⚾ MLB Best Bets for Opening Day: Predictions & Prop Picks for March 26

My MLB player props break down the best prop bets I'm playing across Opening Day, featuring Kyle Tucker and Paul Skenes.
Pittsburgh Pirates starting pitcher Paul Skenes - who's featured in my MLB best bets for Opening Day - high-fives in the dugout.
Pictured: Pittsburgh Pirates starting pitcher Paul Skenes - who's featured in my MLB best bets for Opening Day - high-fives in the dugout. Photo by: Charles LeClaire-Imagn Images
Enjoying SBR content? Add us as a preferred source on your Google account Add as a preferred source on Google

📡 SBR Edge: Best bets for Opening Day

The sweet smell of baseball is back in the air, and I've got my best bets for Opening Day to get you ready for first pitch. From Paul Skenes to Kyle Tucker, we've got plenty of star power to build that bankroll on the first day of the season. You'll find bonus game picks along the way, too - let's dive in and take advantage of the books.


⚾ MLB best bets for Opening Day: March 26

See all of our experts’ MLB picks based on the latest MLB odds.

⚾ Best bets (FanDuel) πŸ’΅ Units πŸ“ Notes
Paul Skenes Over 6.5 strikeouts (+104) 1u β†’ 1.04u 26% K rate vs. Mets
Tarik Skubal Over 18.5 outs (-125) 1u β†’ 0.80u Padres hitting just .157 AVG vs. Skubal
Kyle Tucker 2+ total bases (-110) 1u β†’ 0.90u 6-for-18 (2 2B) vs. Zac Gallen 
Julio Rodriguez 2+ total bases (+120) 1u β†’ 1.20u .417 xBA vs. Tanner Bibee

Total wagered: 4 units | Max profit: 3.90 units

📃 Affiliate disclosure

Sportsbook Review may receive a commission if you sign up through our links. Not intended for use in MA. Bonuses not applicable in Ontario. 21+ only. (Gambling problem? Call 1-800-GAMBLER)


πŸ’° Best bets for Opening Day 

Kyle Tucker 2+ total bases vs. Diamondbacks (-110)

New team, same Tucker, at least that's what we're looking for against a pitcher he's historically dominated. One of the most protected hitters in baseball in that Dodgers' lineup owns a .370 xwOBA against Gallen and has delivered three extra-base hits against the DBacks' ace across just 18 plate appearances. It helps that Tucker owns better splits against right-handers, too. With an average exit velocity close to 94 MPH off Gallen, look for Tucker to square a couple up on Opening Day, and for this to cash early into the ballgame.

📡 SBR Edge: Take Dodgers -1.5 (-118)

Los Angeles as a team owns a .340 wOBA against Gallen and is hitting for a .274 AVG. Not bad when you consider this Diamondbacks team can't touch Yoshinobu Yamamoto. The Dodgers ace strikes out Arizona at a 30% rate, while the lineup hits just .161 and owns a .236 xwOBA. Look for Los Angeles to handle business on Opening Day.


πŸ”₯ More MLB player prop picks for Opening Day

Julio Rodriguez 2+ total bases vs. Guardians (+120)

This type of value on J-Rod is absurd, and it's one of my best bets on the board for Opening Day as a result. Not only does Rodriguez carry a .417 xBA to the plate against Tanner Bibee, but I'm expecting to see some positive regression early in the season after recording his lowest barrel percentage of his career in 2025. Rodriguez puts the ball in play and sees it well against Bibee specifically, which should help us cash our first plus-money play of the year.

Paul Skenes Over 6.5 strikeouts vs. Mets (+104)

We all know Skenes is one of the best strikeout pitchers in baseball. He owned a top-10 whiff percentage and top-10 K rate among qualified starters a season ago, and is ramped up after pitching in the World Baseball Classic. The Mets have struck out at a 25% rate against him across 31 plate appearances, too - let's watch him carve on Opening Day.


πŸš€ Best MLB parlay picks today

We're rocking with three plays that all own their specific matchups for Opening Day. Tucker loves himself some Gallen, Rodriguez puts the ball in play vs. Bibee, and Skenes has a history of dicing up the Mets. Let's throw them all in a parlay together and see what's on the other side, shall we?

💵 Best MLB parlay bet today

  • Kyle Tucker 2+ bases (-110)
  • Julio Rodriguez 2+ bases (+120)
  • Paul Skenes 7+ strikeouts (+104)

Best odds: +757 via FanDuel (.2u -> 1.51u)


πŸ’΅ My betting record for MLB picks

All MLB picks, including SGPs, have been tracked since March 25.

Bet type Record Net profit ROI
Overall 0-0-0 +0.00 units βœ… X.X% βœ…
Player props 0-0-0 +0.00 units βœ… X.X% βœ…
Parlays 0-0-0 +0.00 units βœ… X.X% βœ…

πŸ’‘ How I'm betting MLB player props for Opening Day

Follow all of our MLB analysis and expert predictions for baseball season.

There's a reason why I went quite heavy (four units will not be placed every day of the year) - it's Opening Day for all those who celebrate, and I absolutely love the mismatches I've found. For plus-money wagers, I usually expose .5u of my bankroll and will keep that in mind throughout the lengthy 162-game season. Remember to think of bankroll management throughout the year if you're going to be a profitable bettor.