Best Home Run Predictions Today: MLB Odds, Picks & Prop Bets for June 16

We're turning to some of MLB's biggest names, like Shohei Ohtani and Mike Trout, to cash our home run picks on Monday.

Gabe Henderson

Last updated: June 16, 2025 10:05 AM EDT • 3 min read

Home Run Predictions Today: Best MLB Odds, Picks & Prop Bets for June 16 — Pictured: Los Angeles Angels designated hitter Mike Trout (27) hits a single against the Athletics. Photo by Gary A. Vasquez via Imagn Images.

After a rough start to the week, we're turning to some of the league's biggest stars to get us back on track with our best home run predictions today. We're relying on a pair of former teammates who now rule different sides of Los Angeles, with Mike Trout and Shohei Ohtani on our dinger cards this evening.

A $10 winning wager on today's home run parlay would profit nearly $5,000!

💰 MLB best home run predictions & odds today: June 16

Here are my best MLB home run predictions and odds today with my pick confidence based on a 1-to-5-star scale. You can also check out our MLB player prop odds tool for the latest MLB odds at the best legal sportsbooks in your region.

🧨 Mike Trout player prop pick: To hit a home run (+340 via BetMGM) ⭐⭐⭐
🧨 Shohei Ohtani player prop pick: To hit a home run (+215 via FanDuel) ⭐⭐⭐
🧨 Jose Altuve player prop pick: To hit a home run (+525 via bet365) ⭐⭐⭐
🧨 Jorge Polanco player prop pick: To hit a home run (+520 via FanDuel) ⭐⭐

🚀 Best home run parlay picks

Here is our best MLB home run parlay for Monday's baseball action; use our parlay calculator to get the best odds for any parlay.

💣 Mike Trout to hit a home run (+340 via FanDuel)
💣 Shohei Ohtani to hit a home run (+215 via FanDuel)
💣 Jose Altuve to hit a home run (+480 via FanDuel)
💣 Jorge Polanco to hit a home run (+520 via FanDuel)

Parlay odds: +49741 via FanDuel ($10 to win $4,974.06)

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💣 Best home run prediction today: MLB expert picks & prop bets

Here's my best home run prop prediction today. Check out the rest of our MLB picks along with our guide on how to bet on MLB.

⚾ Mike Trout (Angels) to hit a home run ⭐⭐⭐

Best odds: +340 via BetMGM (bet $10 to win $34)

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Trout is starting to look healthy again, as the three-time American League MVP is hitting .308 over his last 15 games. Los Angeles's offense has flatlined with just 15 runs across the last five games. But we expect Prince Fish to take matters into his own hands tonight in the Bronx and lead the Angels Over Ballpark Pal's 3.75 expected runs total.

Trout has a career .333 batting average at Yankee Stadium, crushing seven round-trippers in 26 games played in the iconic venue. He's also found relative success (.667, 1 XBH), albeit with a small sample size, against Yankees starter Clarke Schmidt. We'll cast a wide net tonight in hopes of catching a Trout at +340 with our best sports betting apps.

📊 Angels vs. Yankees odds

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💵 Best MLB betting sites

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Written By:
Gabe Henderson

Gabe Henderson is a sports betting writer from Houston, Texas. He graduated from Louisiana State University in 2022 with a bachelor's degree in Mass Communication. Gabe developed an interest in sports betting while in college due to its legalization in Louisiana. He turned his passion into a career shortly after, joining The Advocate/NOLA.com as a Sports Betting Content Coordinator, where he spent two years. Gabe wore many hats before graduating as he led FanSided's coverage of Chelsea FC as a Site Expert with "The Pride of London." He was also the Editor-in-Chief of the LSU Gumbo Yearbook for two years. Gabe became a part of the SportsbookReview.com team in late 2024. He brings with him an extensive knowledge of many sports, including — but not limited to — NFL, NCAA, MLB, NBA, soccer, and UFC.