Mariners vs. Astros Prediction, Odds & Expert Picks: MLB Best Bets for Tonight Sept. 19
The Seattle Mariners (84-69) and Houston Astros (84-69) begin a crucial weekend series as I make my Mariners vs. Astros prediction for the opener at 8:10 p.m. ET on Friday at Daikin Park in Houston.
These two teams are tied at the top of the American League West division entering the final days of the regular season. The Astros have won the AL West in seven of the past eight years, while the Mariners are looking for their first division crown since 2001.
Houston is -110 to win Friday’s opener, which is a line worth taking as part of tonight’s MLB picks.
⚾ Mariners vs. Astros prediction
MLB odds subject to change.
- Moneyline pick: Astros (-110 via BetMGM) ⭐⭐⭐
- Run line pick: Astros +1.5 (-200 via FanDuel) ⭐⭐
- Over/Under pick: Under 7.5 (-119 via DraftKings) ⭐⭐
📝 Mariners vs. Astros preview & best bet
Track the latest MLB scores for line movement and matchup info.
🚀 Astros to win (-110) ⭐⭐⭐
I’ll believe the Astros will relinquish their AL West crown when they actually do it. This weekend could be a good opportunity for Houston to regain control of the division entering the final week of the regular season.
To be honest, this is more of a bet on Astros pitcher Hunter Brown in Friday’s series opener than anything else. Brown is 12-7 with a 2.27 ERA in 29 starts this season. He hasn’t allowed more than two earned runs in a start since July 20.
The Mariners are 9-1 over their last 10 games and have been much better offensively on the road than at home. But facing Brown is a different challenge, which is why I’ll side with Houston for Game 1 of this pivotal series.
💰 Best Mariners vs. Astros player prop bet
Our MLB player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
⬆️ Hunter Brown Over 17.5 outs (-130) ⭐⭐⭐⭐
The Astros couldn’t ask to be in a better position, handing the ball to their best pitcher on Friday night of a series that could decide the division. I expect them to trust Hunter Brown to get as many outs as possible, ensuring their bullpen is good to go for the rest of the weekend.
Brown has recorded at least 18 outs in six straight starts and seven of his past eight games since Aug. 1. This line is as high as -145 at BetMGM, meaning a -130 value ($7.69 profit on a $10 bet) is a reasonable discount.
📊 Mariners vs. Astros odds: Sept. 19
MLB odds update live in real time.
📈 Mariners vs. Astros betting odds analysis
The Astros began with -110 odds to win, but with 60% of wagers coming on their side, it wouldn’t be surprising to see this line move further in their direction. The total started at 7.5, though 62% of bets have come in on the Under.
🔢 Mariners vs. Astros stats
Season stats courtesy of baseball-reference.com.
| Mariners (84-69) | Statistic (per game) | Astros (84-69) |
|---|---|---|
| 4.73 | Runs | 4.26 |
| 8.3 | Hits | 8.5 |
| .244 | AVG | .252 |
| .419 | SLG | .400 |
| .739 | OPS | .717 |
| 3.91 | ERA | 3.83 |
| 8.7 | K/9 | 9.4 |
| 2.9 | BB/9 | 3.2 |
| 1.2 | HR/9 | 1.2 |
🚑 Mariners vs. Astros injury report
📺 Mariners vs. Astros game info
- When: Friday, Sept. 19
- Kickoff: 8:10 p.m. ET
- Where: Daikin Park (Houston)
- How to watch: Local TV
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❓ Mariners vs. Astros FAQs
Who is favored to win Mariners vs. Astros?
Friday’s series opener is priced as a coin flip, with both teams listed at -110 odds to win the game.
What is the run line for Mariners vs. Astros?
Seattle is a -1.5 run line favorite against Houston.
What is the Over/Under for Mariners vs. Astros?
The total for Friday’s Mariners-Astros matchup is 7.5.
What are the best bets for Mariners vs. Astros?
My best bets for Mariners vs. Astros are Houston moneyline and Hunter Brown Over 17.5 pitching outs.
When is the Mariners vs. Astros game?
First pitch for Mariners vs. Astros is 8:10 p.m. ET on Friday.
How do baseball odds work?
When betting on MLB, the run line shows how many runs the favorite needs to win by in order to cash the bet. For example, a favorite of -1.5 must win by two or more runs to cover the run line, while an underdog at +1.5 must win outright or lose by one run to cover the run line.
Moneyline odds represent the payout for picking the outright winner (+200 means a $100 bet wins $200, while -200 means a $200 bet wins $100). Over/Unders let you wager on whether the combined total of runs will be higher or lower than the set number.
You can determine the payouts and implied probabilities for any wager - or convert odds to different formats - with our odds converter.
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