Best Home Run Predictions Today: MLB Odds, Picks & Prop Bets for Sept. 14

My best home run predictions for today include Corbin Carroll, Vinnie Pasquantino, and Mark Vientos, but feature Ian Happ (+540).

Mike Spector

Last Updated: September 14, 2025 7:08 AM EDT • 3 minute read

Home Run Predictions Today: Best MLB Odds, Picks & Prop Bets for Sept. 14 — Pictured: Corbin Carroll hits a three-run home run against the Boston Red Sox. Photo by Rick Scuteri via Imagn Images

Among the full 15-game MLB slate for Sunday are arguably the two best rivalries in the sport (Dodgers-Giants and Yankees-Red Sox), but I focus on the day’s interleague matchups with my best home run predictions today.

My MLB picks are centered around Chicago Cubs slugger Ian Happ, who has been one of the hottest hitters in the league over the last two weeks.

My best home run bets today also take fliers on Corbin Carroll, Vinnie Pasquantino, and Mark Vientos at potential juicy payouts. A $10 parlay on all four sluggers going yard would pay out over $5,100 in profits.

💰 MLB best home run predictions & odds today: Sept. 14

Best home run predictions today based on the latest MLB odds.

Vinnie Pasquantino to hit a home run (+475 via bet365) ⭐⭐⭐
Mark Vientos to hit a home run (+420 via FanDuel) ⭐⭐
Corbin Carroll to hit a home run (+251 via DraftKings) ⭐⭐⭐⭐
Ian Happ to hit a home run (+540 via FanDuel) ⭐⭐⭐

💣 Best home run prediction today: MLB expert picks & prop bets

Here is my favorite MLB home run bet today and analysis of why it leads my MLB home run predictions.

⚾ Ian Happ (Cubs) to hit a home run ⭐⭐⭐

Home Run Predictions Today: Best MLB Odds, Picks & Prop Bets — Pictured: Ian Happ rounds the bases after hitting a solo home run against the Washington Nationals. Photo by Kamil Krzaczynski-Imagn Images

Happ entered Saturday’s interleague matchup against the Tampa Bay Rays batting .373 with five home runs and 11 RBI over his previous 13 games. He homered in Friday’s series opener, his 21st of the season, which put him four shy of tying his single-season high set in both 2021 and 2024.

Happ now faces Rays righty Adrian Houser, against whom he has a .875 OPS in 16 career at-bats. Two of Happ’s four hits against Houser have gone for extra bases. And while none have been home runs, the righty has allowed at least one home run and three or more earned runs in three of his last four starts.

The highest implied probability for Happ to homer is 16.67% (a 1-in-6 chance) based on bet365’s +500 odds. But the best payout is at FanDuel, with its +540 odds profiting $54 on a winning $10 wager.

📊 Rays vs. Cubs odds

🚀 Best home run parlay picks

Use our parlay calculator to get the best odds for any parlay.

Vinnie Pasquantino to hit a home run (+370 via FanDuel)
Mark Vientos to hit a home run (+400 via FanDuel)
Corbin Carroll to hit a home run (+240 via FanDuel)
Ian Happ to hit a home run (+540 via FanDuel)

Parlay odds: +51036 via FanDuel ($10 to win $5,103.60)

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❓ Best home run predictions FAQs

What are the best home run props for tonight?

My best home run predictions today feature Corbin Carroll, Ian Happ, Vinnie Pasquantino, and Mark Vientos.

What is a home run bet?

A home run bet is a wager on a hitter to hit a HR at any point during a game. Some sportsbooks allow you to bet on a hitter to not hit a home run, but the most common bet is on them to do so.

Can you parlay home run bets?

Yes, you can parlay home run bets. We've provided our best home run parlay today.

How do I place a home run bet?

To place a home run bet, simply go to your favorite sportsbook and go to the game featuring the player of your choice. Then click on batter props and you should see an option to bet a player to hit a home run.

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Written by:
Mike Spector

Mike started in the sports writing industry in July 2019, and gained a lot of followers in his first year after finishing with the No. 2 overall record in an annual NFL betting competition, which made picks against the spread, and from an Over/Under and moneyline perspective. Mike is an avid fan of the NFL, MLB, tennis, and all college sports. In his opinion, March Madness is the best sporting event there is, and he's especially euphoric starting with conference tournament time in college basketball. Mike's a big advocate of "fading the public" and making plays that are contrarian, constantly citing that "there are reasons why they have those big shiny buildings in Las Vegas." When making wagers, Mike leans on his NFL experience and always scours the best odds at all of the major sports betting sites, where he mostly sifts through DraftKings, FanDuel, BetMGM, and bet365. He's tried several others and is of the firm belief that bettors should not just stick to one sportsbook, as there is always likely better value to be had with the same wager. In addition, while Mike received his undergraduate degree from Villanova University, he has no issue betting against the Wildcats when it comes to college basketball wagering, and suggests other bettors should always put their “head” before their “hearts.”