💡 Expert MLB predictions today


❓ Red Sox vs. Blue Jays FAQs

Who is favored to win Red Sox vs. Blue Jays ?

The Blue Jays are the -162 betting favorite to defeat the Red Sox at home on Tuesday.

What is the run line for Red Sox vs. Blue Jays?

Toronto is a -1.5 run line favorite (+135) against Boston in Tuesday’s matchup.

What is the Over/Under for Red Sox vs. Blue Jays?

The total for Tuesday’s game between the Red Sox and Blue Jays is 8, with the Over juiced to +100 and the Under -115. 

What are the best bets for Red Sox vs. Blue Jays?

My best bets for Tuesday’s Red Sox vs. Blue Jays game are Over 8 (+100) and Jarren Duran Over 1.5 hits, runs, and RBI (-106).

When is the Red Sox vs. Blue Jays game?

First pitch is set for 7:07 p.m. ET on Tuesday at Rogers Centre in Toronto.

How do baseball odds work?

When betting on MLB, the run line shows how many runs the favorite needs to win by in order to cash the bet. For example, a favorite of -1.5 must win by two or more runs to cover the run line, while an underdog at +1.5 must win outright or lose by one run to cover the run line.

Moneyline odds represent the payout for picking the outright winner (+200 means a $100 bet wins $200, while -200 means a $200 bet wins $100). Over/Unders let you wager on whether the combined total of runs will be higher or lower than the set number.

You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.

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