College Football National Championship Odds: Biggest Week 5 Takeaways and Betting Movement

After Week 5, Ohio State (+525) is the college football national championship odds favorite, followed by Oregon (+600), Penn State (+800), and Texas (+800).
College Football National Championship Odds: Biggest Week 5 Takeaways and Betting Movement
Pictured: Ohio State wide receiver Jeremiah Smith (4) scores a touchdown against Washington. Photo by Joe Nicholson via Imagn Images.

There was no shortage of powerhouse matchups on the college football slate in Week 5 ... and as a result, the Big Ten's grip on the college football national championship odds only tightened after an electric Saturday night.

The reigning national champions, Ohio State, remain the favorites to repeat after beating Washington, 24-6, on the road in Week 5. However, there's a new team directly behind the Buckeyes on the oddsboard, after Oregon took down Penn State, 30-24, on the road in double overtime.

The Buckeyes, Ducks, and Nittany Lions remain the three biggest favorites - the only change was Oregon jumping Penn State - and your college football picks should focus on backing the Big Ten to win its third straight national championship. 


🔀 Week 5 national championship odds movement & key takeaways

  • Following a second-half surge to take down Washington, Ohio State saw its national championship odds shortened from +575 to +525, as the Buckeyes remain the consensus favorites
  • With its double overtime win on the road, Oregon is now the second biggest favorite behind Ohio State, with the Ducks' odds moving from +700 to +600 - Penn State saw its odds lengthen from +700 to +800
  • Alabama has completely reinvigorated its odds by taking down Georgia, with the Crimson Tide moving from +1400 to +850 while the Bulldogs lengthened from +750 to +1000
  • Both Texas (+800) and Miami (+1600) were on a bye during Week 5 and saw minimal change in their odds
  • One non-traditional power that jumped up the board was Ole Miss, moving from +2800 to +2000 after beating an LSU team that has seen its odds lengthen from +1000 to +2700 over the last few weeks
  • Though the return of Florida State as a potential challenger didn't last long, the Seminoles' odds were in the +2500 range, but following their overtime loss to Virginia, they're now +10000

📊 Live college football national championship odds 2025-26

The latest college football national championship odds; see all of the latest college football odds in real time.


❓ College football national championship FAQs

Who is the college football national championship odds favorite?

Ohio State (+525) is the college football national championship odds favorite. The Buckeyes' odds imply a 16% probability that they'll win the title for the second straight season.

When will the college football national championship be decided?

The 2026 college football national championship will be decided on Monday, Jan. 19.

When does the College Football Playoff start?

The 2025-2026 College Football Playoff begins Friday, Dec. 19, with the first of four first-round games; the other three will be played Saturday, Dec. 20. The quarterfinal games will then be played on Wednesday, Dec. 31, and Thursday, Jan. 1.

The semifinal games will be Thursday, Jan. 8, and Friday, Jan. 9, with the championship game slated for Monday, Jan. 19, at Hard Rock Stadium in Miami Gardens, Fla.

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