Best Home Run Predictions Today: MLB Odds, Picks & Prop Bets for Aug. 18

Last Updated: August 18, 2025 8:08 AM EDT • 3 minute read X Social Google News Link

Detroit slugger Riley Greene is hitting 1.000 against Houston's starter ahead of tonight's showdown between American League division leaders, which is why he leads the best home run predictions today.
Greene has already surpassed his previous career high in home runs for a single campaign, and he can inch closer to the 30-home run mark this evening. My home run bets today also look to Shohei Ohtani, Salvador Perez, and Eugenio Suarez to climb the dinger charts with their contributions.
If all four players leave the park tonight, a $10 parlay at the best MLB betting sites would pay out nearly $2,200!
💰 MLB best home run predictions & odds today: Aug. 18
Here are my best MLB home run predictions and odds today with my pick confidence based on a 1-to-5-star scale. You can also check out our MLB player prop odds tool for the latest MLB odds at the best legal sportsbooks in your region.
🧨 Riley Greene to hit a home run (+500 via bet365) ⭐⭐⭐⭐
🧨 Eugenio Suarez to hit a home run (+390 via bet365) ⭐⭐⭐
🧨 Salvador Perez to hit a home run (+390 via bet365) ⭐⭐⭐
🧨 Shohei Ohtani to hit a home run (+164 via FanDuel) ⭐⭐⭐⭐
🚀 Best home run parlay picks
Here is our best MLB home run parlay for Monday's baseball action; use our parlay calculator to get the best odds for any parlay.
💣 Riley Greene to hit a home run (+390 via FanDuel)
💣 Eugenio Suarez to hit a home run (+285 via FanDuel)
💣 Salvador Perez to hit a home run (+340 via FanDuel)
💣 Shohei Ohtani to hit a home run (+164 via FanDuel)
Parlay odds: +21813 via FanDuel ($10 to win $2,181.36)
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💣 Best home run prediction today: MLB expert picks & prop bets
Here are my best home run bets today. Check out the rest of our MLB picks along with our guide on how to bet on MLB.
⚾ Riley Greene (Tigers) to hit a home run ⭐⭐⭐⭐
Best odds: +500 via bet365 (bet $10 to win $50)
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Greene has been one of Detroit's biggest keys to success this season. He leads the American League Central in hits, home runs, RBIs, and a number of key categories, in addition to playing at a Gold Glove level in left field. He's clubbed 28 homers this season and looks poised to add to that tally at home tonight.
While Greene hasn't been as proficient a power hitter at Comerica Park, Houston's starter has struggled mightily away from Daikin Park. Spencer Arrighetti hasn't made it out of the fourth frame in either one of his road starts this season, going 3 2/3 innings in each with five earned runs.
The outfielder has only cashed this prop at a 20% clip over his previous 10 outings. However, he's batting 1.000 against Arrighetti all-time, and both of those hits have been homers. I'm banking on Greene to take advantage of the Astros' struggling starter tonight. If he does and clubs home run No. 29, a $10 wager will return $50 in profits at the best sports betting sites.
📊 Astros vs. Tigers odds
💡 Expert MLB predictions today
- MLB home run predictions today
- Best NRFI bets today
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