Dodgers vs. Mariners Prediction: MLB Odds & Expert Picks for Sept. 26

My Dodgers vs. Mariners prediction expects a strong performance from the home team, led by Josh Naylor.
Dodgers vs. Mariners Prediction: MLB Odds, Expert Picks, Best Bets for Sept. 26
Pictured: Seattle Mariners third baseman Eugenio Suarez (28) raises the trident to celebrate a victory. Photo by Joe Nicholson-Imagn Images

The Seattle Mariners have been one of the hottest teams in baseball, something I’m expecting to continue as I put together my Dodgers vs. Mariners prediction. First pitch is set for 9:40 p.m. ET (Local TV) on Friday evening from T-Mobile Park in Seattle.

For my MLB picks, I think Mariners slugger Josh Naylor is in a great spot to continue his recent offensive hot streak, and I’m targeting the Over on one of his player props.


📊 Dodgers vs. Mariners odds

Latest MLB odds updated live in real time.

📺️ How to watch Dodgers vs. Mariners

When: Friday, Sept. 26

First pitch: 9:40 p.m. ET

Where: T-Mobile Park (Seattle)

TV: Local TV


⚾ Dodgers vs. Mariners predictions

MLB expert picks for Friday; odds subject to change.

  • Game pick: Mariners (-130 via bet365) ⭐⭐⭐
  • Over/Under pick: Over 7 (-115 via DraftKings) ⭐⭐⭐
  • Player prop bet: Josh Naylor Over 1.5 hits, runs, and RBI (+125 via DraftKings) ⭐⭐⭐

✅ Dodgers vs. Mariners expert pick

Track the latest MLB scores for line movement and matchup info.

🔱  Mariners -1.5  (+170) ⭐⭐⭐

Dodgers vs. Mariners Prediction: MLB Odds, Expert Picks, Best Bets for Sept. 26
Pictured: Seattle Mariners shortstop J.P. Crawford (3) celebrates after winning the AL West. Photo by Stephen Brashear-Imagn Images

The Mariners are the league’s hottest team and enter Friday’s matchup on a seven-game winning streak. Seattle has been excellent at home this season with an impressive 51-27 record at T-Mobile Park.

The Mariners are still very much in the hunt for the top seed in the American League, which would secure home-field advantage on the road to the World Series. The Dodgers, meanwhile, locked up the NL West on Thursday and don’t have much to play for over the season’s final weekend. I think this is a great spot to back a Seattle team on a major roll.

BetMGM is offering +170 odds on Seattle -1.5, which nets out a profit of $17.00 on a $10 bet. The +170 odds have an implied probability of 37.04%.

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💰 Dodgers vs. Mariners player prop bet

Our MLB player prop odds tool shows the best odds for every market across legal sportsbooks in your area.

⬆️ Josh Naylor Over 1.5 hits, runs, and RBI (+125) ⭐⭐⭐

Dodgers vs. Mariners Prediction: MLB Odds, Expert Picks, Best Bets for Sept. 26
Pictured: Seattle Mariners first baseman Josh Naylor (12) hits a home run. Photo by Erik Williams-Imagn Images

Mariners first baseman Josh Naylor has been swinging a hot bat of late, hitting .393 with two home runs, 13 RBIs, and 12 runs scored over his last 15 games. He also has an .845 OPS with 14 homers and 63 RBIs against right-handed pitching this season.

Dodgers pitcher Emmet Sheehan has been excellent in 2025, but is below average in barrel rate and hard-hit rate. Naylor sits in the 90th percentile in Baseball Savant’s squared-up metric. His ability to make solid contact with a 91st percentile strikeout rate should enable him to put together quality at-bats against Sheehan. 

A $10 bet on Naylor’s Over yields a profit of $12.50 at DraftKings. The +125 odds have an implied probability of 44.44%.

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