Villarreal vs. Manchester City Prediction: Champions League Odds, Expert Picks & Best Bets

Last Updated: October 20, 2025 4:42 PM EDT • 2 minute read X Social Google News Link

My Villarreal vs. Manchester City prediction picks the visitors to emerge victorious at the Estadi de la Ceramica in Spain, where the action starts at 3 p.m. ET on Paramount.
As part of our Champions League predictions, I’m picking the -138 betting favorite, Manchester City, to win a game that should feature lots of goals at both ends of the pitch. I also include one Manchester City playmaker to target as player prop pick who I expect to have a strong performance against the Spanish hosts.
⚽ Villarreal vs. Manchester City predictions
Soccer picks for Tuesday; odds subject to change.
- Game pick: Manchester City ML (-138 via bet365) ⭐⭐⭐⭐
- Over/Under pick: Over 2.5 (-160 via Caesars) ⭐⭐⭐⭐
- Player prop pick: Tijjani Reijnders assist (+390 via DraftKings) ⭐⭐⭐
✅ Villarreal vs. Manchester City best bet
⬆️ Over 2.5 total goals (-160) ⭐⭐⭐⭐
With both teams sporting impressive attacking records heading into Tuesday’s contest, I’m backing the total to go Over 2.5 goals.
Villarreal have 10 goals in their last six games, so expect them to create opportunities to score at home, where they last held Juventus to a 2-2 draw in the Champions League. However, it’s also going to be a busy day for Villarreal’s defense again.
Manchester City will see plenty of the ball, which should lead to opportunities for one of Europe’s most potent attacks to terrorize Villarreal’s shaky defense. Manchester City, winners of six of their last eight games, are averaging over two goals a game and have 23 goals in all competitions this season.
A $10 bet at Caesars on both teams scoring will net a profit of $6.20
💰 Best Villarreal vs. Manchester City player prop bet
Our player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
🔥 Tijjani Reijnders assist (+390) ⭐⭐⭐
With Erling Haaland playing some of the best soccer of his career, it might be wise to bet on a Manchester City playmaker getting an assist. Tijjani Reijnders could be a decent bet to register a helper for the Norwegian forward, or any of City’s other potent forwards.
The Dutch midfielder, who arrived at City from AC Milan last summer, has three assists in all competitions, with two of those assists helping Haaland score.
Jeremy Doku is another good candidate to get an assist, but I’m backing Reijnders' vision and passing skills to aid in Manchester City’s scoring efforts against what should be a difficult Villarreal team. A $10 bet on Reijnders getting an assist at DraftKings will net a profit of $39.
📊 Villarreal vs. Manchester City odds
Champions League odds updated live in real time.
📺 How to watch Villarreal vs. Manchester City
- Date: Tuesday, Oct. 21
- Kickoff: 3 p.m. ET
- Where: Estadi de la Ceramica
- TV: Paramount+
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Gordon Brunt